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A Case of Mycosis Fungoides Treated with Photochemotherapy (PUVA)

Kim YK, Kim JS, Rhim KJ, Son SJ

  • KMID: 1678632
  • Korean J Dermatol.
  • 1982 Dec;20(6):931-937.
A 68-year-old male patient who was diagnosed as cutaneous mycosis fungoides with plaques, nodules and tumor has been treated with photochemotherapy. Oral methoxsalen followed by ultraviolet light(PUVA) resulted in clinical...
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Treatment of Witiligo with Oral Methoxsalen and UVA

Park YK, Park HY

  • KMID: 2231636
  • Korean J Dermatol.
  • 1985 Oct;23(5):643-649.
Among ]20 vitiligo patients who visited our clinic during the period of January 1984 to February 1985, 39 patients were treated with oral methoxsalen (8-MOP) and UVA for more than...
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PUVA Therapy of Pityriasis Lichenoides Chronica

Han HK, Kim JK, Kook HI

  • KMID: 1678494
  • Korean J Dermatol.
  • 1982 Jun;20(3):413-417.
Pityriasis lichenoides chronica is characterized by unknown etiology, chronicity and by being essentially asymptomatic and refractory to therapy. Nine patients with pityriasis lichenoides chronica were treated with orally administrated 8-Methoxypsoralen...
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Photoallergic Dermatitis due to 8-Methoxypsoralen

Choi HJ, Hann SK, Park YK, Chin SH

One adverse effect of PUVA therapy is the development of severe dermatitis. Only a few cases of photoallergy to psoralens during PUVA therapy have been reported. We describe herein a...
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Photochemotherapy of Vitiligo with Topical Methoxsalen and longwave ultraviolet light

Yoon JI, Suh WS, Lee MH, Lim SD

  • KMID: 1678449
  • Korean J Dermatol.
  • 1982 Apr;20(2):221-230.
Vitiligo is a common acquired Thypornelanotic disease but the pathogenesis is still unknown and also the traatment is still unsatisfactory. The introduction in 1947 of psoralen therapy in vitiligo by...
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Effect of 8-methoxypsoralen on PHA-induced DNA synthesis of human lymphocyte in the absence of UVA

Chung JH, Kim KH, Youn JI, Ree JH

  • KMID: 2230897
  • Korean J Dermatol.
  • 1992 Oct;30(5):601-607.
We have observed the dark effect of 8-methoxypsoralen (8-MOP) on the viability and DNA synthesis in human lymphocyte cultures after stimulation with phytohemagglutinin (PHA) in the absence of ultraviolet A...
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Inflammatory skin response to photochemotherapy: ear swelling response in C57BL mouse model

Ree JH, Youn JI

  • KMID: 2230898
  • Korean J Dermatol.
  • 1992 Oct;30(5):608-615.
We have observed the dark effect of 8-methoxypsoralen(8-M(P) on the viability and DNA synthesis in human lymphocyte cultures after stimulaticn with phytohemagglutinin (PHA) in the absence of ultraviolet A radiation....
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Studies on the Effects of Various Topical Phototoxic Drugs and UVA on Melanocytes of C57 BL Mice

Park YK, Kim YC, Hann SK, Cho MY, Koo SW

One hundred sixteen C57 BL mice were painted with either 8-MOP, 5-MOP or TMP solution in concentrations of 0.02%, 0.1%, and 0.5% each and UVA irradiated. Skin biopsies were performed...
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Epidermal Changes with Ultraviolet Irradiation and PUVA Treatment in the Black Mouse

Han KW, Han HK, Myung KB, Kook HI

  • KMID: 2231549
  • Korean J Dermatol.
  • 1986 Oct;24(5):586-593.
The pretent study was performed to study the epiderrnal changes of ultraviolet irradiation and PUVA treatment in the black mice. The following results were obtained: 1) The histologic changes of...
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Effects of 8 - Methoxypsoralen ( 8 - MOP ) on the Proliferation and Melanization of Cultured Normal Human Melanocytes without UVA

Lee MH, Yoo HD, Park JK, Haw CR

  • KMID: 1930762
  • Korean J Dermatol.
  • 1994 Oct;32(5):832-837.
BACKGROUND: Psoralen has been used in the treatment of certain hypojigmentary disorders with UVA or solar irradiation. However trecent report proposed the actions of psiralens are direct and do not...
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Study on the Development of a Rapid Detection Method for Pathogenic Yersinia enterocolitica and Yersinia pseudotuberculosis by Nested Polymerase Chain Reaction

