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Immunological abnormalities in patient with IgA nephropathy

Ihm CG, Woo JT, Chang YW, Kwon OS, Kim MJ

T cell immunity and phagocytic activity were studied in the blood of patients with IgA nephropathy in order to clarify their roles in the pathogenesis of IgA nephropathy. The percentages...
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High CD99 expression in memory T and B cells in reactive lymph nodes

Park CK, Shin YK, Kim TJ, Park SH, Ahn GH

We investigated the expression of CD99 in 35 hyperplastic perigastric lymph nodes, which were resected for gastric carcinoma or chronic peptic ulcer. Essentially, all lymphocytes in lymph nodes expressed CD99,...
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Immune mechanisms of Theiler's virus-induced demyelination

Kim BS, Palna JP

  • KMID: 755038
  • Exp Mol Med.
  • 1999 Sep;31(3):115-121.
No abstract available.
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Immune Response and the Tumor Microenvironment: How They Communicate to Regulate Gastric Cancer

Lee K, Hwang H, Nam KT

  • KMID: 1774539
  • Gut Liver.
  • 2014 Mar;8(2):131-139.
Gastric cancer is the second most common cause of cancer-related death in the world. A growing body of evidence indicates that inflammation is closely associated with the initiation, progression, and...
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Effects of Anti-salivary Gland Antibodies on Circulating and Tissue Lymphocytes: An Animal Experimental Study

Chang DK, Rabin BS

In the present study, normal guinea pigs were used to investigate the possible pathogenic role of cell-mediated immunity in Sjogren's syndrome. The effects of anti-salivary gland antibodies on circulating lymphocytes,...
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A clinicopathologic study on three cases of constrictive bronchiolitis

Myong NH, Shin DH, Lee KY

We describe the characteristic clinical and pathologic findings of three cases of constrictive bronchiolitis. All three patients were middle-aged women with chronic respiratory illness characterized by chronic cough, dyspnea, mild...
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Intervention with costimulatory pathways as a therapeutic approach for graft-versus-host disease

Kwon B

Graft-versus-host disease (GVHD) is mediated by mature donor T cells contained in the hematopoietic stem cell graft. During the development of GVHD, signaling through a variety of costimulatory receptors plays...
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Immunohistochemical characterization of the cellular infiltrate in airway mucosa of toluene diisocyanate (TDI)-induced asthma: comparison with allergic asthma

Park HS, Hwang SC, Nahm DH, Yim HE

Toluene diisocyanate (TDI) is the most prevalent agent in occupational asthma (OA) in Korea. The immuno-pathologic mechanism for TDI-induced bronchoconstriction remains to be clarified. We studied the immunohistochemical finding of...
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Relation between lymphocyte subpopulations of peripheral blood and immune responses of modified live hog cholera virus vaccine in pigs treated with an ionized alkali mineral complex

Park BK, Park YH, Seo KS

  • KMID: 1103474
  • J Vet Sci.
  • 2000 Jun;1(1):49-52.
Thirty-nine healthy pigs (28-32 days old) were purchased from a commercial swine farm and housed at swine pens of the College. The animals were vaccinated intramuscularly (1 ml) with an...
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Cloning a new allele form of bovine TNF-alpha

Ahn J

  • KMID: 1103522
  • J Vet Sci.
  • 2001 Aug;2(2):139-141.
Although little is known on the function of gammadelta T lymphocytes, there is increasing evidence that gammadelta T lymphocytes are early responders and modulators of immune responses against pathogens and...
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In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1

La S, Kim E, Kwon B

  • KMID: 1056231
  • Exp Mol Med.
  • 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive...
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Activated natural killer cell-mediated immunity is required for the inhibition of tumor metastasis by dendritic cell vaccination

Kim A, Noh YW, Kim KD, Jang YS, Choe YK, Lim JS

  • KMID: 1123764
  • Exp Mol Med.
  • 2004 Oct;36(5):428-443.
Immunization with dendritic cells (DCs) pulsed with tumor antigen can activate tumor-specific cytotoxic T lymphocytes (CTL), which is responsible for tumor protection and regression. In this study, we examined whether...
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Intratumoral Administration of Secondary Lymphoid Chemokine and Unmethylated Cytosine-phosphorothioate-guanine Oligodeoxynucleotide Synergistically Inhibits Tumor Growth in Vivo

Oh SM, Oh K, Lee DS

Secondary lymphoid tissue chemokine (SLC), which is expressed in T cell zones of secondary lymphoid organs, including the spleen and lymph nodes, strongly recruits both T lymphocytes and mature dendritic...
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Experimental Murine Fascioliasis Derives Early Immune Suppression with Increased Levels of TGF-beta and IL-4

Chung JY, Bae YA, Yun DH, Yang HJ, Kong Y

  • KMID: 1792122
  • Korean J Parasitol.
  • 2012 Dec;50(4):301-308.
In fascioliasis, T-helper 2 (Th2) responses predominate, while little is known regarding early immune phenomenon. We herein analyzed early immunophenotype changes of BALB/c, C57BL/6, and C3H/He mice experimentally infected with...
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Cytokine secretion patterns of T cells responding to haptenized-human serum albumin in toluene diisocyanate (TDI)-induced asthma patients

Lee M, Park S, Park HS, Youn JK

Our understanding immune response mechanisms to chemical allergens has been limited. It was partly due to the nature of antigens, recognized by T cells, not being well characterized. In...
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Delayed activation-induced T lymphocytes death in aplastic anemia: related with abnormal Fas system

Kim SC, Min YH, Lee S, Chung SY, Yoo NC, Lee JW, Hahn JS, Ko YW

  • KMID: 759056
  • Korean J Intern Med.
  • 1998 Feb;13(1):41-46.
OBJECTIVES: To quantitate apoptosis and Fas antigen expression of T lymphocytes by activation in aplastic anemia (AA) and compare with that of normal controls and completely-recovered AA, and to investigate...
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Involvement of tumor necrosis factor receptor superfamily (TNFRSF) members in the pathogenesis of inflammatory diseases

Kwon B, Kim BS, Cho HR, Park JE, Kwon BS

  • KMID: 1088652
  • Exp Mol Med.
  • 2003 Feb;35(1):8-16.
Current therapies for autoimmune diseases are not cures but merely palliatives, aimed at reducing symptoms. For the most part, these treatments provide nonspecific suppression of the immune system and thus...
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Prevalence of EBV RNA in sinonasal and Waldeyer's ring lymphomas

Lee JH, Lee SS, Park JH, Kim YW, Yang MH

A high incidence of a T cell phenotype of sinonasal lymphomas in other Asian countries has been associated with a high incidence of Epstein Barr virus (EBV) infection. We analyzed...
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Comparative Quantitative Analysis of Cluster of Differentiation 45 Antigen Expression on Lymphocyte Subsets

Im M, Chae H, Kim T, Park HH, Lim J, Oh EJ, Kim Y, Park YJ, Han K

BACKGROUND: Since the recent introduction of radioimmunotherapy (RIT) using antibodies against cluster of differentiation (CD) 45 for the treatment of lymphoma, the clinical significance of the CD45 antigen has been...
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Antitumor immunity induced by tumor cells engineered to express a membrane-bound form of IL-2

Chang MR, Lee WH, Choi JW, Park SO, Paik SG, Kim YS

  • KMID: 1056237
  • Exp Mol Med.
  • 2005 Jun;37(3):240-249.
Transduction of cytokine gene into tumor cells is a promising method of tumor therapy, but the value is limited by accompanying side effects. To focus antitumor immune response to tumor...
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