- Expression of growth factor, extracellular matrix and antioxidant (N-acetylcysteine) effect in TGF beta1 treated rat lens system
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Park MS, Ahn CS, Hong YS
- KMID: 2206311
- J Korean Ophthalmol Soc.
- 2002 Dec;43(12):2543-2554.
PURPOSE: The objective of this study was to characterize transdifferentiated lens epithelial cells analyzed by reverse transcription-polymerase chain reaction (RT-PCR) for the expression of mRNAs encoding growth factors, growth factor... -
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- Increased expression of the epidermal growth factor receptor gene in psoriasis
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Choi YY, Lee KS, Lee SS, Chang ES, Song JY
- KMID: 2303592
- Korean J Dermatol.
- 1992 Aug;30(4):431-438.
Psoriasis is characterized by disregulation of keratinocyte growth with profound epidermal hyperplasia. Keratinocyte hyperplasia in psoriasis may be expained in part by overproduction of growth factor, and by altered metabolism... -
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- Expression of the mRNA of Growth Factor Receptors and Neurotrophic Factors in Porcine Vesical Submucosa and Acellular Matrix
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Moon HC, Joo KJ, Park HJ
- KMID: 2293814
- Korean J Urol.
- 2005 Dec;46(12):1344-1347.
PURPOSE: Several naturally-derived biopolymers have been introduced as implantable biomaterial for tissue reconstruction, and some of them are already being applied in various clinical fields. They serve as backbones for... -
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- Association Study of Fibroblast Growth Factor 2 and Fibroblast Growth Factor Receptors Gene Polymorphism in Korean Ossification of the Posterior Longitudinal Ligament Patients
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Jun JK, Kim SM
- KMID: 2190516
- J Korean Neurosurg Soc.
- 2012 Jul;52(1):7-13.
- doi: 10.3340/jkns.2012.52.1.7
OBJECTIVE: The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) of fibroblast growth factor (FGF) 2 gene and fibroblast growth factor receptor (FGFR) genes are associated... -
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- Study on Immunohistochemical Expression of p53, Epidermal Growth Factor and c-erbB-2 in Squamous Cell Carcinoma of the Head and Neck
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Lee DY, Im DM, Do NY, Na HJ, Choi JS, Kim SH, Kee KH
- KMID: 2074245
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Apr;44(4):412-417.
BACKGROUND AND OBJECTIVES: Cell proliferation and differentiation are regulated by growth factors and growth factor receptors. Inappropriate expressions of growth factors and oncogenes may influence the biological and clinical phenotype... -
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- Identification of UVB Effects on Gene Expressed by Normal Human Melanocytes
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Kim HS, Park HH, Lee MH
- KMID: 1977852
- Korean J Dermatol.
- 2003 Dec;41(12):1597-1602.
BACKGROUND: Irradiation of the skin with ultraviolet rays result in alterations of immune response as well as melanogenesis and melanocarcinogenensis. These effects are largely mediated by soluble mediators released from... -
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- A Study on the Expression of Transforming Growth Factor-alpha, Epidermal GrowthFactor and Epidermal Growth Factor Receptor in Thyroid Tumors
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Lee DY, Doh NY, Na HJ, Kim YG, Im TS, Choi YH, Lee MJ
- KMID: 2274481
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Sep;41(9):1174-1179.
BACKGROUND AND OBJECTIVES: Cell proliferation and differentiation are regulated by growth factors and growth factor receptors. Inappropriate expressions of growth factors and altered responsiveness of growth factor receptors may influence... -
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- Expression of the EGF Receptor Gene Family in Gastric Cancer
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Lee HW, Choi EY, Bae CD, Ryu BY, Yu HJ, Yang HK, Kim JP
- KMID: 2206406
- J Korean Surg Soc.
- 1998 Oct;55(4):498-513.
Growth factor receptors play critical roles in the regulation of normal growth and developement. Some of these molecules have been implicated in the neoplastic process as well. In this study,... -
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- The Study of CYFRA 21-1 and Epidermal Growth Factor Receptor Levels in Cancer Tissue of Bronchogenic Carcinoma Patients
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Kim DY, Kim SM
- KMID: 2061922
- Korean J Thorac Cardiovasc Surg.
- 1997 Sep;30(9):854-861.
CYFRA 21-1 is known to be a cytokeratin 19 fragment, and it can be detected by using two specific monoclonal antibodies (KS 19-1 and BM 19-21) and can be clinically... -
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- Heterogeneity of Human γδ T Cells and Their Role in Cancer Immunity
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Lee HW, Chung YS, Kim TJ
- KMID: 2471045
- Immune Netw.
- 2020 Feb;20(1):e5.
