- Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model
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Tchah H, Youn DH, Holland EJ
- KMID: 1421510
- J Korean Med Sci.
- 1991 Mar;6(1):15-19.
- doi: 10.3346/jkms.1991.6.1.15
An orthotopic penetrating keratoplasty model was developed in the rat. An oversized (0.5 mm) graft was used and 8 interrupted sutures were applied. These sutures were not removed. Eleven grafts... -
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- Heterologous corneal endothelial cell transplantation: human corneal endothelial cell transplantation in Lewis rats
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Tchah H
- KMID: 1421935
- J Korean Med Sci.
- 1992 Dec;7(4):337-342.
- doi: 10.3346/jkms.1992.7.4.337
A heterologous corneal endothelial transplantation was attempted using human endothelial cells and a Lewis rat penetrating keratoplasty model. Cultured human endothelial cells were seeded to a Lewis rat cornea,... -
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- Increased expression of osteopontin in the spinal cords of Lewis rats with experimental autoimmune neuritis
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Moon C, Shin T
- KMID: 1093622
- J Vet Sci.
- 2004 Dec;5(4):289-293.
To investigate the pattern of expression of osteopontin (OPN) in tissues of the central nervous system (CNS) responding to peripheral immunological stimulation, the expression of OPN was studied in the... -
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- A Study of Serum HSP in Heart Transplanted Rats
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Lee HY, Kim JW, Yoo DW, Yoo CH, Son SH
- KMID: 2201872
- J Korean Soc Transplant.
- 2007 Dec;21(2):203-209.
PURPOSE: This study was performed to investigate the availability of the serum HSP72 and HSP27 as serologic markers of cardiac allograft rejection through rat heterotopic heart transplatation model. METHODS: Inbred... -
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- Effect of Fish Oil Diet on Activities of Lipogenic Enzymes and Glucose -6 -phosphatase in Rat Liver and Adipose
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Jung SE
- KMID: 1401868
- J Nurs Acad Soc.
- 1989 Dec;19(3):299-306.
In order to evaluate the effect of fish oil on lipid drogenase(G6PDH), malic enzyme (ME), glucose-6 -phosphatase (G6Pase) activities were measured in liver and adipose tissue of rats fed... -
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- Effect of Platelet-rich Plasma(PRP) on Regeneration of Rat Sciatic Nerve in a Silicone Chamber
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Minn KW, Jeong EC, Chang H, Kwon ST, Kim SW, Baek RM
- KMID: 2322224
- J Korean Soc Plast Reconstr Surg.
- 2010 Mar;37(2):105-109.
PURPOSE: The purpose of this study is to determine the effect of platelet-rich plasma(PRP) on rat sciatic nerve regeneration in a 10mm silicone chamber. METHODS: A total of 6 inbred Lewis... -
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- Increased expression of neuronal nitric oxide synthase in astrocytes and macrophages in the spinal cord of Lewis rats with autoimmune encephalomyelitis
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Shin T
- KMID: 1119215
- J Vet Sci.
- 2001 Dec;2(3):195-199.
Neuronal nitric oxide synthase (nNOS) is constitutively expressed in neurons of the central nervous system, where it plays a physiological role in neurotransmission. In this study, we examined the functional... -
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- Melatonin ameliorates autoimmune encephalomyelitis through suppression of intercellular adhesion molecule-1
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Kang JC, Ahn M, Kim YS, Moon C, Lee Y, Wie MB, Lee YJ, Shin T
- KMID: 1103513
- J Vet Sci.
- 2001 Aug;2(2):85-89.
Melatonin (N-acetyl-5-methoxytryptamine), a pineal neurohormone, is a hydroxyl radical scavenger and antioxidant, and plays an important role in the immune system. We studied the effect of exogenous melatonin on the... -
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- Vanishing Pancreatic Grafts
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Pivetti C, Hong IC, Yoo CH, Lee S, Kim K, Emmanuel G, Kim J, Chung R, Niewiadomski S, Wolf P, Gittes RF
- KMID: 1726185
- Yonsei Med J.
- 2004 Dec;45(6):1169-1172.
- doi: 10.3349/ymj.2004.45.6.1169
Comparison of pancreaticoduodenal transplants (PDT) and duct-ligated pancreas transplant (DLPT) were performed using syngeneic and allogeneic studies in rats. Both DLPT and PDT allogeneic grafts showed mild rejection. DLPT groups... -
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- Immunohistochemical Localization of Bcl-2 in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis
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Moon CJ, Lee YD, Shin TK
- KMID: 1097344
- J Vet Sci.
- 2002 Dec;3(4):279-283.
We examined the localization of the anti-apoptotic molecule Bcl-2 in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis (EAE). Western blot analysis showed that Bcl-2 was constitutively expressed... -
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- Expression of major histocompatibility complex antigen in Lewis rat cornea
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Tchah H
- KMID: 1735126
- Korean J Ophthalmol.
