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Effects of ketamine on contractile responses in vascular smooth muscle

Kang BS, Lee YH, Nam TS, Yeon DS, Hwng SK, Park KS

This study was designed to determine the effects of ketamine on contractions induced by norepinephrine (NE), K+ or histamine (Hist) and on agonist-induced calcium mobilization, in rabbit thoracic aorta with...
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Methionine Enhances the Contractile Activity of Human Colon Circular Smooth Muscle In Vitro

Choe EK, Moon JS, Park KJ

Effective drug to manage constipation has been unsatisfactory. We sought to determine whether methionine has effect on the human colon. Human colon tissues were obtained from the specimens of colon...
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Inhibitory Effects of Potassium Channel Blockers on Carbachol-induced Contraction in Rat Detrusor Muscle

Oh SJ, Ahn SC

We present accidental findings that potassium channel blockers, such as tetraethyl-ammonium (TEA) or 4-aminopyridine (4-AP), inhibit the sustained tonic contraction induced by carbachol in rat detrusor muscle strips. The relatively...
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Effects of Polyamines on Contractility of Guinea-Pig Gastric Smooth Muscle

Kim YC, Sim JH, Kim YH, Kwon SC, Lee SJ, Kim SR, Kim DW, Park SM, Youn SJ, Lee SJ, Xing DG, Xu WX, Kim KW

This study was designed to investigate the effects of polyamines on mechanical contraction and voltage-dependent calcium current (VDCC) of guinea-pig gastric smooth muscle. Mechanical contraction and calcium channel current (I(Ba))...
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