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Stress-Induced Atherosclerosis: Clinical Evidence and Possible Underlying Mechanism

Chung IM

There is increasing recognition in medical fields of the importance of behavioral and psychosocial factors in the development of cardiovascular disease. Although the pathogenesis underlying stress-induced atherosclerosis is not well...
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Potential Mechanisms Underlying the Increased Excitability of the Bladder Afferent Pathways in Interstitial Cystitis/Bladder Pain Syndrome

Kim DS

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic debilitating disorder associated with lower urinary tract symptoms, including frequency, urgency, and suprapubic pain, which inconveniences the patients and seriously impairs their...
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A Role of Nitric Oxide in the Enhancement of Neurogenic Inflammation with Capsaicin-Rechallenge in the Rat Nasal Mucosa

Ma YW, Jeon SY, Kim JP, Ahn SK

  • KMID: 2275995
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Feb;46(2):115-119.
BACKGROUND AND OBJECTIVES: The role of neurogenic inflammation in the airways appears to protect the airways from various irritants in the inspired air. Enhanced NO production by inducible NO synthase...
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The Role and Localization of Nitric Oxide Synthasein Neurogenic Inflammation of the Rat Airways

Shim JJ, Lee SY, Lee SH, Suh JK, Cho JY, Kim CH, In KH, Yoo SH, Kang KH

BACKGROUND: There have been many debates about the effects of nitric oxide on the neurogenic inflammation. The role of nitric oxide in the neurogenic inflammation of airways will be required...
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Capsaicin-induced Mast Cell Activation

Chai OH, Rhee SO, Han EH, Lee MS

  • KMID: 2092664
  • Korean J Anat.
  • 1998 Aug;31(4):629-635.
Capasicin, a neurotoxin extracted from red peppers, has selective effects on peptide-containing C-fiber and induces the release of neuropeptides from sensory nerve endings. Mast cells and neuropeptide-containing nerve fibers occur...
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Effect of Endogenous Nitric Oxide on Neurogenic Plasma Extravasation in Nasal Mucosa of Rat

Lee HM, Choi CS, Song JJ, Lee SH

  • KMID: 2274633
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Feb;43(2):159-163.
BACKGROUND AND OBJECTIVES: Nitric oxide is a labile neurotransmitter causing vasodilation by relaxing vascular smooth muscle. Endogenous nitric oxide is an important modulator of airway function, but its role in...
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Influence of Cortex mori on the Capsaicin-induced Neurogenic Inflammation

Yoon CY, Shin DW, Hong CM, Lee WK, Jang DD, Chai OH, Kang KJ, Lee MS

  • KMID: 2224588
  • Korean J Anat.
  • 1999 Feb;32(1):1-9.
The root bark of mulberry (Morus alba L. Cortex Mori and other plant of the genus Morus) has been used as an antiphlogistic, diuretic, and expectorant in herbal medicine, and...
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The Present and Future of Prostatitis

Cho IR

  • KMID: 2311976
  • Korean J Urol.
  • 2008 Jun;49(6):475-489.
Prostatitis is a common disease that is confusing and frustrating for urologists. Chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS) is the most common form of prostatitis. The etiology of CP/CPPS is unknown,...
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The Effect of Lumbar Sympathetic Block in Interstitial Cystitis: A case report

Jung JY, Jung JW, Kim YI

Interstitial cystitis is an extremely painful and distressing condition, characterized by severe suprapubic pain, which increases with bladder filling and is relieved by voiding. The daily frequency of micturition may...
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Enhancement of Microvascular Leakage in the Nasal Mucosa after Re-exposure to Capsaicin in a Rat Model Challenged/Rechallenged with Capsaicin

Jeon SY, Kim EA, Sung JH, Kim JP, Jung TG, Hwang EG

  • KMID: 2131772
  • J Rhinol.
  • 2000 Nov;7(2):123-126.
It has been suggested that the role of neurogenic inflammation is to protect the airway from various noxious irritants in inhaled air. Repeated exposure to various irritating stimuli has become...
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Complex Regional Pain Syndrome Type I after Stroke

