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Perspectives on Spinal Dysraphism : Past, Present, and Future

Pang D

This article recounts the author’s personal views and recollections of the history, conception of embryogenetic theories, application of intraoperative electrophysiology, and development of prospective treatment recommendations of several important spinal...
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Focal Spinal Nondisjunction in Primary Neurulation : Limited Dorsal Myeloschisis and Congenital Spinal Dermal Sinus Tract

Wong ST, Pang D

Spinal dysraphic lesions due to focal nondisjunction in primary neurulation are commonly encountered in paediatric neurosurgery, but the “fog-of-war” on these conditions was only gradually dispersed in the past 10...
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Junctional Neural Tube Defect

Eibach S, Pang D

Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and...
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Surgical Management of Complex Spinal Cord Lipomas : A New Perspective

Pang D

This review summarises the classification, anatomy and embryogenesis of complex spinal cord lipomas, and describes in some detail the new technique of total lipoma resection and radical reconstruction of the...
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Analysis of TRRAP as a Potential Molecular Marker and Therapeutic Target for Breast Cancer

Wang J, Shan M, Liu T, Shi Q, Zhong Z, Wei W, Pang D

PURPOSE: This study was designed to assess the protein levels of transformation/transcription domain-associated protein (TRRAP) in invasive ductal breast carcinomas, and investigated the association between TRRAP and the clinicopathological features...
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A novel panel of serum miR-21/miR-155/miR-365 as a potential diagnostic biomarker for breast cancer

Han JG, Jiang YD, Zhang CH, Yang YM, Pang D, Song YN, Zhang GQ

PURPOSE: Insufficient sensitivity and specificity prevent the use of most existing biomarkers for early detection of breast cancer. Recently, it was reported that serum microRNAs (miRNAs) may be potential biomarkers...
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