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Isolation of the Legionella Species from Specimens of Cooling Tower Water

Chung JH, Kang PS, Kim SB, Sakong J

The principal mode of the transmission of Legionnaires disease is an inhalation of the cooling tower water droplets in which Legionellae exist. As a central cooling system is popularized in...
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2 Cases of Legionnaires' Disease with Multiple Cavitary Mass-like Lesions in Patients with Systemic Lupuserythematosus

Jo SK, Shin JH, Jung KM, Kwon YJ, Kim MJ, Pyo HJ, Lee CK

  • KMID: 2307368
  • Korean J Nephrol.
  • 1998 Jan;17(1):157-161.
We report two cases of sporadic Legionnaires' disease in patients with systemic lupus erythematosus who had been receiving immunosuppressive agents. Their chest radiologic findings were characterized by rapidly progressive, multiple...
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Clinical Relevance of Positive NOW(TM) Legionella Urinary Antigen Test in a Tertiary-Care Hospital in Korea

Kim S, Sung H, Kim DJ, Kim MN

BACKGROUND: The morbidity and mortality of Legionnaires' disease are not established in Korea, because patients with community-acquired pneumonia (CAP) have rarely been investigated for Legionella. An assay for Legionella antigen...
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A Case of Community-acquired Legionnaires' Disease in a Renal Transplant Recipient

Seog W, Jung YJ, Park HW, Lee HK, Park MS, Park MY, Park KS, Oh MD, Ahn C, Kim EC, Choe KW

  • KMID: 2147946
  • Korean J Infect Dis.
  • 1999 Aug;31(4):353-357.
Legionella species are causative agents of both community-acquired and nosocomial pneumonia. The spectrum of disease ranges from asymptomatic infection to serious disease and two specific syndromes are identified, i.e., Legionnaires'...
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A Case of Fatal Nosocomial Legionnaires' Disease by Legionella pneumophila Serogroup 1

Kim KB, Kang MS, Chung HJ, Woo HJ, Kim MJ, You SH, Park SC

  • KMID: 1557278
  • Korean J Infect Dis.
  • 1998 Feb;30(1):106-110.
Nosocomial Legionnaires' disease has often been documented to occur in immunocompromised patients and to be severe, potentially fatal, pneumonia. We report a case of fatal nosocomial Legionnaires' disease developed shortly...
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Epidemiology of Legionella and Climatic Variables in Seoul, Korea

Park SH, Jin YH, Ahn MJ, Han SH, Kim HS, Kim JS, Park JH, Hong CK, Park SY, Oh AR, Lee JH, Kim IY, Shin YS

Legionella species are abundant in the built environment and are increasingly recognized as a cause of Legionnaires' disease (LD). As the number of cases of Legionnaires' disease acquired by local...
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Discovery of Diagnostic Biomarkers for Legionnaires' Disease: Virulence Gene Expression Profiling of Legionella pneumophila serogroup 1 in A/J Mouse Model

Kim SM, Sim HS, Kim HS, Shim HK, Yoon YK, Kim JY, Park YS, Park DW, Sohn JW, Kim MJ

BACKGROUND: Legionella pneumophila is the causative agent of Legionnaires' disease, a severe form of pneumonia. After L. pneumophila is inhaled through contaminated aerosols, it is phagocytized by alveolar macrophages, multiplies...
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Community-acquired Legionnaires’ Disease in a Newly Constructed Apartment Building

Ryu S, Yang K, Chun BC

OBJECTIVES: Legionnaires' disease (LD) is a severe type of pneumonia caused by inhalation of aerosols contaminated with Legionella. On September 22, 2016, a single case of LD was reported from...
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Determination of Proper Condition for Detection of Legionella pneumophila by Polymerase Chain Reaction

Jung DW, Lee HC, Chay KO, Chung JK, Ha DR, Ryu PY

  • KMID: 1807455
  • Chonnam Med J.
  • 2000 Jun;36(2):139-147.
BACKGROUND: Legionella pneumophila is the causative agent of Legionnaires' disease, a severe pneumonia, and the nonpneumonic syndrome Pontiac fever. Isolation of L. pneumophila from the patient specimens and environment is...
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Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages

Shim HK, Kim JY, Kim MJ, Sim HS, Park DW, Sohn JW, Kim MJ

Legionella bacterium, an intracellular pathogen of mononuclear phagocytes, causes acute fatal pneumonia, especially in patients with impaired cellular immune responses. Until recently, however, the toll-like receptor (TLR) engagement of bacterial...
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The Etiological Role of Legionella Pneumophila in Patients with Community-Acquired Pneumonia in Korea

Song HS, Suh JH, Ahn JH, Yoon BI, Lee SJ, Lee MG, Jun MJ, Kang MJ, Lee JM, Kim DG, Son JW, Park MJ, Hyun IG, Jung KS

BACKGROUND: Legionella pneumophila has been recognized as an important cause of community-acquired pneumonia(CAP) requiring hospitalization. However, epidemiological data on the occurrence of legionella-related pneumonia is unavailable in Korea. The purpose...
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Molecular Characterization of Legionellosis Drug Target Candidate Enzyme Phosphoglucosamine Mutase from Legionella pneumophila (strain Paris): An In Silico Approach

Hasan A, Mazumder H, Khan A, Hossain MU, Chowdhury

The harshness of legionellosis differs from mild Pontiac fever to potentially fatal Legionnaire's disease. The increasing development of drug resistance against legionellosis has led to explore new novel drug targets....
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Comparison of Sputum and Nasopharyngeal Swab Specimens for Molecular Diagnosis of Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila

Cho MC, Kim H, An D, Lee M, Noh SA, Kim MN, Chong YP, Woo JH

BACKGROUND: Differentiation of atypical pathogens is important for community-acquired pneumonia (CAP). In this study, we compared sputum and nasopharyngeal swabs (NPS) for use in detection of Mycoplasma pneumoniae (MP), Chlamydophila...
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