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Anti-inflammatory and Immunosuppressive Effects of Panax notoginseng

Cao TQ, Han JH, Lee HS, Ha MT, Woo MH, Min BS

Here, we designed to examine the anti-inflammatory effects on RAW264.7 cells and the immunosuppressive effects by evaluating interleukin-2 (IL-2) production in Jurkat T cells using a MeOH extract of Panax...
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Cognition enhancing effect of panax ginseng in Korean volunteers with mild cognitive impairment: a randomized, double-blind, placebo-controlled clinical trial

Park KC, Jin H, Zheng R, Kim S, Lee SE, Kim BH, Yim SV

This study aimed to investigate the cognition-enhancing effect of Panax ginseng. A randomized, double-blind, placebo-controlled clinical trial was conducted to address the cognition-enhancing effects of Panax ginseng. A total of...
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The Comparison of Seasonal Ginsenoside Composition Contents in Korean Wild Simulated Ginseng (Panax ginseng) which were Cultivated in Different Areas and Various Ages

Yang BW, Lee JB, Lee JM, Jo MS, Byun JK, Kim HC, Ko SK

The ginsenoside content was compared with wild simulated ginseng (Panax ginseng) collected every season at 11 wild simulated ginseng plantations in Korea. As a result, the total saponin of 7...
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Antiepileptic and anti-neuroinflammatory effects of red ginseng in an intrahippocampal kainic acid model of temporal lobe epilepsy demonstrated by electroencephalography

Kim JY, Kim JH, Lee HJ, Kim SH, Jung YJ, Lee HY, Kim HJ, Kim SY

BACKGROUND: Chronic inflammation can lower the seizure threshold and have influence on epileptogenesis. The components of red ginseng (RG) have anti-inflammatory effects. The abundance of peripherally derived immune cells in...
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Quantitative Analysis of Dammarane-type Ginsenosides in Different Ginseng Products

Lee DG, Quilantang NG, Lee JS, Geraldino , Kim HY, Lee S

Ginseng products available in different forms and preparations are reported to have varied bioactivities and chemical compositions. In our previous study, four new dammarane-type ginsenosides were isolated from Panax ginseng,...
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Protective effect of Korean red ginseng on oxaliplatin-mediated splenomegaly in colon cancer

Kang J, Park JS, Ahn SG, Lim JH, Baik SH, Yoon DS, Lee KY, Jeong J

PURPOSE: This study investigated how adding Korean red ginseng extract (KRG) to folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy affected the rate of splenomegaly in colon cancer. METHODS: This retrospective study...
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The Beneficial Effect of Korean Red Ginseng Extract on Atopic Dermatitis Patients: An 8 Weeks Open, Noncomparative Clinical Study

Kim H, Park CW, Cho SH

BACKGROUND: Atopic dermatitis (AD) is a chronic or chronically relapsing, eczematous, severely pruritic inflammatory skin disorder. Korean red ginseng (KRG) has been shown previously to exhibit diverse biological effects including...
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Optimization of Extraction Condition of Methyl Jasmonate-treated Wild Ginseng Adventitious Root Cultures using Response Surface Methodology

Liu Q, Jo YH, Ahn JH, Kim SB, Paek KY, Hwang BY, Park SY, Lee MK

The usage of wild ginseng (Panax ginseng C.A. Meyer) has been limited due to short supply and high price. Therefore, sufficient production as well as efficient extraction of mountain ginseng...
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Protective effects of cultured and fermented ginseng extracts against scopolamine-induced memory loss in a mouse model

Han SH, Kim SJ, Yun YW, Nam SY, Lee HJ, Lee BJ

This study was performed to investigate the effect of a concentrate of fermented wild ginseng root culture (HLJG0701) on memory improvement in the scopolamine (SPL)-induced memory-deficient mouse model. Eight-week-old male...
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Lipids in Ginseng (Panax ginseng) and Their Analysis

