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Inflammation and Hepatic Fibrosis, Then Hepatocellular Carcinoma

Kwon OS, Choi SH, Kim JH

Inflammation is one of the most prominent characteristic features of chronic liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Most of HCC cases develop in patients with cirrhosis and...
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Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Augments Acute Lung Injury via Its Neutrophil Priming Effects

Choi JC, Jung JW, Kwak HW, Song JH, Jeon EJ, Shin JW, Park IW, Choi BW, Kim JY

Granulocyte macrophage-colony stimulating factor (GM-CSF) has immuno-stimulatory effects. We hypothesized that GM-CSF plays an important role both in lipopolysaccharide (LPS)- and hemorrhage-induced acute lung injury (ALI). We also postulated that...
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Human beta-defensin 2 is induced by interleukin-1b in the cornealepithelial cells

Shin JS, Kim CW, Kwon YS, Kim JC

  • KMID: 1097101
  • Exp Mol Med.
  • 2004 Jun;36(3):204-210.
Mammalian epithelia produce the various antimicrobial peptides against the bacterial or viral infection, thereby acting as the active immune modulators in the innate immunity. In this study, we examined the...
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