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Change of the Expression of Human Telomerase Reverse Transcriptase mRNA and Human Telomerase RNA after Cisplatin and 5-Fluorouracil Exposure in Head and Neck Squamous Cell Carcinoma Cell Lines

Lee BJ, Lee BH, Wang SG, Lee JC, Roh HJ, Goh EK, Kim CM, Jun ES

Telomerase activity appears to be associated with cell immortalization and malignant progression. Understanding how telomerase activity is regulated in vivo is important not only for understanding the molecular biology of...
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Aberrantly expressed microRNAs in the context of bladder tumorigenesis

Lee JY, Ryu DS, Kim WJ, Kim SJ

MicroRNAs (miRNAs), small noncoding RNAs 19-22 nucleotides in length, play a major role in negative regulation of gene expression at the posttranscriptional level. Several miRNAs act as tumor suppressors or...
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The role of microRNAs in bladder cancer

Enokida H, Yoshino H, Matsushita R, Nakagawa M

Bladder cancer (BC) is the fifth most common cancer worldwide and is associated with significant morbidity and mortality. The prognosis of muscle invasive BC is poor, and recurrence is common...
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Integrated analysis of copy number alteration and RNA expression profiles of cancer using a high-resolution whole-genome oligonucleotide array

Jung SH, Shin SH, Yim SH, Choi HS, Lee SH, Chung YJ

Recently, microarray-based comparative genomic hybridization (array-CGH) has emerged as a very efficient technology with higher resolution for the genome-wide identification of copy number alterations (CNA). Although CNAs are thought to...
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