- Tumor Necrosis Factor and Lymphotoxin-alpha Gene Polymorphism in Korean Children with Type 1 Diabetes
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Suh JS, Park SY, Jung MH, Suh BK, Kim TG, Lee BC
- KMID: 1629582
- Korean J Pediatr.
- 2005 Aug;48(8):871-876.
PURPOSE: Recently, it was reported that tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha) gene regions might be a susceptible loci to type 1 diabetes in Japanese. The purpose of this... -
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- Association Study of Single-Nucleotide Polymorphism in Lymphotoxin Alpha Gene and Bipolar I Disorder
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Kim SH, Jun TY
- KMID: 2029137
- Korean J Biol Psychiatry.
- 2012 Aug;19(3):134-139.
OBJECTIVES: Proinflammatory process has been implicated as an underlying mechanism of bipolar disorder and schizophrenia. Previous studies have suggested a possible role of lymphotoxin alpha (LTA) gene in the development... -
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- Lymphotoxin-alpah gene polymorphism in patients with glomerulonephritis
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Lee EY, Hong SY, Choi JS, Yang DH, Cho JT, Yoon SC
- KMID: 2143070
- Korean J Med.
- 2001 Jul;61(1):10-16.
BACKGROUND: Lymphotoxin (LT)-alpha is a cytokine that has been involved in the inflammatory response, the pathogenesis of autoimmune disease, and the development and progression of renal injury in various glomerulonephritis.... -
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- TNF-alpha and TNF-beta Polymorphisms are Associated with Susceptibility to Osteoarthritis in a Korean Population
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Han L, Song JH, Yoon JH, Park YG, Lee SW, Choi YJ, Nam SW, Lee JY, Park WS
- KMID: 1439771
- Korean J Pathol.
- 2012 Feb;46(1):30-37.
- doi: 10.4132/KoreanJPathol.2012.46.1.30
BACKGROUND: The tumor necrosis factor (TNF) is believed to play an important role in the pathophysiology of osteoarthritis (OA). Evidence shows that genetic polymorphisms make substantial contributions to the etiology... -
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- Identification of UVB Effects on Gene Expressed by Normal Human Melanocytes
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Kim HS, Park HH, Lee MH
- KMID: 1977852
- Korean J Dermatol.
- 2003 Dec;41(12):1597-1602.
BACKGROUND: Irradiation of the skin with ultraviolet rays result in alterations of immune response as well as melanogenesis and melanocarcinogenensis. These effects are largely mediated by soluble mediators released from... -
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- Activity of Cytokines and Expression of CD62L in Patients with Bronchial Asthma
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Song KS, Lee WY, Hong AR, Kim HS, Yong SJ, Shin KC
- KMID: 2114498
- Tuberc Respir Dis.
- 1998 Feb;45(1):90-98.
- doi: 10.4046/trd.1998.45.1.90
BACKGROUND: The CD4+ T-helper cells comprise functionally distinct subsets of Th1 and Th2 cells that are distinguished on the basis of differential cytokines production. Th1 cells secrete interferon-gamma, lymphotoxin, interleukin-2.... -
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- Gene Expression Profile Analysis by cDNA Array in the Subacromial Bursa of Patients with Rotator Cuff Disease
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Kim YS, Kim JM, Jung HW, Bigliani L, Blaine TA
- KMID: 2106436
- J Korean Orthop Assoc.
- 2008 Apr;43(2):171-180.
- doi: 10.4055/jkoa.2008.43.2.171
PURPOSE: To examine the expression pattern of inflammatory cytokines/receptors in the subacromial bursa of patients with rotator cuff disease using a cDNA(Complement DNA) Array technique. MATERIALS AND METHODS: Twenty two human... -
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- Association between the G252A Tumor Necrosis Factor-beta Gene Polymorphism and Medication-Overuse Headache
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Ishii M, Onaya T, Katoh H, Kiuchi Y, Kasai H, Kawamura M, Shimizu S
- KMID: 2287582
- J Clin Neurol.
- 2012 Dec;8(4):301-304.
- doi: 10.3988/jcn.2012.8.4.301
BACKGROUND AND PURPOSE: Migraine patients are particularly prone to the complication of medication-overuse headache (MOH). Although it has been shown that A allele carriers for the tumor necrosis factor (TNF)-beta... -
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- Histopathologic Study of the Intracranial Meningioma on the basis of Immunohistochemical Staining and Polymerase Chain Reaction
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Shin H, Lim SC, Lee SI
- KMID: 2010236
- J Korean Neurosurg Soc.
- 1996 Mar;25(3):562-574.
Meningioma is the most common primary intracranial neoplasm that originates from the meningothelial cells. It occurs mainly in adults, and has a female preponderance. It is classically classified into three... -
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- Silica induced Expression of IL-1beta, IL-6, TNF-beta, TGF-alpha, in the Experimental Murine Lung Fibrosis
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Ki SY, Park SW, Lee MR, Kim EY, Uh ST, Kim YH, Park CS, Lee HB
- KMID: 2050099
- Tuberc Respir Dis.
- 1998 Aug;45(4):835-845.
- doi: 10.4046/trd.1998.45.4.835
BACKGROUND: Silica-induced lung diseases is characterized by the accumulation of inflammatory cells at early stage and fibrosis in pulmonary parenchyma and interstitium at late stage. As a consequence of inflammation,... -
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- The Relationship between Polymorphisms in Tumor Necrosis Factor (TNF) Genes and Changes in Bone Mineral Density after Hormone Therapy in Postmenopausal Korean Women
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Chun S, Kim JG
- KMID: 2314092
- Osteoporosis.
