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Ruxolitinib changes the natural course of myelofibrosis and its transplant outcome

Jung CW

No abstract available.
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Cardiovascular Safety of Celecoxib on Top of Dual Antiplatelet Therapy

Hong BK

No abstract available.
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Series with complete resolution of left atrial appendage thrombi with apixaban in elderly patients

Lee SH, Han S

No abstract available.
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New oral anticoagulants

Oh S

The most important and widely-prescribed drug for anticoagulation is a vitamin K antagonist such as warfarin although it has several limitations in clinical use. New oral anticoagulants (NOACs) have been...
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A Case of Celecoxib Induced Acute Generalized Exanthematous Pustulosis

Shin HT, Park SW, Lee KT, Park HY, Park JH, Lee DY, Lee JH, Yang JM, Lee ES

Acute generalized exanthematous pustulosis (AGEP) is manifested by rapid development of many sterile, nonfollicular pustules on a background of edematous erythema. More than 90 percent of AGEP are induced by...
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Simultaneous Closure of a Left Atrial Appendage through an Atrial Septal Defect and the Atrial Septal Defect

Song S, Lee OH, Kim JS, Cho IJ, Shim CY, Hong GR, Pak HN, Jang Y

Left atrial appendage (LAA) occlusion can be employed as an alternative treatment to oral anticoagulation in patients with atrial fibrillation to prevent embolic events. Atrial septal defect (ASD) may be...
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Anti-Obesity Drugs: A Review about Their Effects and Safety

Kang JG, Park CY

The current recommendations for the treatment of obese people include increased physical activity and reduced calories intake. When the behavioral approach is not sufficient, a pharmacologic treatment is recommended. In...
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Stroke Update 2011: New Antithrombotics

Seo KD, Lee KY

  • KMID: 2288709
  • Korean J Stroke.
  • 2012 Aug;14(2):62-66.
Several new antithrombotic drugs have been developed and approved to use in clinical practice recently. Dabigatran, a direct thrombin inhibitor, and rivaroxaban, a factor Xa inhibitor, have been approved in...
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A Case of Erythema Multiforme Induced by Celecoxib

  • KMID: 2234616
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Jun;29(2):138-141.
Celecoxib (Celebrex(R)) is a nonsteroidal anti-inflammatory drug (NSAID) which selectively inhibits cyclooxygenase (COX)-2. Celecoxib rarely induces serious cutaneous adverse reaction such as erythema multiforme, Steven-Johnson syndrome and toxic epidermal necrosis....
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A Novel Therapeutic Approach to Breast Cancer using a Selective Cyclooxygenase 2 Inhibitor and Adenovirus-mediated Delivery of the Melanoma Differentiationassociated Gene-7 (Ad-mda7)

Suh YJ, Hunt KK

Recently, many preclinical and clinical researches have focused on the possible roles of new therapeutic modalities to enhance current treatment efficacy or to extend the current limitations against breast cancer...
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The effects of Bendaline(R) on cataracts

Rhee SW, Youn DH, Lee L, Choi O, Jung HR

A double blind multicenter study of patients suffering from presenile and senile cataracts was performed, bendazac Iysine salt (Bendaline(R))or a placebo was administered orally to the patients and the results...
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Effect of preoperative administration of celecoxib on postoperative pain after laparoscopic cholecystectomy

Kim DY, An YM, Moon JP, Choi JG

BACKGROUND: For laparoscopic cholecystectomy, pain is most frequent complaint and the most common cause of delayed discharge. The aim of this study was to determine the effect of preoperative administration...
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Four Cases of Drug Allergy Caused by Non-Steroidal Anti-Inflammatory Drugs in Children

Park GM, Seo JH, Kim HY, Yu J, Hong SJ

  • KMID: 2315161
  • Pediatr Allergy Respir Dis.
  • 2011 Dec;21(4):344-349.
Acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs), which reduce the production of prostaglandin by inhibiting cyclooxygenase (COX), are widely used in children as antipyretic, analgesic, or anti-inflammatory drugs. They are known...
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Uncoventional Views on Certain Aspects of Toxin-Induced Metabolic Acidosis

Oh MS

This discussion will highlight the following 9 specific points that related to metabolic acidosis caused by various toxins. The current recommendation suggests that alcohol dehydrogenase inhibitor fomepizole is preferred to...
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Weight Loss Drugs Recently Approved by the FDA

Lee CB

There have been many advances in obesity treatment, including life-style modification and pharmacological and surgical treatments. It seems that the most remarkable advances in obesity treatment are those of pharmacological...
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Role of Estrogen Receptor-alpha in the Regulation of Claudin-6 Expression in Breast Cancer Cells

Yafang L, Qiong W, Yue R, Xiaoming X, Lina Y, Mingzi Z, Ting Z, Yulin L, Chengshi Q

PURPOSE: In our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17beta-estradiol induces a concentration- and time-related effect on CLDN6 mRNA...
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Synergistic effects of sorafenib and celecoxib inhibit growth and VEGF expression in Hec-1A endometrial cancer cell line

Kim JS, Park BR, Nam GH, Bae DH

OBJECTIVE: The aim of this study was to investigate whether combination of sorafenib and celecoxib exhibited an anti-tumor efficacy or altered expression of vascular endothelial growth factor (VEGF) in Hec-1A...
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The Cannabinoid Agonist WIN55,212-2 Suppresses Opioid-induced Pruritus in Mice

Lee H

  • KMID: 2263295
  • Anesth Pain Med.
  • 2008 Jul;3(3):167-171.
BACKGROUND: Cannabinoid receptor agonists can reverse opioidinduced nausea and vomiting in animals, but have not yet been tested against opioid-induced pruritus. This study tests the hypothesis that a cannabinoid receptor...
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Recent advances in the management of venous thromboembolism

Ageno W

Venous thromboembolism (VTE) is a spectrum of diseases that includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Anticoagulant treatment is the mainstay of therapy for VTE. Unfractionated heparin (UFH)...
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The Effect of a Topical Selective Cyclooxygenase-2 Inhibitor on Skin-Wound Scarring of the Rabbit Ear

Kim DY, Park JH, Chun BK, Han YS

  • KMID: 2322433
  • J Korean Soc Plast Reconstr Surg.
  • 2011 Jul;38(4):351-358.
PURPOSE: The inflammatory phase is considered an integral part of adult wound healing, but fetal wound healing studies have shown scarless healing results in the absence of the inflammation process....
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