Shin JH

Complex regional pain syndrome (CRPS) is a chronic painful, limb-confined condition with autonomic and inflammatory characteristics. Although the exact cause is still poorly understood, facilitated neurogenic inflammation, pathologic sympathetic-afferent coupling,...
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Vital tooth with periapical lesion: spontaneous healing after conservative treatment

Kim HJ, Lee SJ, Jung IY, Park SH

  • KMID: 2316818
  • Restor Dent Endod.
  • 2012 May;37(2):123-126.
It is often presumed that apical periodontitis follows total pulp necrosis, and consequently root canal treatment is commonly performed. Periapical lesion development is usually caused by bacteria and its byproduct...
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Chronic Prostatitis/Chronic Pelvic Pain Syndrome: What Are the Starting and Worsening Factors?

Chung H

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in the absence of any identifiable pathology such as cancer, curable infection, or anatomic abnormalities is defined as "urologic pain or discomfort in the...
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The Actions of Sodium Valproate in Headache model Evoked by Substance-P in rats.

Han JK, Park MK, Park KW, Lee DH

  • KMID: 1546744
  • J Korean Neurol Assoc.
  • 1998 Feb;16(1):1-7.
BACKGROUND AND PURPOSE: Valproic acid (2-propylpentanoic acid) which enhances GABA synthesis and blocks it's degradation has been useful treatment of migraine and may activate GABA receptors to modulate trigeminal nociceptive...
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Neurogenic Inflammation Induced by Hypertonic Saline in Rat Nasal Mucosa

Lee HM, Lee SH

  • KMID: 1922565
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Mar;40(3):402-408.
The purpose of this study was to investigate whether inhaled hypertonic aerosols could increase vascular permeability in the rat nasal mucosa which was mediated by the release of sensory neuropeptides....
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Local application of NK1 receptor antagonists and pulpal blood flow in cat

Kim YK, Chu WS, Lee HJ, Ahn DK, Yoo HM, Kim SK

The purpose of this study was to investigate the influence of NK1 receptor antagonists on the pulpal blood flow (PBF) when applied iontophoretically through the dentinal cavity of the teeth...
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Effects of FK224, a NK1 and NK2 Receptor Antagonist, on Plasma Extravasation of Neurogenic Inflammation in Rat Airways

Shim JJ, Lee SY, Lee SH, Park SM, Seo JK, Cho JY, In KH, Yoo SH, Kang KH

BACKGROUND: Asthma is an inflammatory disease because there are many inflammatory changes in the asthmatic airways. Axon reflex mechanisms may be involved in the pathogenesis of asthma. Sensory neuropeptides are...
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A proposal of injection points of botulinum toxin into temporal region for chronic migraine

Kim YG, Bae JH, Kim ST

Botulinum toxin (BoNT) injections have been used not only in the field of cosmetic surgery such as forehead and eye wrinkle treatment but also in the treatment of chronic migraine,...
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Inhibitory effect of Cortex mori on the substance P-induced mast cell degranulation, granular leukocyte infiltraion, and vascular permeability in vivo

Chai OH, Jung SH, Lee MS

  • KMID: 2092640
  • Korean J Anat.
  • 1998 Feb;31(1):53-61.
Cortex mori (Morus alba L.), the root bark of mulberry tree, has been used as an antiphlogistic, diuretic, and expectorant in herbal medicine. It has been reported tha hot water...
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Regulation of pulpal microcirculation by calcitonin gene-related peptide

Kim SK, Kim YK, Jin MU

The purpose of this study was to investigate the function of calcitonin gene-related peptide (CGRP) in regulatory mechanism of pulpal microcirculation with the aim of elucidating neurogenic inflammation. Experiments were performed...
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