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Myoclonus, Delayed Sequelae of Carbon Monoxide Poisoning, Piracetam Trial

Kim JS, Lee SA, Kim JS

One month following carbon monoxide poisoning, a 39 year-old man developed incontinence, memory impairment, disorientation and emotional instability. He was hospitalized 7weeks later, and during hospitalization he exhibited myoclonic movements...
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The Combination of Antidepressant Duloxetine with Piracetam in Mice does not Produce Enhancement of Nootropic Activity

Kale PP, Addepalli , Sarkar A, Patel S, Savai J

There is a strong association between depression and memory impairment. The present study aims to assess the nootropic activity of duloxetine and piracetam combination. Male Swiss Albino mice were divided...
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Effects of Long-Term Alcohol Treatment Combined with Vitamins or Piracetam on the Ultrastructure of Rat Hippocampal and Cerebellar Neurons

Sohn CH, Lee SI, Kwak JS, Jeong IW

  • KMID: 1899251
  • J Korean Soc Biol Psychiatry.
  • 2000 Nov;7(2):164-173.
This study was carried out to investigate the direct neurotoxicity of alcohol on CNS and the effects of piracetam or vitamins on ultrastructural changes of the rat cerebellar and hippocampal...
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A Case of Purpura Associated with Levetiracetam

Kim JA, Kim BN, Lee JH, Choi WJ, Shon JH, Lee SM, Choi HC

  • KMID: 2333420
  • J Korean Epilepsy Soc.
  • 2010 Jun;14(1):24-26.
Levetiracetam has not been reported to cause purpura. We report a case of purpura associated with levetiracetam. A 81-year-old man suffered from post-stroke seizure. Seizure was well controlled with valproate....
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Successful Treatment of Intractable Hiccup with Levetiracetam

Kim Y, Park H, Shin JH, Lee JH, Kim WK, Song HK

  • KMID: 2008770
  • J Korean Epilepsy Soc.
  • 2012 Jun;16(1):30-32.
Hiccups may be considered a form of myoclonus of diaphragm. Valproic acid has been considered the drug of choice in treatment of intractable hiccups; however, its various adverse events limit...
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Levetiracetam Monotherapy In Children with Epilepsy

Sim GY, Kim WS

  • KMID: 1442122
  • J Korean Child Neurol Soc.
  • 2011 Apr;19(1):26-32.
PURPOSE: Levetiracetam hasa been used in adjuvant therapy. It has also been used in monotherapy in other countries and therefore, we also studied the effect and efficacy of Levetiracetam monotherapy. METHODS:...
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Efficacy of levetiracetam in refractory childhood epilepsy

Lee KS, Kang JW

PURPOSE: To evaluate the efficacy and safety of levetiracetam adjunctive therapy for reducing the rate of seizure frequency in children with intractable pediatric epilepsy. METHODS: We reviewed the medical records of...
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The Effects of Antiepileptic Drugs on Balance in Older People

Lee GH

  • KMID: 2185061
  • J Korean Neurol Assoc.
  • 2008 Aug;26(3):186-193.
BACKGROUND: The purpose of this study was to quantitatively assess the subclinical balance dysfunction in elderly people taking antiepileptic drugs. METHODS: We recruited sixty-three patients who were at least 50 years...
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Dexmedetomidine and remifentanil in the perioperative management of an adolescent undergoing resection of pheochromocytoma: A case report

Jung JW, Park JK, Jeon SY, Kim YH, Nam SH, Choi YG, Bang SR

A 15-year-old adolescent with unilateral multiple adrenal pheochromocytoma had an episode of subcortical intracerebral hemorrhage and seizure 6 weeks before the surgery. He was pretreated with terazosin, losartan, atenolol and...
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Economic Evaluation of Add-on Levetiracetam for the Treatment of Refractory Partial Epilepsy in Korea

Suh GH, Lee SK

  • KMID: 2315836
  • Psychiatry Investig.
  • 2009 Sep;6(3):185-193.
OBJECTIVE: This study estimated the expected cost-effectiveness ratio expressed as the incremental cost per seizure-free day (SFD) gained and the incremental cost per quality adjusted life year (QALY) gained when...
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Clinical Experience with Levetiracetam Adjunctive Therapy for Pediatric Intractable Epilepsy

