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Environmental Risk Factors for Attention Deficit Hyperactivity Disorder and Implications for Clinical Practice

Kim JW

  • KMID: 2291689
  • J Korean Acad Child Adolesc Psychiatry.
  • 2011 Mar;22(1):10-15.
In this review, we have provided an overview of the environmental risk factors for attention deficit hyperactivity disorder (ADHD), focusing on the major environmental toxicants related to the disorder. Researchers...
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Environmental Pollution and Diabetes

Kim JH

Endocrine disrupting chemicals (EDCs) are exogenous chemicals contained in industrial substances and plasticizers commonly utilized worldwide. Human exposure to such chemicals, particularly at low-doses, is omnipresent, persistent, and occurs in...
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A Case of Chloracne Due to Exposure to Defoliating Agent During Vietnam war

Chong JH, Chon TH, Kim SC, Kim HY

  • KMID: 2230365
  • Korean J Dermatol.
  • 2000 Sep;38(9):1244-1247.
Chloracne is a refractory acneiform eruption due to halogenated polyaromatic compound(eg. dioxin, dibenzofurans, polychlorinated biphenyls, etc.). 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin, a kind of dioxin isomer, contained in the Agent Orange...
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Persistent Organic Pollutants and Obesity-Related Metabolic Dysfunction: Focusing on Type 2 Diabetes

Lee DH

  • KMID: 2424668
  • Epidemiol Health.
  • 2012;34:e2012002.
Even though obesity is a well-established risk factor of type 2 diabetes, there is emerging evidence that persistent organic pollutants (POPs), a variety of lipophilic chemicals accumulated in adipose tissue,...
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Endocrine Disruptors

Kang CG, Lee SH, Kim EK

For the previous century, the humans have created an unintended and unwanted problem of endocrine disruptors as a potential threat to our public health. By the name of industrialization, endocrine...
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Endocrine Disrupting Chemicals and Pubertal Development

Kim SH, Park MJ

During the past decades, advancement in pubertal onset especially in girls has been noticed worldwide. Genetic factors and increasing prevalence of adiposity may contribute, however ubiquitous presence of endocrine disrupting...
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Harmful Environmental Factors Leading to Attention-Deficit Hyperactivity Disorder

Kwon HJ, Ha M, Kim BN, Lim MH

Attention-deficit hyperactivity disorder (ADHD) is a common, childhood-onset, neuropsychiatric disorder with an estimated prevalence of 2–7.6% in Korean children. Although the etiology of ADHD is not well understood, evidence from...
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The Relationship between the Blood Level of Persistent Organic Pollutants and Common Gastrointestinal Symptoms

Kim HM, Youn CH, Ko HJ, Lee SH, Lee YM

BACKGROUND: Persistent organic pollutants (POPs) are toxic materials that cannot be broken down naturally and that easily accumulate in the body. Although several studies have attempted to reveal the effects...
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Effects of Polychlorinated Biphenyls on the Development of Neuronal Cells in Growth Period; Structure-Activity Relationship

Do Y, Lee DK

Polychlorinated biphenyls (PCBs) are accumulated in our body through food chain and cause a variety of adverse health effects including neurotoxicities such as cognitive deficits and motor dysfunction. In particular,...
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Chlorination of ortho-position on Polychlorinated Biphenyls Increases Protein Kinase C Activity in Neuronal Cells

Lee YJ, Yang JH

  • KMID: 1432247
  • Toxicol Res.
  • 2012 Jun;28(2):107-112.
Polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental pollutants. Recently, it is suggested that neurotoxic effects such as motor dysfunction and impairment in memory and learning have been associated with...
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Associations between Cigarette Smoking and Total Mortality Differ Depending on Serum Concentrations of Persistent Organic Pollutants among the Elderly

Lee YM, Bae SG, Lee SH, Jacobs DR, Lee DH

There are substantial variations of relative risks (RR) in smoking-related mortality by country and time. We hypothesized the RRs in smoking-related mortality might differ depending on serum concentrations of persistent...
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Effects of 3,3′,4,4′,5-pentachlorobiphenyl on human Kv1.3 and Kv1.5 channels

