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Positive Association of Human SHC3 Gene with Schizophrenia in a Northeast Chinese Han Population

Lv Y, Sun Y, Wang GY, Yin J, Li CJ, Luo YY, Luan ZL

Objective Schizophrenia is one of the most devastating neuropsychiatric disorders. Genetic epidemiological studies have confirmed that schizophrenia is a genetic disease. Genes promoting neurodevelopment may be potential candidates for schizophrenia....
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The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy

Lv Y, Li B, Han K, Xiao Y, Yu X, Ma Y, Jiao Z, Gao J

Neddylation is a post-translational protein modification process. MLN4924 is a newly discovered pharmaceutical neddylation inhibitor that suppresses cancer growth with several cancer types. In our study, we first investigated the...
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Research Progress on Leptotrombidium deliense

Lv Y, Guo XG, Jin DC

This article reviews Leptotrombidium deliense, including its discovery and nomenclature, morphological features and identification, life cycle, ecology, relationship with diseases, chromosomes and artificial cultivation. The first record of L. deliense...
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Relative Abundance of a Vector of Scrub Typhus, Leptotrombidium sialkotense, in Southern Yunnan Province, China

Lv Y, Guo XG, Jin DC, Song WY, Fan R, Zhao CF, Zhang ZW, Mao KY, Zou YJ, Yang ZH

The chigger mite Leptotrombidium sialkotense is one of the 6 main vectors of scrub typhus in China. Before present study, L. sialkotense was found in some parts of Hunan province,...
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Operation start time and long-term outcome of hepatocellular carcinoma after curative hepatic resection

Lu Q, Li QS, Zhang W, Liu K, Li T, Yu JW, Lv Y, Zhang XF

Purpose: The objective of the current study was to examine the potential effects of surgery start times (morning vs. afternoon) on the long-term prognosis of patients after hepatic resection (HR)...
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Positive Association of TEAD1 With Schizophrenia in a Northeast Chinese Han Population

Sun Y, Wen L, Luo YY, Hu WJ, Ren HW, Lv Y, Zhang C, Gao P, Xuan LN, Wang GY, Li CJ, Xiang ZX, Luan ZL

Objective Schizophrenia is a complex and devastating psychiatric disorder with a strong genetic background. However, much uncertainty still exists about the role of genetic susceptibility in the pathophysiology of schizophrenia....
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Porcine circovirus type 2 increases interleukin-1beta and interleukin-10 production via the MyD88–NF-kappa B signaling pathway in porcine alveolar macrophages in vitro

Han J, Zhang S, Zhang Y, Chen M, Lv Y

Porcine alveolar macrophages (PAMs) represent the first line of defense in the porcine lung after infection with porcine circovirus type 2 (PCV2) via the respiratory tract. However, PCV2 infection impairs...
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Molecular and phylogenetic analysis of Anaplasma spp. in sheep and goats from six provinces of China

Zhang Y, Lv Y, Zhang F, Zhang W, Wang J, Cui Y, Wang R, Jian F, Zhang L, Ning C

Members of the genus Anaplasma are important emerging tick-borne pathogens in both humans and animals in tropical and subtropical areas. Here, we investigated the presence of Anaplasma spp. in 621...
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Expression of RUNX2/LAPTM5 in the Induction of MC3T3-e1 Mineralization and Its Possible Relationship with Autophagy

Xing L, Li Y, Li W, Liu R, Geng Y, Ma W, Qiao Y, Li J, Lv Y, Fang Y, Xu P

BACKGROUND: The study aims to correlate osteogenesis with autophagy during the mineralization induction of MC3T3-e1 through exploring the expression of runt-related transcription factor 2 (RUNX2)/lysosomal-associated transmembrane protein 5 (LAMPT5). METHODS: The...
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Cathepsin D deficiency delays central nervous system myelination by inhibiting proteolipid protein trafficking from late endosome/lysosome to plasma membrane

Guo DZ, Xiao L, Liu YJ, Shen C, Lou HF, Lv Y, Pan SY

This study aimed to investigate the role of cathepsin D (CathD) in central nervous system (CNS) myelination and its possible mechanism. By using CathD knockout mice in conjunction with immunohistochemistry,...
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