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The Inhibitory Effect of Propofol on Splenocytes Proliferations to Lipopolysaccharide in BALB/c Mice: Based on the Measurement of BrdU Incorporation in vitro

You JH, Song HK, Jeong DC, Ryu KH, Chin YS

BACKGROUND: Anesthetics have been suspected of impairing various aspects of the immune function either directly by affecting the function of immunocompetent cells or indirectly by modulating the stress response. Splenocytes...
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Marker-Genes for Dioxin-Induced Hematopoietic Stem Cell Dysfuction Using the Oligonucleotide-Microarray in Mice

Lee EJ, Jung IH, Kim HL

To develop the biomarkers for the immune dysfunction induced by dioxin, 2, 3, 7, 8-TCDD was administered C57BL/6N mice 0.1microg TCDD/??body weight. Colony forming assay showed that the proliferation potential...
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Proteomics of Protein Expression Profiling in Tissues with Different Radiosensitivity

An JH, Kim J, Seong J

  • KMID: 2198577
  • J Korean Soc Ther Radiol Oncol.
  • 2004 Dec;22(4):298-306.
PURPOSE: The purpose of this study was to identify Radiosensitivity of proteins in tissues with different radiosensitivity. MATERIALS AND METHODS: C3H/HeJ mice were exposed to 10 Gy. The mice were...
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Molecular Detection of Spirometra decipiens in the United States

Jeon HK, Park H, Lee D, Choe S, Sohn WM, Eom KS

The genus Spirometra belongs to the family Diphyllobothriidae and order Pseudophyllidea, and includes intestinal parasites of cats and dogs. In this study, a plerocercoid labeled as Spirometra mansonoides from the...
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Identity of Spirometra theileri from a Leopard (Panthera pardus) and Spotted Hyena (Crocuta crocuta) in Tanzania

Eom KS, Park H, Lee D, Choe S, Kang Y, Bia MM, Ndosi BA, Nath TC, Eamudomkarn C, Keyyu J, Fyumagwa R, Mduma S, Jeon HK

In the present study, a Spirometra species of Tanzania origin obtained from an African leopard (Panthera pardus) and spotted hyena (Crocuta crocuta) was identified based on molecular analysis of cytochrome...
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Effects of chronic alcohol and excessive iron intake on mitochondrial DNA damage in the rat liver

Park JE, Lee JR, Chung J

PURPOSE: In this study, we investigated the effects of chronic alcohol and excessive iron intake on mitochondrial DNA (mtDNA) damage and the progression of alcoholic liver injury in rats. METHODS: Twenty-four...
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Molecular Differentiation of Opisthorchis viverrini and Clonorchis sinensis Eggs by Multiplex Real-Time PCR with High Resolution Melting Analysis

Kaewkong W, Intapan PM, Sanpool O, Janwan P, Thanchomnang T, Laummaunwai P, Lulitanond V, Doanh PN, Maleewong

Opisthorchis viverrini and Clonorchis sinensis are parasites known to be carcinogenic and causative agents of cholangiocarcinoma in Asia. The standard method for diagnosis for those parasite infections is stool examination...
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Pediatric-Onset Dystonia Associated with Bilateral Striatal Necrosis and G14459A Mutation in a Korean Family: A Case Report

Kim IS, Ki CS, Park KJ

We describe a Korean family presenting with pediatric-onset, progressive, generalized dystonia with bilateral striatal necrosis and the homoplasmic G14459A mutation in the mitochondrial ND6 gene. The G14459A mutation has been...
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Genome-wide hepatic DNA methylation changes in high-fat diet-induced obese mice

Yoon A, Tammen SA, Park S, Han SN, Choi SW

BACKGROUND/OBJECTIVES: A high-fat diet (HFD) induces obesity, which is a major risk factor for cardiovascular disease and cancer, while a calorie-restricted diet can extend life span by reducing the risk...
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Analysis of Usefulness of Biochemical Enzyme Assay and MR Spectroscopy(MRS) in Leigh Syndrome

Choi BH, Robinson B, Kim JH, Kim HM, Choi CK, Yoo HW, Ko TS

  • KMID: 2177130
  • J Korean Child Neurol Soc.
  • 1998 May;5(2):319-327.
PURPOSE: Leigh syndrome is a kind of mitochondrial disease with a pathological production of lactate and variable clinical manifestations. Recently biochemical assay of the mitochondrial enzyme activity and MRS are...
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Activation domain in P67phox regulates the steady state reduction of FAD in gp91phox

Han CH, Lee MH

  • KMID: 1103471
  • J Vet Sci.
  • 2000 Jun;1(1):27-31.
An activation domain in p67(phox) (residues 199-210) is critical for regulating NADPH oxidase activity in cell-free system [10] To determine the steady state reduction of FAD, thioacetamide-FAD was reconstituted in...
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