Kim JH, Hwang S, Park SI, Jo SH

Among the environmental chemicals that may be able to disrupt the endocrine systems of animals and humans are polychlorinated biphenyls (PCBs), a chemical class of considerable concern. PCB consists of...
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Ameliorative Effect of Palmiwon on Polychlorinated Biphenyl (PCB, Aroclor 1254)-Induced Spermiotoxicity in the Rat

Kim SD, Zhao Z, Kim CH, Jeong JG, Choi BR, Jung SY, Cho JH, Park JK

  • KMID: 2298744
  • Korean J Androl.
  • 2010 Aug;28(2):118-123.
PURPOSE: Polychlorinated biphenyls (PCBs, Aroclor 1254), synthetic chlorinated organic compounds, are known to decrease thyroid function, sperm count, and fertility, and increase the risk of testicular cancer; they may have...
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The Relationship between the Blood Level of Persistent Organic Pollutants and Common Gastrointestinal Symptoms

Kim HM, Youn CH, Ko HJ, Lee SH, Lee YM

BACKGROUND: Persistent organic pollutants (POPs) are toxic materials that cannot be broken down naturally and that easily accumulate in the body. Although several studies have attempted to uncover the effects...
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Effects of PCB Congeners in Rodent Neuronal Cells in Culture

Kim SY, Yang JH

  • KMID: 2285304
  • Korean J Physiol Pharmacol.
  • 2005 Feb;9(1):9-15.
We attempted to analyze the mechanism of polychlorinated biphenyl (PCB) -induced neurotoxicity and identify the target molecules in the neuronal cells for PCBs. Since the developing neuron is particularly sensitive...
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Continuous Exposure of Lactating Rat Mothers to Polychlorinated Biphenyls (PCBs) Increases Testis Volume, Sperm Production and Sertoli Cell Numbers in Adult Male Offspring

Kim IS, Yang HH, Cui CD

  • KMID: 2071851
  • Korean J Phys Anthropol.
  • 1999 Jun;12(1):159-168.
Despite the possible consequences of maternal ingestion of polychlorinated biphenyls (PCBs) on future generation, information in limited on how/whether maternal PCB exposure affects testis of the adult male offspring. Therefore,...
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Interaction Between Persistent Organic Pollutants and C-reactive Protein in Estimating Insulin Resistance Among Non-diabetic Adults

Kim KS, Hong NS, Jacobs DR, Lee DH

OBJECTIVES: Chronic inflammation is now thought to play a key pathogenetic role in the associations of obesity with insulin resistance and diabetes. Based on our recent findings on persistent organic...
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Adipose Tissue and Serum Levels of PCBs and DDE in Women with Gynecologic Benign Disease

Park SK, Lee KS, Rho YM, Koo JW, Min SY, Han JG, Ko WK, Kim MR, Chung JK, Lee JS, Kim JH

  • KMID: 2028087
  • Korean J Occup Environ Med.
  • 2000 Mar;12(1):81-92.
OBJECTIVES: This study was purposed to determine the levels of PCBs and DDE in adipose tissue and serum and to evaluate the relations with factors affecting these levels. METHODS: We...
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Early-life exposure to endocrine disrupting chemicals associates with childhood obesity

Yang C, Lee HK, Kong AP, Lim LL, Cai Z, Chung AC

Increasing prevalence of childhood obesity poses threats to the global health burden. Because this rising prevalence cannot be fully explained by traditional risk factors such as unhealthy diet and physical...
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Restoring one way traffic across the Roux loop: The Nakajo value

Rammohan A, Srinivas S, Al Azri Y, Reddy MS, Rela M

Roux-en-Y (RY) hepaticojejunostomy (HJ) is a critical component of complex hepatobiliary operations, and it is the treatment of choice for post-cholecystectomy biliary strictures (PCBS). Complications related to the Roux limb,...
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