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The Influence of Bcl-3 Expression on Cell Migration and Chemosensitivity of Gastric Cancer Cells via Regulating Hypoxia-Induced Protective Autophagy

Hu L, Bai Z, Ma X, Bai N, Zhang Z

PURPOSE: Gastric cancer is a highly metastatic malignant tumor, often characterized by chemoresistance and high mortality. In the present study, we aimed to investigate the role of B-cell lymphoma 3...
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Cytocompatibility and cell proliferation evaluation of calcium phosphate-based root canal sealers

Mestieri L, Zaccara IM, Pinheiro L, Barletta F, Kopper PM, Grecca FS

OBJECTIVES: This study aimed to evaluate the cell viability and migration of Endosequence Bioceramic Root Canal Sealer (BC Sealer) compared to MTA Fillapex and AH Plus. MATERIALS AND METHODS: BC Sealer,...
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Full mouth rehabilitation using removable prosthesis of patient with unstable mandible movements: A case report

Sohn DH, Yi YJ, Jo DW

Patients with collapsed occlusal support and unilateral chewing show parafunctional mandibular movements, which can be complicated in older patients. Gothic arch tracing and split cast technique are used to confirm...
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Comparison of inclination and vertical changes between single-wire and double-wire retraction techniques in lingual orthodontics

Hung BQ, Hong M, Yu W, Kyung HM

OBJECTIVE: The Heat Induction Typodont System (HITS), used in some recent studies, has a distinct advantage over previous tooth movement simulation methods. This study aimed to compare inclination and vertical...
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Horizontal ridge augmentation using guided bone regeneration technique in two young patients with localized alveolar ridge defect: A case report

Kim DH, Jeong SN

Lateral ridge augmentation using guided bone regeneration technique is a frequently performed procedure that is used for restoring localized bone defects after extraction. In particular, demineralized bovine bone material and...
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Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury

Hwang K, Jung K, Kim IS, Kim M, Han J, Lim J, Shin JE, Jang JH, Park KI

Spinal cord injury (SCI) causes axonal damage and demyelination, neural cell death, and comprehensive tissue loss, resulting in devastating neurological dysfunction. Neural stem/progenitor cell (NSPCs) transplantation provides therapeutic benefits for...
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Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes

Cui HS, Cho YS, Joo SY, Mun CH, Seo CH, Kim JB

BACKGROUND: Low temperature plasma (LTP) was recently shown to be potentially useful for biomedical applications such as bleeding cessation, cancer treatment, and wound healing, among others. Keratinocytes are a major...
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Case series of cleidocranial dysplasia: Radiographic follow-up study of delayed eruption of impacted permanent teeth

Yeom HG, Park WJ, Choi EJ, Kang KH, Lee BD

This report describes 3 cases of cleidocranial dysplasia (CCD) and presents relevant findings on long-term follow-up radiographic images of impacted permanent teeth with delayed eruption. Radiographic images of 3 CCD...
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Diagnostic Challenges Associated with GLUT1 Deficiency: Phenotypic Variabilities and Evolving Clinical Features

Kim H, Lee JS, Lee Y, Kim SY, Lim BC, Kim KJ, Choi M, Chae JH

GLUT1 deficiency is a rare neurometabolic disorder that can be effectively treated with ketogenic diet. However, this condition is underdiagnosed due to its nonspecific, overlapping, and evolving symptoms with age....
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Type of tooth movement during en masse retraction of the maxillary anterior teeth using labial versus lingual biocreative therapy in adults: A randomized clinical trial

Sadek MM, Sabet NE, Hassan IT

OBJECTIVE: The objective of this two-arm parallel trial was to compare the type of tooth movement during en masse retraction of the maxillary anterior teeth using labial versus lingual biocreative...
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The influence of leukocyte-platelet-rich plasma on accelerated orthodontic tooth movement in rabbits

Nakornnoi , Leethanakul C, Samruajbenjakun B

OBJECTIVE: To determine the effects of a local injection of leukocyte-platelet-rich plasma (L-PRP) on orthodontic tooth movement in rabbits. METHODS: Twenty-three male New Zealand white rabbits were included in a split-mouth...
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Three-dimensional analysis of tooth movement in Class II malocclusion treatment using arch wire with continuous tip-back bends and intermaxillary elastics

Lee JY, Choi SK, Kwon TH, Kang KH, Kim SC

OBJECTIVE: The aim of this study was to analyze three-dimensional (3D) changes in maxillary dentition in Class II malocclusion treatment using arch wire with continuous tip-back bends or compensating curve,...
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Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors

Kim TH, Custodio R, Cheong JH, Kim HJ, Jung YS

Luteolin, a widespread flavonoid, has been known to have neuroprotective activity against various neurologic diseases such as epilepsy, and Alzheimer’s disease. However, little information is available regarding the hypnotic effect...
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Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells

Zhu SM, Park YR, Seo SY, Kim IH, Lee ST, Kim SW

BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide...
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Clinical Milestones Preceding the Diagnosis of Multiple System Atrophy and Progressive Supranuclear Palsy: A Retrospective Cohort Study

Wiblin L, Durcan R, Galna B, Lee M, Burn D

OBJECTIVE: Multiple System Atrophy (MSA) and progressive supranuclear palsy (PSP) are rapidly progressive forms of degenerative Parkinsonism. The difficulties of diagnosing MSA and PSP in their early stages may lead...
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Oro-Pharyngeal Dysphagia in Parkinson's Disease and Related Movement Disorders

Kwon M, Lee JH

Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson's disease (PD) and related disorders, even in their early stage of diseases. Dysphagia in these patients has been underdiagnosed, probably...
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Intrusion of the extruded maxillary central incisor using skeletal anchorage system and unilateral segmental intrusion arch

Kwon EY, Baek YJ, Park SB, Kim SS, Kim YI, Choi YK

Patients who have a moderate periodontitis with pathologic tooth migration of maxillary incisors, it is necessary not only periodontal treatment for reduce periodontal inflammation, but also orthodontic treatment to teeth...
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Pseudo-Single Umbilical Artery by Spontaneous Intrauterine Umbilical Artery Thrombosis

Baik M, Im SY, Lee G

Umbilical artery thrombosis is rare event and few prenatally diagnosed cases have been reported. Antenatal diagnosis is very critical, as it is associated with high risk of perinatal motility and...
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HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice

Kim T, Song S, Park Y, Kang S, Seo H

Parkinson’s disease (PD) is one of the late-onset neurodegenerative movement disorder. Major pathological markers of PD include progressive loss of dopaminergic neurons, Lewy body formation, genetic mutations, and environmental factors....
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Evaluation of hematologic profile may be needed for patients treated with oxcarbazepine

Jung GH, You SJ

PURPOSE: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the...
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