- Characterizing affinity epitopes between prion protein and beta-amyloid using an epitope mapping immunoassay
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Kang M, Kim SY, An SS, Ju YR
- KMID: 2154253
- Exp Mol Med.
- 2013 Aug;45(8):e34.
Cellular prion protein, a membrane protein, is expressed in all mammals. Prion protein is also found in human blood as an anchorless protein, and this protein form is one of... -
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- CTCF as a multifunctional protein in genome regulation and gene expression
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Kim S, Yu NK, Kaang BK
- KMID: 2155420
- Exp Mol Med.
- 2015 Jun;47(6):e166.
- doi: 10.1038/emm.2015.33
CCCTC-binding factor (CTCF) is a highly conserved zinc finger protein and is best known as a transcription factor. It can function as a transcriptional activator, a repressor or an insulator... -
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- Does 3-O-Methyldopa(3-OMD) Inhibit the Binding of Levodopa to Plasma Protein
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Bae JW, Harder S
- KMID: 1554205
- Korean J Psychopharmacol.
- 1999 Oct;10(2):180-184.
OBJECTIVE: We determined the influence of 3-OMD in the protein binding of levodopa to estimate the effect of 3-OMD on the penetration of levodopa into brain. METHOD: P-glycoprotein in the brain... -
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- Nuclear protein binding patterns in the 5'-upstream regulatory elements of HLA class I genes
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Park JH, Kim JD, Kim SJ
- KMID: 1728914
- Yonsei Med J.
- 1994 Sep;35(3):295-307.
- doi: 10.3349/ymj.1994.35.3.295
The expression of MHC class I genes has been thought to be regulated by two major cis-acting regulatory elements. The first region, enhancer A (Enh A) spanning from positions -210... -
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- Neutrophilic Granule Protein Is a Novel Murine LPS Antagonist
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Hong J, Qu P, Wuest TR, Huang H, Huang C, Lin PC
- KMID: 2461198
- Immune Netw.
- 2019 Oct;19(5):e34.
- doi: 10.4110/in.2019.19.e34
Neutrophilic granule protein (NGP) was previously reported as a granular protein of neutrophils in mouse, but the function has not been known clearly. We found the presence of the possible... -
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- The functional domains of dopamine transporter for cocaine analog, CFT binding
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Lee SH, Chang MY, Jeon DJ, Oh DY, Son H, Lee CH, Lee YS, Lee YS
- KMID: 1093603
- Exp Mol Med.
- 2002 Mar;34(1):90-94.
Cocaine analogue, CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl) tropane) binding to dopamine transporter (DAT) in different species is quite heterogeneous. CFT is scarcely detected in bovine DAT whereas it is conspicuous in humans. To... -
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- The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein
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Park E, Choi Y, Ahn E, Park I, Yun Y
- KMID: 1009394
- Exp Mol Med.
- 2009 Oct;41(10):728-736.
- doi: 10.3858/emm.2009.41.10.079
The adaptor protein, LAD/TSAd, plays essential roles in T cell activation. To further understand the functions of this protein, we performed yeast two-hybrid screening using TSAd as bait and identified... -
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- Antigen-binding Characteristics of Circulating IgG Autoantibodies to Cytokeratin 18 Protein in Patients with Nonallergic Asthma
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Yim H, Kim JE, Shin JY, Ye YM, Park HS, Nahm DH
- KMID: 2157816
- J Korean Med Sci.
- 2006 Aug;21(4):652-655.
- doi: 10.3346/jkms.2006.21.4.652
Cytokeratin 18 (CK18) protein was identified as an airway epithelial cell autoantigen associated with nonallergic asthma. Cleavage of CK18 protein by caspase-3 is a marker of early apoptosis in epithelial... -
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- Identification of a putative cellular receptor 150 kDa polypeptide for porcine epidemic diarrhea virus in porcine enterocytes
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Oh JS, Song DS, Park BK
- KMID: 1089609
- J Vet Sci.
- 2003 Dec;4(3):269-275.
Porcine epidemic diarrhea virus (PEDV) causes an acute enteritis in pigs of all ages, often fatality for neonates. PEDV occupies an intermediate position between two well characterized members of the... -
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- A mechanism of differential expression of GLUT2 in hepatocyte and pancreatic beta-cell line
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Kim JW, Kim YK, Ahn YH
- KMID: 754982
- Exp Mol Med.
- 1998 Mar;30(1):15-20.