Kim SH, Kim SY, Choi HK

Ginseng (Panax ginseng) is recognized as one of the most valuable medicinal herbs in Asia and it contains diverse phytochemicals that contribute to its pharmacological effects. Although lipids represent a...
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Korean red ginseng excitation of paraventricular nucleus neurons via non-N-methyl-D-aspartate glutamate receptor activation in mice

Shen Y, Bhattarai , Park SJ, Lee GS, Ryu PD, Han SK

It has been reported that Korean red ginseng (KRG), a valuable and important traditional medicine, has varied effects on the central nervous system, suggesting its activities are complicated. The paraventricular...
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The Medicinal Usage and Restriction of Ginseng in Britain and America, 1660–1900

SUL H

This article demonstrates the medicinal usage of ginseng in the West from 1660 to 1914. Asian[Korea] ginseng was first introduced into England in the early 17th century, and North American...
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Antagonistic Evaluation of Chromobacterium sp. JH7 for Biological Control of Ginseng Root Rot Caused by Cylindrocarpon destructans

Han JH, Park GC, Kim KS

Cylindrocarpon destructans is an ascomycete soil-borne pathogen that causes ginseng root rot. To identify effective biocontrol agents, we isolated several bacteria from ginseng cultivation soil and evaluated their antifungal activity....
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The Effect of Fungicides on Mycelial Growth and Conidial Germination of the Ginseng Root Rot Fungus, Cylindrocarpon destructans

Shin JH, Fu T, Park KH, Kim KS

Ginseng root rot caused by Cylindrocarpon destructans is the most destructive disease of ginseng. Six different fungicides (thiophanate-methyl, benomyl, prochloraz, mancozeb, azoxystrobin, and iprodione) were selected to evaluate the inhibitory...
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Effect of P. ginseng on the expression of c-Fos in the brain of Wistar rats with testosterone induced benign prostatic hyperplasia

Jang HM

The lower urinary tract symptoms (LUTS) show in benign prostatic hyperplasia (BPH). The three major micturition centers in brain are pontine micturition center (PMC), ventrolateral periaqueductal gray (vlPAG), and medial...
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From Woohwang Cheongsimwon (牛黃淸心元) to Ginseng (人蔘): The History of Medicine Use in the Joseon Era

KIM SS

In Korean traditional medicine, though herbal decoction, acupuncture, and moxibustion are all used to treat diseases, restorative medicines are the most widely preferred treatment method. This paper explores the historical...
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Blood flow-improving activity of methyl jasmonate-treated adventitious roots of mountain ginseng

Ban YH, Cha Y, Choi J, An ES, Lee JY, Han NR, Seo DW, Jung G, Jeong DH, Rhee MH, Choi EK, Kim YB

Ginsenosides from Panax ginseng are well known for their diverse pharmacological effects including antithrombotic activity. Since adventitious roots of mountain ginseng (ARMG) also contain various ginsenosides, blood flow-improving effects of...
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Synergetic Hepatoprotective Effects of Korean Red Ginseng and Pueraria Radix on the Liver Damaged-Induced by Carbon Tetrachloride (CClâ‚„) in Mice

Hwang SH, Wang Z, Kang IJ, Lim SS

This study was designed to investigate the synergetic hepatoprotective effects from a mixture of Korean Red Ginseng and Pueraria Radix on carbon tetrachloride (CClâ‚„)-induced hepatotoxicity in mice. Liver toxicity was...
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Panax Ginseng Induces Toxic Hepatitis and Acute Kidney Injury

Lee JH, Yoon JH, Kim SS, Ma SK, Kim SW, Bae EH

No abstract available.
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Control Efficacy of Streptomyces sp. A501 against Ginseng Damping-off and Its Antifungal Substance

Van Minh N, Woo EE, Lee GS, Ki DW, Lee IK, Lee SY, Park K, Song J, Choi JE, Yun BS

Ginseng damping-off, caused by the fungal pathogens Rhizoctonia solani and Pythium sp., is a critical disease in ginseng seedling. In a continuing effort to find microorganisms with the potential of...
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