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Effectiveness of three different luteinizing hormone-releasing hormone agonists in the chemical castration of patients with prostate cancer: Goserelin versus triptorelin versus leuprolide

Shim M, Bang WJ, Oh CY, Lee YS, Cho JS

PURPOSE: To investigate the changes in testosterone levels and rates of chemical castration following androgen-deprivation therapy (ADT) with goserelin, triptorelin, and leuprolide. MATERIALS AND METHODS: We retrospectively reviewed the medical records...
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Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report

Lee M, Kim TH, Kim SJ, Jee BC

Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy. We report a case of PRES after 2 doses of depot...
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Therapeutic Effects of Leuprorelin (Leuprolide Acetate) in Sexual Offenders with Paraphilia

Choi JH, Lee JW, Lee JK, Jang S, Yoo M, Lee DB, Hong JW, Noh IS, Lim MH

BACKGROUND: This study examined the clinical effects of leuprolide acetate in sexual offenders with paraphilic disorders evaluated by means of objective psychiatric assessment. METHODS: The subjects of this study were seven...
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Uterine fibroid shrinkage after short-term use of selective progesterone receptor modulator or gonadotropin-releasing hormone agonist

Lee MJ, Yun BS, Seong SJ, Kim ML, Jung YW, Kim MK, Bae HS, Kim DH, Hwang JY

OBJECTIVE: The aim of this study was to evaluate the effect of short-term use of selective progesterone receptor modulator (SPRM) or gonadotropin-releasing hormone (GnRH) agonist on uterine fibroid shrinkage among...
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A Case of Foreign Body Granuloma Caused by Subcutaneous Injection of Leuprorelin Acetate

Moon KR, Lim HS, Lee JB, Kim SJ, Lee SC, Won YH, Yun SJ

  • KMID: 2353435
  • Korean J Dermatol.
  • 2016 Sep;54(8):634-637.
Leuprorelin acetate is a synthetic analog of luteinizing hormone-releasing hormone (LHRH). Recently, hormone-dependent tumors (prostate cancer and breast cancer) have been treated without surgery using this LHRH agonist. A 74-year-old...
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Leuprolide Acetate-induced Foreign Body Granuloma in a Patient with Prostate Cancer

Park SM, Kim JM, Kim GW, Mun JH, Song M, Kim HS, Kim BS, Kim MB, Ko HC

  • KMID: 2344381
  • Korean J Dermatol.
  • 2016 Jul;54(6):477-480.
Leuprolide acetate is an established luteinizing hormone-releasing hormone (LHRH) agonist used as a first-line treatment in advanced prostate cancer. An 80-year-old man presented with a localized erythematous patch with an...
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Good Response of a Salivary Duct Carcinoma to Androgen Deprivation Therapy

Lee JM, Lee JA, Lim SY, Kim SM, Lee YH, Yoon JG, Kang EJ

Salivary duct carcinoma (SDC) is a rare, aggressive tumor. Androgen deprivation therapy (ADT) has been shown to have beneficial effects on SDC-expressing androgen receptors (ARs). A 69-year-old male with a...
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Raloxifene Administration in Women Treated with Long Term Gonadotropin-releasing Hormone Agonist for Severe Endometriosis: Effects on Bone Mineral Density

Cho YH, Um MJ, Kim SJ, Kim SA, Jung H

OBJECTIVES: To evaluate the efficacy of raloxifene in preventing bone loss associated with long term gonadotropin-releasing hormone agonist (GnRH-a) administration. METHODS: Twenty-two premenopausal women with severe endometriosis were treated with leuprolide...
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Protective Effects of KH-204 in the Bladder of Androgen-Deprived Rats

Bae WJ, Ha US, Choi JB, Kim KS, Kim SJ, Cho HJ, Hong SH, Lee JY, Wang Z, Hwang SY, Kim SW

PURPOSE: We investigated the protective effects of the herbal formulation KH-204 in the bladder of androgen-deprived rats. MATERIALS AND METHODS: Male rats aged eight weeks were randomly divided into four groups,...
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Comments to "A Case of Pityriasis Rosea Associated with Leuprolide Acetate"

