- Calcium Sensing Receptor
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Kim SW, Shin CS
- KMID: 2200303
- J Korean Soc Endocrinol.
- 2003 Jun;18(3):250-260.
No abstract available. -
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- De novo a novel variant of CaSR gene in a neonate with congenital hypoparathyroidism
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Moon JE, Lee SJ, Park SH, Kim J, Jin DK, Ko CW
- KMID: 2417769
- Ann Pediatr Endocrinol Metab.
- 2018 Jun;23(2):107-111.
- doi: 10.6065/apem.2018.23.2.107
Autosomal-dominant hypocalcemia with hypercalciuria (ADHH) is a genetic disease characterized by hypoparathyroidism with hypercalciuria. Most patients with ADHH have calcium-sensing receptor (CaSR) gene mutations. The CaSR gene controls parathyroid secretions,... -
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- Autosomal Dominant Hypocalcemia Caused by an Activating Mutation of the Calcium-Sensing Receptor Gene: The First Case Report in Korea
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Kim MY, Tan AH, Ki CS, Lee JI, Jang HW, Shin HW, Kim SW, Min YK, Lee MS, Lee MK, Kim KW, Chung JH
- KMID: 1779268
- J Korean Med Sci.
- 2010 Feb;25(2):317-320.
- doi: 10.3346/jkms.2010.25.2.317
Hypoparathyroidism is an abnormality of calcium metabolism characterized by low serum levels of parathyroid hormone in spite of hypocalcemia. The causes of hypoparathyroidism are numerous. Activating mutations in the calcium-sensing... -
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- Autosomal dominant hypocalcemia with Bartter syndrome due to a novel activating mutation of calcium sensing receptor, Y829C
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Choi KH, Shin CH, Yang SW, Cheong HI
- KMID: 1802615
- Korean J Pediatr.
- 2015 Apr;58(4):148-153.
- doi: 10.3345/kjp.2015.58.4.148
The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium... -
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- Calcium and Cardiovascular Disease
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Reid IR, Birstow SM, Bolland MJ
- KMID: 2389814
- Endocrinol Metab.
- 2017 Sep;32(3):339-349.
- doi: 10.3803/EnM.2017.32.3.339
Circulating calcium is a risk factor for vascular disease, a conclusion arising from prospective studies involving hundreds of thousands of participants and extending over periods of up to 30 years.... -
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- Functional Analysis and Immunochemical Analyses of Ca²⺠Homeostasis-Related Proteins Expression of Glaucoma-Induced Retinal Degeneration in Rats
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Lee JY, Oh SJ
- KMID: 2405305
- Exp Neurobiol.
- 2018 Feb;27(1):16-27.
- doi: 10.5607/en.2018.27.1.16
The retinal degeneration resulting from elevated intraocular pressure was evaluated through functional and morphological analyses, for better understanding of the pathophysiology of glaucoma. Ocular hypertension was induced via unilateral episcleral... -
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- A Case of Familial Hypocalciuric Hypercalcemia Coexisting with Low Bone Mass
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Chun SW, Kim SH, Jung JY, Suh WN, Moon JA, Yook JI, Chung YS, Rhee Y, Lee EJ, Lim SK
- KMID: 2391917
- J Korean Endocr Soc.
- 2006 Dec;21(6):583-588.
Familial hypocalciuric hypercalcemia is caused by heterozygous loss-of-function mutation of the calcium sensing receptor gene, and this is characterized by mild, persistently elevated levels of serum calcium without symptoms or... -
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- A Case of Familial Hypocalciuric Hypercalcemia Coexisting with Hypothyroidism
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Kim EJ, Park SY, Kang JG, Kim CS, Ihm SH, Yoo HJ, Lee SJ
- KMID: 2259298
- Korean J Med.
- 2011 Jun;80(6):718-722.
Familial hypocalciuric hypercalcemia (FHH) is a genetic disorder characterized by mild asymptomatic hypercalcemia, hypocalciuria, a decreased urinary calcium-creatinine ratio, and normal or elevated parathyroid hormone levels. FHH is caused by... -
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- The extracellular calcium sensing receptor is expressed in mouse mesangial cells and modulates cell proliferation
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Kwak JO, Kwak J, Kim HW, Oh KJ, Kim YT, Jung SM, Cha SH
- KMID: 1089455
- Exp Mol Med.
- 2005 Oct;37(5):457-465.
The extracellular calcium sensing receptor (CaSR) belongs to the type III family of G-protein-coupled receptors, a family that comprises the metabotropic glutamate receptor and the putative vomeronasal organ receptors. The... -
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- Calcium-sensing receptor-mediated L-tryptophan-induced secretion of cholecystokinin and glucose-dependent insulinotropic peptide in swine duodenum
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Zhao X, Xian Y, Wang C, Ding L, Meng X, Zhu W, Hang S
- KMID: 2407617
- J Vet Sci.
- 2018 Mar;19(2):179-187.
- doi: 10.4142/jvs.2018.19.2.179
This study aimed to elucidate the effect of tryptophan (Trp) on gut hormone secretion as well as the roles of the calcium-sensing receptor (CaSR) and its downstream signaling pathway in... -
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- A Case Report of Familial Benign Hypocalciuric Hypercalcemia: A Mutation in the Calcium-Sensing Receptor Gene
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Woo SI, Song H, Song KE, Kim DJ, Lee KW, Kim SJ, Chung YS
- KMID: 1110751
- Yonsei Med J.
