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The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis

Moon YA

Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance, obesity, and dyslipidemia. NAFLD encompasses a wide range of states from the simple accumulation of triglycerides in the hepatocytes...
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Dance Intervention Using the Feldenkrais Method Improves Motor, and Non-Motor Symptoms and Gait in Parkinson’s Disease: A 12-Month Study

Kang SH, Kim J, Kim I, Moon YA, Park S, Koh SB

Objective The aim of this study was to assess the effects of dancing (using the Feldenkrais method) on motor and non-motor symptoms, quality of life (QoL), and objective parameters of...
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Simple Purification of Adeno-Associated Virus-DJ for Liver-Specific Gene Expression

Liu J, Moon YA

Recombinant gene expression using adeno-associated viruses (AAVs) has become a valuable tool in animal studies, as they mediate safe expression of transduced genes for several months. The liver is a...
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Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter

Moon YA, Park SW, Kim KS

  • KMID: 1093599
  • Exp Mol Med.
  • 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist...
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Expression and localization of human papillomavirus type 16 E6 and E7 open reading frame proteins in human epidermal keratinocyte

Kim KH, Yoon DJ, Moon YA, Kim YS

Over 60 different types of human papillomavirus (HPV) have been identified, and they are classified into high and low risk groups based on the risk for malignant progression of HPV...
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Characterization of regulatory elements on the promoter region of human ATP-citrate lyase

Moon YA, Kim KS, Cho UH, Yoon DJ, Park SW

  • KMID: 1029940
  • Exp Mol Med.
  • 1999 Jun;31(2):108-114.
ATP-citrate lyase (ACL), an enzyme catalyzing the first step in biosynthesis of fatty acids, is induced during the lipogenesis and cholesterologenesis. We demonstrate that the region -213 to -128 of human ACL...
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Regulation of ATP-citrate lyase gene transcription

Kim KS, Kang JG, Moon YA, Park SW, Kim YS

It has been suggested that glucose metabolites and insulin are the most important factors inducing ATP-citrate lyase (ACL) by a high carbohydrate diet. We have used a primary culture of...
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