- doi: 10.4110/in.2020.20.e5
The γδ T cells are unconventional lymphocytes that function in both innate and adaptive immune responses against various intracellular and infectious stresses. The γδ T cells can be exploited as... -
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- Effect of EGF and TGF- on Cellular Adhesion and the Expression of E-cadherin and EGF Receptor in Cervical Cancer Cell Lines
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Shin JH, Moon HS, Park HY, Kim JI, Yoo HK
- KMID: 2261406
- Korean J Obstet Gynecol.
- 1999 Jun;42(6):1286-1293.
OBJECTIVE: Invasive squamous cell carcinoma is known to have undifferentiated epithelial cell, decreased cell adhesion and increased invasiveness of tumor cell and decreased expression of cell adhesive factors known as... -
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- In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors
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Baek SJ, Kang SK, Ra JC
- KMID: 1123372
- Exp Mol Med.
- 2011 Oct;43(10):596-603.
- doi: 10.3858/emm.2011.43.10.069
The homing properties of adipose tissue-derived mesenchymal stem cells (AdMSCs) have stimulated intravenous applications for their use in stem cell therapy. However, the soluble factors and corresponding cellular receptors responsible... -
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- Optimized Image-Based Surrogate Endpoints in Targeted Therapies for Glioblastoma: A Systematic Review and Meta-Analysis of Phase III Randomized Controlled Trials
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Suh CH, Kim HS, Jung SC, Choi CG, Kim SJ, Kim KW
- KMID: 2471813
- Korean J Radiol.
- 2020 Apr;21(4):471-482.
- doi: 10.3348/kjr.2019.0839
OBJECTIVE: We aimed to determine the optimized image-based surrogate endpoints (IBSEs) in targeted therapies for glioblastoma through a systematic review and meta-analysis of phase III randomized controlled trials (RCTs). MATERIALS AND... -
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- Inhibition of eNOS/sGC/PKG Pathway Decreases Akt Phosphorylation Induced by Kainic Acid in Mouse Hippocampus
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Lee SH, Byun JS, Kong PJ, Lee HJ, Kim DK, Kim HS, Sohn JH, Lee JJ, Lim SY, Chun W, Kim SS
- KMID: 1457699
- Korean J Physiol Pharmacol.
- 2010 Feb;14(1):37-43.
- doi: 10.4196/kjpp.2010.14.1.37
The serine/threonine kinase Akt has been shown to play a role of multiple cellular signaling pathways and act as a transducer of many functions initiated by growth factor receptors that... -
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- Epigallocatechin-3-gallate inhibits paracrine and autocrine hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion
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Kwak IH, Shin YH, Kim M, Cha HY, Nam HJ, Lee BS, Chaudhary , Pai KS, Lee JH
- KMID: 1097268
- Exp Mol Med.
- 2011 Feb;43(2):111-120.
- doi: 10.3858/emm.2011.43.2.013
Aberrant activation of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor, Met, is involved in the development and progression of many human cancers. In the cell-based screening assay, (-)epigallocatechin-3-gallate (EGCG)... -
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- Hepatocyte Growth Factor/c-Met Signaling in Regulating Urokinase Plasminogen Activator in Human Stomach Cancer: A Potential Therapeutic Target for Human Stomach Cancer
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Lee KH, Choi EY, Hyun MS, Jang BI, Kim TN, Kim SW, Song SK, Kim JH, Kim JR
- KMID: 1782247
- Korean J Intern Med.
- 2006 Mar;21(1):20-27.
- doi: 10.3904/kjim.2006.21.1.20
BACKGROUND: Up-regulation of the hepatocyte growth factor (HGF), its transmembrane tyrosine kinase receptor (c-Met), and urokinase type plasminogen activator (uPA), is associated with the development and metastasis of various... -
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- Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
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Park HY, Kwon HM, Lim HJ, Hong BK, Lee JY, Park BE, Jang YS, Cho SY, Kim HS
- KMID: 1085746
- Exp Mol Med.
- 2001 Jun;33(2):95-102.
Leptin, the product of ob gene, is an endocrine hormone that regulates adipose tissue mass. Recently, leptin has been found to generate a growth signal involving a tyrosine kinase-dependent intracellular... -
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- Heat shock proteins and their role in early mammalian development
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Walsh DA, Edwards MJ MJ, Smith MS
- KMID: 2052789
- Exp Mol Med.
- 1997 Sep;29(3):139-150.
Elevated body temperature can result from many agents in the natural environment, such as fever, hot weather and heavy exercise. In our modern living conditions additional sources of induced hyperthermia... -
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- MET Expression in Sporadic Renal Cell Carcinomas
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Choi JS, Kim MK, Seo JW, Choi YL, Kim DH, Chun YK, Ko YH
- KMID: 2157819
- J Korean Med Sci.
- 2006 Aug;21(4):672-677.
- doi: 10.3346/jkms.2006.21.4.672
Although germline mutations of met proto-oncogene on human chromosome 7q31-34 have been known as useful molecular markers of hereditary papillary renal cell carcinoma (RCC), the expression of MET, a product... -
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