- 1994 Dec;8(2):66-71.
- doi: 10.3341/kjo.1994.8.2.66
Fresh rat corneas as well as corneas preserved in several different corneal preservation media were stained with Avidin-Biotin-peroxidase Complex method in order to evaluate major histocompatibility complex (MHC) antigen expression.... -
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- Increased phosphorylation of c-Jun NH (2)-terminal protein kinase in the sciatic nerves of Lewis rats with experimental autoimmune neuritis
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Ahn M, Shin T
- KMID: 1103547
- J Vet Sci.
- 2006 Mar;7(1):13-17.
- doi: 10.4142/jvs.2006.7.1.13
The phosphorylation of c-Jun NH (2)-terminal protein kinase (JNK), one of the mitogen-activated protein kinases, was analyzed in the sciatic nerves of Lewis rats with experimental autoimmune neuritis (EAN). Western... -
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- Embryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis
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Shin TK, Lee YD, Sim KB
- KMID: 1099815
- J Vet Sci.
- 2003 Apr;4(1):9-13.
Intermediate filaments, including nestin and vimentin, are found in specific cell types in central nervous system (CNS) tissues, particularly immature glial cells and multipotent progenitor cells. In the present study,... -
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- Immunopathogenesis of experimental melanin-protein induced uveitis
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Kim HS, Lee EH, Kim-Yoon S, Joo CK
- KMID: 1375106
- Korean J Ophthalmol.
- 1998 Jun;12(1):14-18.
- doi: 10.3341/kjo.1998.12.1.14
The etiology of uveitis, a general term for inflammatory disorders of the uveal tract, has not been clarified. The purpose of this study is to investigate the immunopathogenesis during experimental... -
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- A Novel Therapeutic Target in Inflammatory Uveitis: Transglutaminase 2 Inhibitor
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Sohn J, Chae JB, Lee SY, Kim SY, Kim JG
- KMID: 1098790
- Korean J Ophthalmol.
- 2010 Feb;24(1):29-34.
- doi: 10.3341/kjo.2010.24.1.29
PURPOSE: Our goal was to investigate the effects of inhibition of transglutaminase 2 (TGase 2) on endotoxin-induced uveitis (EIU) METHODS: EIU was induced in female Lewis rats by single footpad... -
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- Experimental autoimmune myasthenia gravis and CD5+ B-lymphocyte expression
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Lee KW, Lee SH, Kim HJ, Kim JM, Choi YM, Motomura M
- KMID: 1062201
- J Korean Med Sci.
- 1999 Feb;14(1):75-79.
- doi: 10.3346/jkms.1999.14.1.75
Myasthenia gravis is one of the typical organ specific autoimmune disease and the CD5+ B-lymphocytes are known to be associated with the secretion of autoimmune antibodies. The authors performed the... -
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- Stimulation of macrophage function by S-antigen: production of nitric oxide
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Bae SR
- KMID: 754267
- Korean J Ophthalmol.
- 2000 Jun;14(1):12-19.
- doi: 10.3341/kjo.2000.14.1.12
In this study, we investigated whether retinal soluble proteins, such as S-antigen, play a role in the induction of nitric oxide by macrophages in vitro. Cells from the murine macrophage... -
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- Stimulation of macrophage function by interphotoreceptor retinoid-binding protein: production of nitric oxide
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Bae SR
- KMID: 1127504
- Korean J Ophthalmol.
- 1999 Dec;13(2):57-64.
- doi: 10.3341/kjo.1999.13.2.57
In this study, we investigated whether retinal soluble proteins, such as interphotoreceptor retinoid-binding protein(IRBP), play a role in the induction of nitric oxide by macrophages in vitro. Cells from the... -
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- Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis
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Kim S, Moon C, Wie MB, Kim H, Tanuma N, Matsumoto , Shin T
- KMID: 1103469
- J Vet Sci.
- 2000 Jun;1(1):11-17.
To elucidate the role of nitric oxide synthase (NOS) in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), we analyzed the expression of constitutive neuronal NOS (nNOS), endothelial NOS (eNOS), and... -
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- Bilirubin protects grafts against nonspecific inflammation-induced injury in syngeneic intraportal islet transplantation
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Zhu H, Wang J, Jiang H, Ma Y, Pan S, Reddy S, Sun X
- KMID: 994397
- Exp Mol Med.
- 2010 Nov;42(11):739-748.
- doi: 10.3858/emm.2010.42.11.075
Nonspecific inflammatory response is the major cause for failure of islet grafts at the early phase of intraportal islet transplantation (IPIT). Bilirubin, a natural product of heme catabolism, has displayed... -
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