- 2006 Apr;47(2):255-258.
- doi: 10.3349/ymj.2006.47.2.255
Familial benign hypocalciuric hypercalcemia (FBHH) is an autosomal dominant trait with high penetrance, clinically manifestating a relatively benign, lifelong, persistent hypercalcemia and hypocalciuria without hypercalcemic related complications. The calcium-sensing receptor... -
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- Kidney and Calcium Homeostasis
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Jeon US
- KMID: 2134808
- Electrolyte Blood Press.
- 2008 Dec;6(2):68-76.
- doi: 10.5049/EBP.2008.6.2.68
Plasma calcium concentration is maintained within a narrow range (8.5-10.5 mg/dL) by the coordinated action of parathyroid hormone (PTH), 1,25(OH)2D3, calcitonin, and ionized calcium (iCa2+) itself. The kidney plays a... -
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- Interleukin-1beta, Calcium-Sensing Receptor, and Urokinase Gene Polymorphisms in Korean Patients with Urolithiasis
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Kim JY, Kim YS, Jang IH, Jung JD, Kim TH, Kim HR
- KMID: 2315522
- Korean J Urol.
- 2011 May;52(5):340-344.
PURPOSE: There are various causes of ureter calculi, and genetic factors are known to play a role. Interleukin-1beta (IL-1beta) and calcium-sensing receptor (CaSR) genes are related to hypercalciuria, and urokinase... -
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- Calcemic response to burns differs between adults and children: A review of the literature
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Klein GL, Benjamin D, Herndon DN
- KMID: 2404900
- Osteoporos Sarcopenia.
- 2017 Dec;3(4):170-173.
- doi: 10.1016/j.afos.2017.10.001
OBJECTIVES: The calcemic and parathyroid hormone (PTH) responses to severe burn injury appear to differ between children and adults. In our limited studies children exhibited hypocalcemic hypoparathyroidism consistent with up-regulation... -
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- Calcium-Sensing Receptor Gene Polymorphism is Associated with the Parathyroid Response to Low Calcium Dialysate in Hemodialysis Patients with Low Parathyroid Hormone Secretion
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Park TJ, Seo JW, Pack KM, Chang JW, Yang WS, Kim SB, Lee SK, Park SK, Park JS
- KMID: 2079749
- Korean J Nephrol.
- 2007 Jul;26(4):440-447.
PURPOSE: Low level of parathyroid hormone (PTH) is a risk factor that might cause hip fracture in dialysis patients. Low calcium dialysate (LCD) has been suggested as an approach to... -
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- Relationship Between Serum Magnesium and Parathyroid Hormone Levels in Hemodialysis Patients
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Ma SK, Kim JK, Park MJ, Park BS, Nah MY, Yeum CH, Kim SW, Kim NH, Kang YJ, Choi KC
- KMID: 1989900
- Korean J Nephrol.
- 2000 Nov;19(6):1071-1077.
The important factors involved in the regulation of PTH are calcium, vitamin D, and phosphorus. However, recent studies have suggested that magnesium may also play a significant role in the... -
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- The relationship between calcium sensing receptor gene (CA) polymorphism, bone mineral density and bone responsiveness to hormone replacement therapy in postmenopausal Korean women
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Kim JG, Ku SY, Jee BC, Suh CS, Kim SH, Choi YM, Moon SY
- KMID: 2272478
- Korean J Obstet Gynecol.
- 2004 Dec;47(12):2430-2438.
OBJECTIVE: To evaluate the relationship between the calcium sensing receptor (Casr) gene cytosine adenine (CA) polymorphism, bone mineral density (BMD) and bone responsiveness to hormone replacement therapy (HRT). METHODS: Casr (CA)... -
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- Calcium sensing receptor forms complex with and is up-regulated by caveolin-1 in cultured human osteosarcoma (Saos-2) cells
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Jung SY, Kwak JO, Kim HW, Kim DS, Ryu SD, Ko CB, Cha SH
- KMID: 755747
- Exp Mol Med.
- 2005 Apr;37(2):91-100.
The calcium sensing receptor (CaSR) plays an important role for sensing local changes in the extracellular calcium concentration ([Ca2+]o) in bone remodeling. Although the function of CaSR is known, the... -
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- The Effects of Extracellular pH on Proliferation and Differentiation of human Bone Marrow Stem Cells
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Leem YH, Nam TS, Kim JH, Lee KS, Lee DH, Yun J, Chang JS
- KMID: 1464234
- Korean J Bone Metab.
- 2012 May;19(1):35-46.
- doi: 10.11005/kjbm.2012.19.1.35
OBJECTIVES: The purpose of this study is to identify whether the change of pH affects the proliferation and the differentiation of human bone marrow stem cells (hBMSCs) and what mechanism... -
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- Relationship between the serum parathyroid hormone and magnesium levels in continuous ambulatory peritoneal dialysis (CAPD) patients using low-magnesium peritoneal dialysate
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Cho MS, Lee KS, Lee YK, Ma SK, Ko JH, Kim SW, Kim NH, Choi KC
- KMID: 2306120
- Korean J Med.
- 2001 Nov;61(5):527-536.
BACKGROUND: One of the most common complications in patients with end stage renal disease is renal osteodystrophy and parathyroid hormone (PTH) plays a key role in the pathogenesis of renal... -
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