- The Pharmacological Inhibition of ERK5 Enhances Apoptosis in Acute Myeloid Leukemia Cells
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Kang C, Kim JS, Kim CY, Kim EY, Chung HM
- KMID: 2429555
- Int J Stem Cells.
- 2018 Nov;11(2):227-234.
- doi: 10.15283/ijsc18053
Acute myeloid leukemia (AML) is a fatal hematological malignancy which is resistant to a variety of chemotherapy drugs. Extracellular signal-regulated kinase 5 (ERK5) plays a novel role in chemoresistance in... -
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- Laminar flow activation of ERK5 leads to cytoprotective effect via CHIP-mediated p53 ubiquitination in endothelial cells
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Lim JH, Woo CH
- KMID: 1447440
- Anat Cell Biol.
- 2011 Dec;44(4):265-273.
- doi: 10.5115/acb.2011.44.4.265
Atherosclerosis is readily observed in areas where disturbed flow is formed, while the atheroprotective region is found in areas with steady laminar flow (L-flow). It has been established that L-flow... -
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