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Stimulation of macrophage function by S-antigen: production of nitric oxide

Bae SR

In this study, we investigated whether retinal soluble proteins, such as S-antigen, play a role in the induction of nitric oxide by macrophages in vitro. Cells from the murine macrophage...
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Decreased nitric oxide synthesis in rats with chronic renal failure

Kim SW, Lee JU, Paek YW, Kang DG, Choi KC

The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept...
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Stimulation of macrophage function by interphotoreceptor retinoid-binding protein: production of nitric oxide

Bae SR

In this study, we investigated whether retinal soluble proteins, such as interphotoreceptor retinoid-binding protein(IRBP), play a role in the induction of nitric oxide by macrophages in vitro. Cells from the...
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The distribution of nitric oxide synthase in human corpus cavernosum on various impotent patients

Choi YD, Mah SY, Xin ZC, Choi HK

Recent evidence implicates NO (Nitric oxide) as the principal mediator in an erection. To investigate the role of NO in the human erectile function, we studied the distribution...
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Altered renal expression of nitric oxide synthase isozymes in spontaneously hypertensive rats

Kim SW, Moon KH, Lee SC, Kim NH, Kang DG, Lee JU, Choi KC, Kang YJ

  • KMID: 759080
  • Korean J Intern Med.
  • 1999 Jan;14(1):21-26.
OBJECTIVES: The present study was aimed at exploring whether the pathogenesis of hypertension is related with an altered expression of nitric oxide synthase (NOS) isozymes, i.e., bNOS, iNOS...
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Nitrous oxide synthase expression in placenta of preeclampsia

Lee CN, Chang SW, Cho NH, Cho SH

To compare the expression of endothelial nitrous oxide synthase (e-NOS), which plays a major role in vasoconstriction, in preeclampsia with that in the normotensive placenta and to identify whether...
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The Role of Nitric Oxide in Experimental Cerulein Induced Pancreatitis

Um SH, Kwon YD, Kim CD, Lee HS, Jeen YT, Chun HJ, Lee SW, Choi JH, Ryu HS, Hyun JH

An enhanced formation of nitric oxide(NO), due to the induction of inducible nitric oxide synthase(iNOS), has been implicated in the pathogenesis of shock and inflammation, but its role in acute...
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Assessment of urinary endothelin-1 and nitric oxide levels and their relationship with clinical and pathologic types in primary glomerulonephritis

Duan SB, Liu FY, Luo JA, Peng YM

To determine the relationship between the urinary endothelin (ET-1), nitric oxide (NO) levels and the clinical, pathologic types of primary glomerulonephritis (GN) patients, urinary levels of ET-1 and NO were...
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Role of nitric oxide in penile erection

Jung HC, Mun KH, Park TC, Lee YC, Park JM, Huh K, Seong DH, Suh JK

The present study was undertaken to investigate the role of nitric oxide (NO) in erectile physiology by correlating its action with the existence and activity of nitric oxide synthase (NOS),...
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Erythropoietin does not affect nitric oxide system in rats with chronic renal failure

Kim SW, Lee JU, Kang DG, Jung K, Kim NH, Suh SP, Choi KC, Kang YJ

We investigated to see whether an altered role of nitric oxide (NO) system is involved in erythropoietin (EPO)-induced hypertension in chronic renal failure (CRF). Male Sprague-Dawley rats were five-sixths nephrectomized...
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The effects of oxygen radicals on the activity of nitric oxide synthase and guanylate cyclase

Kim SM, Byun JS, Jung YD, Kang IC, Choi SY, Lee KY

  • KMID: 755012
  • Exp Mol Med.
  • 1998 Dec;30(4):221-226.
Reactive oxygen species such as superoxides, hydrogen peroxide (H2O2) and hydroxyl radicals have been suggested to be involved in the catalytic action of nitric oxide synthase (NOS) to produce NO...
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Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage

Han MK

  • KMID: 1097262
  • Exp Mol Med.
  • 2003 Apr;35(2):136-139.
Cytokines produced by immune cells infiltrating pancreatic islets have been implicated as one of the important mediators of beta-cell destruction in insulin-dependent diabetes mellitus. In this study, the protective effects...
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Differentially-altered vascular guanylate cyclase isoforms in experimental hypertensive rats

Lee JU, Kang DG, Kook H, Kim IK, Oh BS

Pathophysiological implications of the vascular nitric oxide (NO)/cGMP pathway were investigated in various rat models of hypertension. The expression of brain and endothelial constitutive NO synthases (bNOS, ecNOS) was determined...
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Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population

Park JE, Hwang TH, Chu JA, Kim S, Choi YH, Lee SH, Seo JD, Lee WR, Lee WH

  • KMID: 759492
  • Korean J Intern Med.
  • 2000 Jan;15(1):65-70.
OBJECTIVES: The aging process affects responsiveness and other functions of endothelium and vascular smooth muscle cells, predisposing the old vessels to the development of atherosclerotic lesions. Endothelial nitric oxide synthase ...
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NF-kappa B decoy potentiates the effects of radiation on vascular smooth muscle cells by enhancing apoptosis

Zhang SY, Park KW, Oh S, Cho HJ, Cho HJ, Park JS, Cho YS, Koo BK, Chae IH, Choi DJ, Kim HS, Lee MM

  • KMID: 1033097
  • Exp Mol Med.
  • 2005 Feb;37(1):18-26.
NF-kappa B promotes cell survival against external stress such as radiation. We examined whether NF-kappa B decoy transfection enhances the antiproliferative effects of radiation on vascular smooth muscle cells (VSMCs)...
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