Park JS, Kang HC, You SJ

  • KMID: 2059403
  • J Korean Child Neurol Soc.
  • 2008 May;16(1):36-41.
PURPOSE: This study was designed to evaluate the safety and the reduction in seizure frequency of levetiracetam adjunctive therapy for pediatric epilepsy. METHODS: We retrospectively reviewed the medical records of 29...
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A Survey of the Use of Antiepileptic Drugs in Stroke Patients

Lee J, Jho W, Park PK, Kim J, Jang W, Kim HY, Kim YS, Kim HT, Kim J

  • KMID: 2343476
  • J Korean Neurol Assoc.
  • 2013 May;31(2):101-107.
BACKGROUND: Seizures occur in 2-20% of stroke patients. Recent studies have reported that post-stroke seizures are associated with poorer functional outcomesand higher mortality. However there are no official guidelines on...
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Efficacy and Safety of Levetiracetam in Children Younger than 4 Years with Intractable Epilepsy

Kim SH, Lim BC, Cho A, Chae JH, Hwang YS, Kim KJ

  • KMID: 1470047
  • J Korean Epilepsy Soc.
  • 2009 Jun;13(1):3-7.
PURPOSE: The aim of this study was to evaluate the efficacy and safety of levetiracetam in children younger than 4 years with intractable epilepsy. METHODS: A retrospective analysis of pediatric epilepsy...
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Increased EEG Current-Source Density in the High Beta Frequency Band Induced by Levetiracetam Adjunctive Therapy in Refractory Partial Epilepsy

Park SP, Kwon OY

BACKGROUND AND PURPOSE: Levetiracetam (LEV) is an antiepileptic drug (AED) that has favorable effects on cognition. Although neuropsychological studies have demonstrated these favorable outcomes on cognition, there are few electrophysiologic...
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Recent advances in the pharmacotherapy of psychiatric disorders

Woo YS, Bahk WM

  • KMID: 2342057
  • J Korean Med Assoc.
  • 2011 Oct;54(10):1061-1069.
Psychopharmacology has developed over approximately the past five decades. The remarkable proliferation of information in this area has made it difficult for clinicians to understand the characteristics of various psychotropic...
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A Case Report on Increased Aggression after Treatment with Levetiracetam

Kim SY, Kim JM, Kim SW, Park C, Shin IS, Jung TY, Yoon JS

  • KMID: 2287456
  • Korean J Psychopharmacol.
  • 2013 Apr;24(2):76-80.
Levetiracetam is a new antiepileptic drug that is used widely in Korea. It has reported behavioral side effects, most notably irritability, agitation, and aggressive behavior. However, these behavioral side effects...
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Effects of Idebenon (IBN-91) in Patients with Cerebrovascular diseases: Double Blind Placebo Controlled Study

Lee BI, Park SC, Huh JH, Choi YC, Lee BC, Lee HS, Kim MK, Nam JM, Chang SW

  • KMID: 1957297
  • J Korean Neurol Assoc.
  • 1994 Dec;12(4):652-665.
BACKGROUND: Although the clinical efficacy of nootropics for patients suffering from neurological deficits caused by cerebrovascular diseases (CVA) is still controversial, idebenon has been claimed to be quite useful for...
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The Effect of Combined Therapy of Exercise and Nootropic Agent on Cognitive Function in Focal Cerebral Infarction Rat Model

Song MK, Seon HJ, Kim IG, Han JY, Choi IS, Lee SG

OBJECTIVE: To investigate the effect of combined therapy of exercise and nootropic agent on cognitive function in a focal cerebral infarction rat model. METHOD: Forty 10-week old male Sprague-Dawley rats were...
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Psychiatric Symptoms and Quality of Life in Patients with Drug-Refractory Epilepsy Receiving Adjunctive Levetiracetam Therapy

Lee JJ, Song HS, Hwang YH, Lee HW, Suh CK, Park SP

BACKGROUND AND PURPOSE: Levetiracetam (LEV) is a new antiepileptic drug that has been found to be effective as an adjunctive therapy for uncontrolled partial seizures. However, the results of several...
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