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Cementless Press-Fit and Fibrous or Bony Ingrowth "Asian Total Hip Prosthesis" Design Using Computed Axial Tomography and Computer Aided Design and Computer Aided

Kim YH, Kim SJ, Kim WK, Park YP, Suh JS, Chung IH

The purpose of this study was to design intramedullary femoral stems that will optimally distribute the stresses to the bone. It was postulated that an ideal distribution of stresses would...
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Human Telomerase Reverse Transcriptase (hTERT): A Target Molecule for the Treatment of Cisplatin-resistant Tumors

Park YP, Kim KD, Kang SH, Yoon DY, Park JW, Kim JW, Lee HG

BACKGROUND: Human telomerase reverse transcriptase (hTERT) is a catalytic enzyme that is required for telomerase activity (TA) and cancer progression. Telomerase inhibition or inactivation increases cellular sensitivity to UV irradiation,...
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C-Terminal Serine Rich Region of IKK-beta Interacts with Bfl-1, a Homologue of Bcl-2

Yoon HK, Kim JK, Cho HJ, Cho MY, Park YP, You KH, Kim JW, Yoon DY, Choe YK, Lee HG

  • KMID: 2082800
  • Korean J Lab Med.
  • 2005 Jun;25(3):192-198.
BACKGROUND: Bcl-2 family proteins play a central role in regulating apoptosis. In human, over 20 members of this family have been identified to date. Bfl-1, a member of the Bcl-2...
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Modulation of Telomerase Activity and Human Telomerase Reverse Transcriptase Expression by Caspases and Bcl-2 Family Proteins in Cisplatin-Induced Cell Death

Park YP, Choi SC, Cho MY, Song EY, Kim JW, Paik SG, Kim YK, Kim JW, Lee HG

BACKGROUND: Human telomerase is a ribonucleoprotein polymerase, which synthesizes telomeric repeat sequences, and human telomerase reverse transcriptase (hTERT) has been identified as the catalytic subunit, as well as the rate-limiting...
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Cementless Bony lngrowth Total Hip Prosthesis (Anatomical Contact Porous Coated Total Hip Prosthesis) Design using Computed Axial Tomography and Computer Aid Design

Kim YH, Park YP, Suh JS

The purpose of this study is to design an Anatomical Contact Porous Coated Total Hip Prosthesis(ACP) which can transmit stress to the bone more physiologically and which can also eliminate...
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Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death

Choi SC, Yoon SR, Park YP, Song EY, Kim JW, Kim WH, Yang Y, Lim JS, Lee HG

  • KMID: 1091065
  • Exp Mol Med.
  • 2007 Dec;39(6):705-714.
Although N-myc downstream regulated gene 2 (NDRG2) has been known to be a tumor suppressor gene, the function of this gene has not been elucidated. In the present study, we...
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Role of STAT3 as a Negative Regulator in Mac2- Binding Protein Expression

Park YP, Kim JT, Yang Y, Lim JS, Yoon DY, Kim JW, Lee HG

BACKGROUND: Mac-2 binding protein (Mac-2BP) is a secreted glycoprotein from the culture fluid of several human cancer cells, especially breast, lung, and gastric cells. Mac-2BP plays a role in immune...
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