Yoon TY

  • KMID: 2132681
  • Korean J Dermatol.
  • 2015 Dec;53(10):818-819.
No abstract available.
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Significant adverse reactions to long-acting gonadotropin-releasing hormone agonists for the treatment of central precocious puberty and early onset puberty

Lee JW, Kim HJ, Choe YM, Kang HS, Kim SK, Jun YH, Lee JE

PURPOSE: Long-acting gonadotropin-releasing hormone agonists (GnRHa) are commonly used to treat central precocious puberty (CPP) in Korea. Although rare, there have been reports on the characteristic of adverse reactions of...
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A Case of Mental Retardation with Paraphilia Treated with Depot Leuprorelin

Park WS, Kim KM, Jung YW, Lim MH

Paraphilia is a psychiatric disease that has been difficult to cure. However, recently developed therapeutic methods hold promise. The patient was a 20-yr-old male with chief complaints of continuous masturbation,...
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Foreign Body Granuloma Secondary to Leuprorelin Acetate

Lee BI, Lee JY, Kim HO, Park YM

No abstract available.
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Is High-Dose Leuprorelin Acetate Effective and Safe in Asian Men with Prostate Cancer? An Open-Label, Non-Comparative, Multi-Center Clinical Trial

Lee SH, Lee HM, Kim SW, Lee ES, Hong SJ, Kim CS, Kang TW, Chung BH

  • KMID: 2386456
  • Yonsei Med J.
  • 2014 Mar;55(2):310-315.
PURPOSE: Leuprorelin is a well known luteinizing hormone releasing hormone agonist. However, there are insufficient data on the efficacy and safety of high dose leuprorelin acetate, especially in Asian patients...
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A Case of Pityriasis Rosea Associated with Leuprolide Acetate

Kim SR, Kim CY

  • KMID: 2301541
  • Korean J Dermatol.
  • 2014 Dec;52(12):917-918.
No abstract available.
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GnRH Agonist Co-treatment for Prevention of Primary Ovarian Insufficiency in Patients with Hematologic Malignancies Undergoing Chemotherapy

Chun S, Ji YI, Joo YD

  • KMID: 2321321
  • J Korean Soc Menopause.
  • 2013 Aug;19(2):93-100.
OBJECTIVES: The aim of this study was to assess the effect of gonadotropin-releasing hormone (GnRH) agonist co-treatment for gonadal protection in patients with hematologic neoplasms undergoing chemotherapy. METHODS: Young premenopausal women...
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Preliminary Study of Effect of Leuprolide Acetate Treatment on Sexual Fantasy of Sex Offenders

Ahn J, Shim G, Lee J, Lee J, Lee T, Roh I

This study investigated the effect of leuprolide acetate treatment on sex offenders' sexual fantasies and behaviors, as well as on their criminogenic psychological character and the risk of second conviction....
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Multicenter clinical trial of leuprolide acetate depot (Luphere depot 3.75 mg) for efficacy and safety in girls with central precocious puberty

Kim YJ, Lee HS, Lee YJ, Lim JS, Kim SY, Kim EY, Jin DK, Hwang IT, Hwang JS

PURPOSE: We evaluated the efficacy, safety and psychological aspect of monthly administrations of the gonadotropin-releasing hormone agonists (GnRHa), leuprolide acetate depot (Luphere depot 3.75 mg), in patients with precocious puberty. METHODS:...
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Sterile Abscess Formation Associated with Two Different Forms of Gonadotropin-Releasing Hormone Agonist in Central Precocious Puberty

Kim JM, Shin YL

Long-acting formulations of gonadotropin-releasing hormone (GnRH) agonists are indicated for treating central precocious puberty. Leuprolide acetate and triptorelin acetate are widely used in Korea. Local reactions related to GnRH agonists,...
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Effect of GnRH Analogs Leuprolide-Acetate and Triptorelin on Bone Mineral Density in Girls with Central Precocious Puberty

Bauer S, Nam HK, Rhie YJ, Park SH, Lee KH

  • KMID: 2384068
  • J Korean Soc Pediatr Endocrinol.
  • 2011 Aug;16(2):106-111.
PURPOSE: The objective of this study was to evaluate the effect of gonadotropin releasing hormone analog (GnRHa) treatment on bone mineral density (BMD) in girls with central precocious puberty (CPP)....
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