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Procalcitonin as a biomarker of infectious diseases

Lee H

Traditional biomarkers, including C-reactive protein, leukocytes, erythrocyte sedimentation rate, and clinical signs and symptoms, are not sufficiently sensitive or specific enough to guide treatment decisions in infectious febrile diseases. Procalcitonin...
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PIVKA-II as a Serological Marker of Hepatocellular Carcinoma

Jeong SH

  • KMID: 760665
  • Korean J Hepatol.
  • 2006 Sep;12(3):315-317.
No abstract available.
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Procalcitonin and C-Reactive Protein in the Diagnosis and Prediction of Spontaneous Bacterial Peritonitis Associated With Chronic Severe Hepatitis B

Yuan LY, Ke ZQ, Wang M, Li Y

BACKGROUND: Procalcitonin (PCT), C-reactive protein (CRP), and white blood cells (WBCs) are inflammatory markers used to diagnose severe bacterial infections. We evaluated the diagnostic role of these markers and compared...
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Murine pro-tumor necrosis factor expressed in Saccharomyces cerevisiae HF7c localizes to membrane/particulate

Jeong JY, Jue DM

  • KMID: 1109303
  • Exp Mol Med.
  • 2000 Jun;32(2):61-66.
Tumor necrosis factor (TNF) is a cytokine that is produced by immune cells in response to bacterial and viral stimuli and plays important roles in various inflammatory diseases. TNF...
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Update on Procalcitonin Measurements

Meisner M

Procalcitonin (PCT) is used as a biomarker for the diagnosis of sepsis, severe sepsis and septic shock. At the same time, PCT has also been used to guide antibiotic therapy....
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The Expression of Human Beta Defensins by Thermal Injury

Jeong HS, Yeon CJ, Lee JS

  • KMID: 1439461
  • J Korean Burn Soc.
  • 2012 Jun;15(1):39-44.
PURPOSE: Defensins are important components of innate immune system. These peptides have antimicrobial activity against a wise variety of pathogens that associated with burn wound infection. In particular, human beta-defensins...
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Clinical Availability of Serum Procalcitonin in Children with Bacterical Infection

Noe EJ, Lee SY, Lee KM, Kim KN

  • KMID: 2072427
  • Korean J Pediatr Infect Dis.
  • 2010 Dec;17(2):108-113.
PURPOSE: The aim of this study was to identify clinical availability of serum procalcitonin (PCT) compared with C-reactive protein (CRP) in prediction of bacterial infection in children. METHODS: A retrospective study...
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Serum Pro-hepcidin as an Predictor of Iron Deficiency in Anemic Patients

Kim J, Son Y, Ihm C

BACKGROUND: Hepcidin has recently been known as a negative regulatory hormone of iron. Hepcidin precursor, pro-hepcidin has been used as a surrogate and reported to be related to iron deficiency....
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Clinical Usefulness of Serum Procalcitonin as a Biomarker of Acute Pyelonephritis

Yang EA, Park JS, Cho MH, Lee SW

  • KMID: 2080110
  • Korean J Nephrol.
  • 2010 Nov;29(6):716-724.
PURPOSE: The clinical usefulness of serum procalcitonin (PCT) was evaluated for the diagnosis of acute pyelonephritis (APN) in infants with urinary tract infections (UTIs). METHODS: A total of 46 infants (between...
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The Effects of Pre-emptive Administration of Ketamine and norBNI on Pain Behavior, c-Fos, and Prodynorphin Protein Expression in the Rat Spinal Cord after Formalin-induced Pain Is Modulated by the DREAM Protein

Long I, Suppian R, Ismail Z

BACKGROUND: We investigated the effects of pre-emptive administration of ketamine and norBNI on pain behavior and the expression of DREAM, c-Fos, and prodynorphin proteins on the ipsilateral side of the...
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Liver Transplantation for Advanced Hepatocellular Carcinoma

Lee KW, Suh KS

Hepatocellular carcinoma (HCC) has become an important indication for liver transplantation in Korea. Even though the Milan criteria have been accepted as the gold standard in deceased donor liver transplantation,...
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Comparison of Serum CRP and Procalcitonin in Patients after Spine Surgery

