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A Case of Myeloid Neoplasm with a PDGFRB Rearrangement and Eosinophilia

Cho NG, Kim D, Shim M, Chong SY

Myeloid neoplasia with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) rearrangements is an uncommon Philadelphia-negative myeloproliferative neoplasm. Their most common morphological diagnosis is chronic myelomonocytic leukemia with eosinophilia, which...
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A case of myeloid neoplasm with the PDGFRB rearrangement and eosinophilia

Jang SE, Kang HJ, Chang YH, Lee DS, Kim HT, Koh KW, Yang SH

  • KMID: 2259192
  • Korean J Med.
  • 2010 Mar;78(3):386-390.
Myeloid neoplasm with the platelet-derived growth factor receptor beta (PDGFRB) rearrangement is a myeloproliferative neoplasm. Patients with this disease often have prominent eosinophilia or monocytosis and the presence of t(5;12)(q31~33;p12)...
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Myeloid and lymphoid neoplasm with eosinophilia and abnormalities of PDGFRB presenting as congestive heart failure and hypereosinophilia

Kwon JW, Kwon JH, Her AY

Hypereosinophilic syndrome (HES) is a heterogeneous disorder characterized by persistent hypereosinophilia with the evidence of organ dysfunction caused by eosinophilic involvement. HES can be induced by various secondary causes, including...
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A Case of Atypical Chronic Myeloid Leukemia with the JAK2V617F Mutation

Kim JY, Lee SR, Nam MH, Yoon SY, Lim CS, Lee CK, Kim BS, Cho Y, Kim YK, Lee KN

Atypical chronic myeloid leukemia (aCML) is a rare leukemic disorder that shows myelodysplastic and myeloproliferative features simultaneously. The Janus kinase 2 gene V617F mutation (JAK2V617F) in aCML has been the...
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