Oh HJ, Min HK, Sohn YW, Hong SH

  • KMID: 1943432
  • J Korean Soc Microbiol.
  • 1999 Apr;34(2):175-187.
A nested polymerase chain reaction (PCR) was applied to detect and identify pathogenic Yersinia enterocolitica and Y. pseudotuberculosis. We used photochemical postamplification procedure with 8-methoxypsoralen to control carryover contamination. Using...
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Allergic contact dermatitis due to 8-methoxypsoralen(8-MOP)

Lee IJ, Park YK, Im S, Hann SK

  • KMID: 2128364
  • Korean J Dermatol.
  • 1992 Dec;30(6):897-900.
Allergic contact dermatitis due to 8-MOP is a rarely known si(ie effect of this widely used drug. Other known adverse reactions due to 8-MOP such as the oallergic dermatitis as...
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A Study on the Minimal Phototoxic Dose (MPD)

Kim YS, Park JK

  • KMID: 2085581
  • Korean J Dermatol.
  • 1986 Feb;24(1):16-21.
In order to measure the MPD with 8-methoxypsoralen, we selected 49 Korean healthy male vlunteers without phototoxic or photosensitive dermatoses. They were divided to 3 groups (Immediate; group 1, 1...
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The effects of PUVA on epidermal melanocytes in C57BL mice

Ree JH, Youn JI

  • KMID: 2303598
  • Korean J Dermatol.
  • 1992 Aug;30(4):484-491.
The object of this study is to evaluate the effects of repeat,ed PUVA applications on epidermal melanocytes. The changes in the number of melanocyes is compared to the frequency of...
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Photochemotherapy for Psoriasis

Choi CS, Kim EJ, Son SJ

  • KMID: 1677780
  • Korean J Dermatol.
  • 1978 Dec;16(6):449-457.
The beneficial effects of sunlight and ultraviolet light for the treatment, of psoriasis vulgaris has long been recognized. Parrish et al were the first to introduce a controlled light source,...
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Comparison of Local Bath-PUVA with Steroid Treatment in Palmoplantar Pustular Psoriasis and Dyshidrotic Eczema

Kim J, Choi YW, Choi HY, Myung KB

  • KMID: 1568197
  • Korean J Dermatol.
  • 2000 Jun;38(6):742-749.
BACKGROUND: Local bath-PUVA(LB-PUVA) therapy has been recently tried for the treatment of palmoplantar pustular psoriasis and chronic eczema with successful results. However it has not been reported that the effectiveness...
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Minimal Phototoxic Dose for Vitiliginous Skin Lesions

Kim H, Park JK, Seo YJ, Lee JH

  • KMID: 2302852
  • Korean J Dermatol.
  • 2004 Aug;42(8):983-987.
BACKGROUND: Photochemotherapy (PUVA) is the effective treatment for vitiligo. It is necessary to measure the minimal phototoxic dose (MPD) in order to ascertain a safe, effective UVA dose needed for...
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A Study for A New Method for Evaluation of Phototoicity

Park HC, Moon KC, Kim SN

  • KMID: 2085637
  • Korean J Dermatol.
  • 1988 Oct;26(5):629-635.
The present study was carried out to find a simple and safe in. vitro test for phtotoxic drugs. Authors selected two strains of Salmonella typhimurium(TA98 and TA102) which have been...
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Study of the Minimal Erythema Dose and Minimal Melanogenic Dose of UVA - 1 and Minimal Phototoxic Dose of UVA - 1 and UVA - 2 in Young Adult Koreans

Kim YK, Chae YS, Suh KS, Kim ST

  • KMID: 2230711
  • Korean J Dermatol.
  • 1996 Feb;34(1):71-77.
BACKGROUND: Minimal erythema dose(MED), minimal melanogenic dose (MMD) and minimal phototoxic dose(MPD) of UVA-1 in Koreans has not been determined, although MED and MMD of UVB and MPD of UVA-2...
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Effect of PUVA on Nerve Growth Factor Expression in Cultured Keratinocytes

Lee MH, Kim HJ, Lee JW, Kim YI

  • KMID: 2285263
  • Korean J Physiol Pharmacol.
  • 2002 Oct;6(5):275-279.
Nerve growth factor (NGF) is an important autocrine growth factor and also a survival factor for keratinocytes. NGF may act in the hyperproliferative condition, psoriasis. Clinically, the combination of psoralen...
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