Chung YG, Won YS, Kwon YJ, Shin HC, Choi CS, Yeom JS

OBJECTIVE: Classical markers of infection cannot differentiate reliably between inflammation and infection after neurosurgery. This study investigated the dynamics of serum procalcitonin (PCT) in patients who had elective spine surgeries...
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The Utility of Serum Procalcitonin Levels in the Management of Systemic Inflammatory Response Syndrome in the Emergency Department

Park KH, Lee KH, Cha KC, Kim H, Hwang SO

BACKGROUND: The aim of this study was to investigate whether obtaining serum procalcitonin (PCT) levels in patients with systemic inflammatory response syndrome (SIRS) helps the differential diagnosis between sepsis and...
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Mean cell volumes of neutrophils and monocytes are promising markers of sepsis in elderly patients

Lee AJ, Kim SG

BACKGROUND: Sepsis in elderly patients is a major cause of morbidity and mortality in the clinical setting. The aim of this study was to assess the diagnostic significance of volume...
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The Usefulness of Procalcitonin and C-Reactive Protein as Early Diagnostic Markers of Bacteremia in Cancer Patients with Febrile Neutropenia

Kim DY, Lee YS, Ahn S, Chun YH, Lim KS

  • KMID: 2167555
  • Cancer Res Treat.
  • 2011 Sep;43(3):176-180.
PURPOSE: Procalcitonin (PCT) and C-reactive protein (CRP) are well known inflammatory markers. This study was designed to determine whether PCT and CRP are useful as early diagnostic markers for bacteremia...
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Usefulness of Serum Cortisol in Assessment for the Severity of Community-Acquired Pneumonia

Kim MS, Park HP, Yoon KH, Kim YJ, Kim MY, Kim EY, Bae MN, Bae SM

  • KMID: 2319455
  • Tuberc Respir Dis.
  • 2010 Dec;69(6):450-455.
BACKGROUND: High cortisol levels are frequently observed in patients with severe infections are of prognostic value in sepsis. The aim of this study was to evaluate the clinical usefulness of...
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Diagnostic Role of C-reactive Protein, Procalcitonin and Lipopolysaccharide-Binding Protein in Discriminating Bacterial-Community Acquired Pneumonia from 2009 H1N1 Influenza A Infection

Han SS, Kim SH, Kim WJ, Lee SJ, Ryu SW, Cheon MJ

  • KMID: 2319533
  • Tuberc Respir Dis.
  • 2011 Jun;70(6):490-497.
BACKGROUND: It is difficult but important to differentiate between bacterial and viral infections, especially for respiratory infections. Hence, there is an ongoing need for sensitive and specific markers of bacterial...
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Clinical Usefulness of Procalcitonin as Guideline of Antibiotic Treatment in Children with Respiratory Tract Infection

Lim HH, Kang HJ, Yang EA, Lee JH

  • KMID: 2315217
  • Pediatr Allergy Respir Dis.
  • 2012 Mar;22(1):110-115.
PURPOSE: Procalcitonin (PCT), a precursor of calcitonin, has been described as a biomarker of bacterial infection and inflammation. This study was performed to evaluate the clinical usefulness of PCT levels...
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Clinical Characteristics of Children with Lobar Pneumonia Caused by Mycoplasma pneumoniae

Yang EA, Gang MH, You SY, Kim JH, Lee JH

  • KMID: 2315272
  • Pediatr Allergy Respir Dis.
  • 2012 Sep;22(3):256-264.
PURPOSE: This study was conducted to evaluate the prevalence, clinical characteristics and laboratory findings of lobar pneumonia in children caused by Mycoplasma pneumonia and to find a diagnostic tool for...
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Prognostic Implications of Procalcitonin and NT-ProBNP in Febrile Neutropenic Patients

Kim SY, Park YR, Choi KV, Lee YH

  • KMID: 2049250
  • Clin Pediatr Hematol Oncol.
  • 2010 Apr;17(1):9-18.
PURPOSE: Procalcitonin and N-terminal brain natriuretic propeptide (NT-proBNP) has been increasingly used as an inflammatory marker to identify patients with systemic infection and future cardiac events. The aim of this...
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