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Four cases of Stevens-Johnson Syndrome associated with Methazolamide Treatment

Ahn EY, Lee JB, Lee SC, Won YH

  • KMID: 1568222
  • Korean J Dermatol.
  • 2000 Jun;38(6):798-801.
Methazolamide is a carbonic anhydrase inhibitor commonly used for lowering intraocular pressure in glaucoma and other ophthalmologic diseases. Carbonic anhydrase inhibitors are sulfonamide derivatives that are known to cause many...
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Epidermal Necrolysis due to Methazolamide Treatment in Glaucomatous Patients

Kim MS, Choi H, Shin BS, Choi KC

  • KMID: 1451634
  • Korean J Dermatol.
  • 2011 Jun;49(6):533-537.
Epidermal necrolysis (EN) is a rare, but potentially life threatening disease, characterized by epidermal necrosis and sub-epidermal detatchment, and is predominantly medication-induced. Methazolamide is a sulfonamide derivative and carbonic anhydrase...
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Two Cases of HLA-B59(+) Stevens-Johnson Syndrome (SJS)-Toxic Epidermal Necrolysis (TEN) Associated with Methazolamide Treatment

Sung KH, Jeong Y, Choi HU, Lee SK

  • KMID: 2302664
  • Korean J Dermatol.
  • 2005 Apr;43(4):561-563.
Methazolamide is a sulfonamide derivative and carbonic anhydrase inhibitor used to lower intraocular pressure in glaucomatous eyes. Stevens-Johnson syndrome (SJS)-toxic epidermal necrolysis (TEN) associated with methazolamide treatment has been reported...
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Five Cases of Stevens-Johnson Syndrome May Be Associated with Methazolamide Treatment

Han G, Yoon SD, Lee KS, Cho JW

  • KMID: 1427467
  • Korean J Dermatol.
  • 2013 May;51(5):329-334.
Recently, Stevens-Johnson syndrome associated with methazolamide has been reported in Koreans, more frequently. Methazolamide is a carbonic anhydrase inhibitor commonly used for lowering intraocular pressure in glaucoma and other ophthalmologic...
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Three Cases of Stevens-Johnson Syndrome Associated with Methazolamide Treatment

Park YJ, Moon JI, Park CK

  • KMID: 2336810
  • J Korean Ophthalmol Soc.
  • 1999 Feb;40(2):613-618.
There have been recent reports on the increasing number of Stevens-Johnson syndrome cases resulting from methazolamide and its relatively higher incidence in Japanese and Korean than any other people. The...
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A Case of Methazolamide- and Acetazolamide-Induced Asthma

  • KMID: 2090097
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Jun;24(2):261-264.
Acetazolamide and methazolamide are carbonic anhydrase inhibitors commonly used for lowering intraocular pressure in glaucoma and other ophthalmic diseases. They are unsubstituted sulfonamide derivatives that are known to cause many...
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Association of HLA Type with Stevens-Johnson Syndrome Induced by Methazolamide Treatment

Moon JI, Seo JH, Park CK

  • KMID: 2127757
  • J Korean Ophthalmol Soc.
  • 2000 Oct;41(10):2241-2246.
There have been reports between Stevens-Johnson syndrome (SJS)induced by methazolamide treatment and genetic background especially in Japanese and Korean descent.We report 6 cases of SJS and the results of HLA...
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Methazolamide-induced Stevens-Johnson Syndrome

Seo YS, Chang KC, Chang MH

PURPOSE: To report three consecutive cases of methazolamide-induced Stevens-Johnson syndrome. CASE SUMMARY: We describe three patients who were all prescribed methazolamide for treatment of ophthalmologic conditions. A 29-year-old man and a...
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Angle Closure and the Acute Rise of Intraocular Pressure after Administration of Methazolamide

Jeong KD, Kim B, Oh WH

PURPOSE: To report a case involving an unexpected increase in intraocular pressure (IOP) and acute angle closure after oral administration of methazolamide. CASE SUMMARY: A 38-year-old male visited the emergency department...
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Methazolamide-induced toxic epidermal necrolysis confirmed by lymphocyte activation test

Han KH, Hong KH, Kim DH, Kim YS, Park JS, Kim SH, Jee YK

Among various dermatological entities, toxic epidermal necrolysis (TEN) is a rare but potentially fatal delayed hypersensitivity reaction to numerous medications. A 38-year-old male presented with systemic hypersensitivity reaction, such as...
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Comparison of Methazolamide and Acetazolamide for Prevention of Acute Mountain Sickness in Adolescents

Lee JH, Choi PC

  • KMID: 2332985
  • J Korean Soc Emerg Med.
  • 2011 Oct;22(5):523-530.
PURPOSE: Acute mountain sickness (AMS) commonly occurs when unacclimatized individuals ascend to altitudes above 2500 m. Acetazolamide, a carbonic anhydrase inhibitor (CAI), is recommended for AMS prophylaxis, but may have...
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A Case of Paclitaxel-induced Maculopathy Treated with Methazolamide

Koo NK, Kim YC

A 54-year-old female patient who had been undergoing anti-cancer chemotherapy and radiotherapy for seven years after surgery for left breast cancer visited our clinic for visual disturbance in the right...
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A Case of Stevens-Johnson Syndrome Caused by Acetazolamide

Ha JH, Song JY, Kim HO, Kim JW

  • KMID: 2303040
  • Korean J Dermatol.
  • 2003 Feb;41(2):248-250.
A 53-year-old man having glaucoma treated with acetazolamide. After 7 days, he developed diffuse erythematous papules on both forearms and hands with multiple erosive lesions on his lips and genitalia....
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Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome Caused by Topical Ophthalmic Use of Dorzolamide

Kim JW, Shin SY

  • KMID: 2247975
  • Korean J Dermatol.
  • 2009 Mar;47(3):317-321.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the potentially life-threatening, acute hypersensitivity reaction to inciting drugs. These diseases have been often associated with systemic carbonic anhydrase inhibitor such...
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Genetic markers of severe cutaneous adverse reactions

Jung JW, Kim JY, Park IW, Choi BW, Kang HR

Adverse drug reactions can cause considerable discomfort. They can be life-threatening in severe cases, requiring or prolonging hospitalization, impeding proper treatment, and increasing treatment costs considerably. Although the incidence of...
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Experience of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in a Regional Hospital: 70 Cases in 7 Years

Lee J, Kim JW

BACKGROUND/AIMS: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions that frequently result in fatal outcomes. We investigated cases of SJS and TEN in a regional...
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A Clinical Observation of the Patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Jeju Island

Kim JW, Kim ST, Song DH

  • KMID: 2302884
  • Korean J Dermatol.
  • 2004 May;42(5):579-591.
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, acute life-threatening, hypersensitivity reaction usually to certain medications. Although SJS and TEN occur at an estimated incidence of 0.4...
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