- Early-Life Stress in D2 Heterozygous Mice Promotes Autistic-like Behaviors through the Downregulation of the BDNF-TrkB Pathway in the Dorsal Striatum
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Lee Y, Han PL
- KMID: 2451070
- Exp Neurobiol.
- 2019 Jun;28(3):337-351.
- doi: 10.5607/en.2019.28.3.337
A number of specific genetic variants including gene mutations and single nucleotide variations have been identified in genomewide association studies of autism spectrum disorder (ASD). ASD phenotypes in individuals carrying... -
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- Acute Stress and Chronic Stress Change Brain-Derived Neurotrophic Factor (BDNF) and Tyrosine Kinase-Coupled Receptor (TrkB) Expression in Both Young and Aged Rat Hippocampus
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Shi SS, Shao SH, Yuan BP, Pan F, Li ZL
- KMID: 1071416
- Yonsei Med J.
- 2010 Sep;51(5):661-671.
- doi: 10.3349/ymj.2010.51.5.661
PURPOSE: The purpose of this study is to explore the dynamic change of brain-derived neurotrophic factor (BDNF) mRNA, protein, and tyrosine kinase-coupled receptor (TrkB) mRNA of the rat hippocampus under... -
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- Effect of Brain-derived Neurotrophic Factor on Excitatory Synaptic Transmission in Hippocampal Neurons
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Song DK, Son EI, Hong YS, Bae JH, Park WK
- KMID: 1546027
- Korean J Aerosp Environ Med.
- 1999 Jun;9(2):192-197.
Brain-derived neurotrophic factor (BDNF) rapidly enhances synaptic transmission among the hippocampal neurons in the resting state. This mechanism may be due to the phosphorylation of NMDA receptors through its Trkb... -
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- Alpha-Asarone, a Major Component of Acorus gramineus, Attenuates Corticosterone-Induced Anxiety-Like Behaviours via Modulating TrkB Signaling Process
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Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2285510
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):191-200.
- doi: 10.4196/kjpp.2014.18.3.191
We investigated the anxiolytic-like activity of alpha-asarone (AAS) from Acorus gramineus in an experimental rat model of anxiety induced by repeated administration of the exogenous stress hormone corticosterone (CORT). The... -
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- Tyrosine Protein Kinase (trk) Receptors Expression in Malignant Melanoma Cells
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Lee JY, Park YL, Whang KU
- KMID: 2425606
- Korean J Dermatol.
- 1997 Dec;35(6):1151-1158.
BACKGROUND: Nerve growth factor(NGF), brain derived neurotrophic factor(BDNF), neurotropin 3(NT-3) and neurotropir-4/5 are neurotrophic factors necessary for the development and maintenance of specific neurors. The tyrosine protein kinase(trk) receptors exhibit... -
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- Early Motor Balance and Coordination Training Increased Synaptophysin in Subcortical Regions of the Ischemic Rat Brain
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Seo HG, Kim DY, Park HW, Lee SU, Park SH
- KMID: 1779235
- J Korean Med Sci.
- 2010 Nov;25(11):1638-1645.
- doi: 10.3346/jkms.2010.25.11.1638
The aim of this study was to evaluate the effect of early motor balance and coordination training on functional recovery and brain plasticity in an ischemic rat stroke model, compared... -
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