DNase I footprinting assay using liver nuclear extracts revealed six protected regions between nucleotide -600 and +110 and hence named Box I-VI. Upstream promoter element (UPE), a DNA element playing crucial role... -
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- Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulation
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Lee SJ, Lee JK, Maeng YS, Kim YM, Kwon YG
- KMID: 1123466
- Exp Mol Med.
- 2009 Mar;41(3):189-200.
- doi: 10.3858/emm.2009.41.3.022
Protein phosphatase-1 (PP1) nuclear targeting subunit (PNUTS), also called PP1R10, p99, or CAT 53 was originally isolated as a mammalian nuclear PP1-binding protein. In this study, we performed yeast two-hybrid... -
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- The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin
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Lin YP, Chang YF
- KMID: 1106228
- J Vet Sci.
- 2008 Jun;9(2):133-144.
- doi: 10.4142/jvs.2008.9.2.133
Adhesion through microbial surface components that recognize adhesive matrix molecules is an essential step in infection for most pathogenic bacteria. In this study, we report that LigB interacts with fibronectin... -
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- Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation
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Kim BY, Kim H, Cho EJ, Youn HD
- KMID: 1103590
- Exp Mol Med.
- 2008 Feb;40(1):71-83.
- doi: 10.3858/emm.2008.40.1.71
In this study, we investigated the role of Nur77, an orphan nuclear receptor, in HIF-alpha transcriptional activity. We found that Nur77 associates and stabilizes HIF-1alpha via indirect interaction. Nur77 was... -
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- An enzymatic method for the detection of human serum albumin
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Javed MU, Waqar SN
- KMID: 1085747
- Exp Mol Med.
- 2001 Jun;33(2):103-105.
Albumin is the most abundant protein in human serum. A dye-binding method is commonly used in clinical laboratories for its estimation using different types of dyes. However, all these dye... -
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- Chestnut as a Food Allergen: Identification of Major Allergens
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Lee SK, Yoon SH, Kim SH, Choi JH, Park HS
- KMID: 1712735
- J Korean Med Sci.
- 2005 Aug;20(4):573-578.
- doi: 10.3346/jkms.2005.20.4.573
Chestnut as a Food Allergen: Identification of Major Allergens To evaluate the clinical significance of chestnut as a food allergen in Korea, skin prick test and ELISA were done in... -
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- Transcription repression of a CCAAT-binding transcription factor CBF/HSP70 by p53
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Chae HD, Yun J, Shi D
- KMID: 1089459
- Exp Mol Med.
- 2005 Oct;37(5):488-491.
NF-Y transcription factor binds to CCAAT boxes on promoters of cell cycle regulatory genes such as cdc2, cyclin B, cdc25C, and cyclin A. We previously reported that the DNA binding... -
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- Pharmacokinetics, tissue residue and plasma protein binding of ofloxacin in goats
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Baruah H, Roy DC, Roy RK, Khonikor H
- KMID: 1120064
- J Vet Sci.
- 2004 Jun;5(2):97-101.
Ofloxacin was administered to six male goats intravenously (5 mg/kg) to determine its kinetic behavior, tissue residue, in vitro plasma protein binding and to compute a rational dosage regimen. The... -
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- A model for the reaction mechanism of the transglutaminase 3 enzyme
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Ahvazi B, Steinert P
- KMID: 1109310
- Exp Mol Med.
- 2003 Aug;35(4):228-242.
Transglutaminase enzymes (TGases) catalyze the calcium dependent formation of an isopeptide bond between protein-bound glutamine and lysine substrates. Previously we have shown that activated TGase 3 acquires two additional calcium... -
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- Cleavage of purified neuronal clathrin assembly protein (CALM) by caspase 3 and calpain
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Kim JA, Kim HL
- KMID: 1457537
- Exp Mol Med.
- 2001 Dec;33(4):245-250.
The most efficient means of protein internalization from the membrane are through clathrin-coated pits, which concentrate protein interactions with the clathrin-associated assembly protein complex AP-2 and internalization signals in the... -
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- Amyloid Precursor Protein Binding Protein-1 Is Up-regulated in Brains of Tg2576 Mice
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Yang HJ, Joo Y, Hong BH, Ha SJ, Woo RS, Lee SH, Suh YH, Kim HS
- KMID: 2285407
- Korean J Physiol Pharmacol.
- 2010 Aug;14(4):229-233.
- doi: 10.4196/kjpp.2010.14.4.229
Amyloid precursor protein binding protein-1 (APP-BP1) binds to the carboxyl terminus of amyloid precursor protein and serves as a bipartite activation enzyme for the ubiquitin-like protein, NEDD8. Previously, it has... -
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