- 2011 Apr;9(1):66-79.
OBJECTIVES: To determine the association between polymorphisms in tumor necrosis factor-alpha (TNF-alpha), and TNF-beta genes, and changes in bone mineral density (BMD) after hormone therapy (HT) in postmenopausal Korean women. MATERIALS... -
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- Gene Polymorphism of Tumor Necrosis Factor Beta in Major Depressive Disorder
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Jun T, Pae CU, Kim YH, Jang GH, Lee CT, Bahk WM, Kim KS
- KMID: 2340517
- J Korean Neuropsychiatr Assoc.
- 2000 Nov;39(6):1188-1195.
OBJECTIVE: Major depressive disorder is known to have high genetic predisposition and the main focus of recent genetic studies in major depressive disorder has been concentrated on association studies between... -
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- NcoI Restriction Fragment Length Polymorphism(RFLP) on the TNF-beta gene in Korean Patients with Type 1(insulin-dependent) Diabetes Mellitus
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Kim SK, Shin CS, Park KS, Kim SY, Lee HK, Min HK, O TG
- KMID: 2178009
- J Korean Diabetes Assoc.
- 1998 Jun;22(2):155-163.
BACKGROUND: To investigate whether a TNF-g gene polymorphism is associated with the development of insulin-dependent diabetes mellitus, we analyzed the TNF-g gene polymorphism with restriction enzyme Ncol in 38 Korean... -
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- Polymorphism of Tumor Necrosis Factor-beta Gene in Bipolar I disorder
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Jun TY, Lee KU, Pae CU, Kim W, Woo YS, Chae JH, Bahk WM
- KMID: 2341140
- J Korean Neuropsychiatr Assoc.
- 2005 Nov;44(6):671-675.
OBJECTIVES: Bipolar disorder is known to have a high genetic predisposition. Recently, the main focus of etiologic studies in bipolar disorder has been concentrated on molecular genetic approach including gene... -
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- The tumor necrosis factor beta * 1 allele is linked significantly to HLA-DR8 in Koreans with atrophic autoimmune thyroiditis who are positive for thyrotropin receptor blocking antibody
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Chung JH, Cho BY, Lee HK, Kim TG, Han H, Koh CS
- KMID: 1422171
- J Korean Med Sci.
- 1994 Apr;9(2):155-161.
- doi: 10.3346/jkms.1994.9.2.155
The localization and functional characteristics of tumor necrosis factor(TNF) beta gene raise the possibility that it may be involved in the susceptibility to autoimmune thyroid diseases. To investigate whether a... -
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- The Role of Tumor Necrosis Factor-alpha and Interleukin-1beta as Predictable Markers for Development of Adult Respiratory Distress Syndrome in Septic Syndrome
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Koh YS, Jang YH, Kim WS, Kim WD, Lee JD, Oh SH
- KMID: 2317875
- Tuberc Respir Dis.
- 1994 Oct;41(5):452-461.
BACKGROUND: Tumor necrosis factor(TNF)-alpha and Interleukin(IL)-1beta are thought to play a major role in the pathogenesis of the septic syndrome, which is frequently associated with adult respiratory distress syndrome(ARDS). In... -
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- Expression of Genetic Polymorphism of Interleukin-10 (IL-10) and Tumor Necrosis Factor-beta (TNF-beta) in Patients with Atopic Dermatitis
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Koh BK, Kim JS, Han H, Lee KH, Kim JW
- KMID: 2013630
- Korean J Dermatol.
- 2002 May;40(5):488-495.
BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disease. Atopic dermatitis is associated with increased IL-4, IL-5, IL-10 and IL-13 but decreased INF-gamma and TNF production. IL-10 production has... -
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- Comparison of the Efficacy of Topical Antihistamine/Mast Cell Stabilizers in vitro
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Kim SJ, Yoon TJ, Lee JE, Lee JS
- KMID: 2337815
- J Korean Ophthalmol Soc.
- 2010 Mar;51(3):406-417.
PURPOSE: To investigate the biologic effects of topical anti-allergic agents with H1-receptor antagonism and inhibition of histamine release from mast cells in the cultured conjunctival cells of patients with vernal... -
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- The Levels of Pro-Inflammatory Factors Are Significantly Decreased in Cerebral Palsy Patients Following an Allogeneic Umbilical Cord Blood Cell Transplant
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Bae SH, Lee HS, Kang MS, Strupp BJ, Chopp M, Moon J
- KMID: 1426155
- Int J Stem Cells.
- 2012 May;5(1):31-38.
BACKGROUND AND OBJECTIVES: The transplantation of human umbilical cord blood cells (hUCBCs) has been shown to attenuate the unregulated activation of microglia in a rat model of cerebral palsy (CP).... -
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- HLA, CTLA-4 and TNF-beta Gene Polymorphisms and Disease Susceptibility in Korean Children with Graves' Disease
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Song MY, Jung MH, Lee JS, Kim TG, Yang SW, Lee BC
- KMID: 2200127
- J Korean Soc Endocrinol.
- 2003 Feb;18(1):32-44.
BACKGROUND: Graves' disease(GD) is an organ-specific autoimmune disorder that is inherited as a complex trait. At present three loci, namely the human leukocyte antigen(HLA), the cytotoxic T lymphocyte antigen-4(CTLA-4) and... -
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