- The Efficacy of Lamivudine in Korean Patients with Chronic Hepatitis B
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Choi JY
- KMID: 760576
- Korean J Hepatol.
- 2005 Mar;11(1):25-30.
No abstract available. -
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- Treatment of Hepatitis B Virus Resistant to Lamivudine and Adefovir
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Kim JW
- KMID: 1767700
- Korean J Gastroenterol.
- 2009 May;53(5):329-330.
- doi: 10.4166/kjg.2009.53.5.329
No abstract available. -
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- A case report of treatment with pegylated interferon alpha for lamivudine-resistant chronic hepatitis B virus infection
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Hur WH, Woo HY, Jeong SW, You CR, Bae SH, Choi JY, Yoon SK
- KMID: 1073303
- Korean J Hepatol.
- 2008 Dec;14(4):513-518.
- doi: 10.3350/kjhep.2008.14.4.513
The wide use of lamivudine in chronic hepatitis B has produced a monotonic increase in patients with lamivudine resistance. Therefore, treating lamivudine resistance in chronic hepatitis B is a major... -
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- Development of Clevudine Resistance after Switching from Lamivudine in a Patient with Chronic Hepatitis B
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Koh KH, Kang CJ, Kim DH, Choi YW, Kim MJ, Cheong JY, Cho SW
- KMID: 783106
- Korean J Gastroenterol.
- 2008 Nov;52(5):325-328.
Clevudine is a nucleoside analog of the unnatural beta-L configuration which has potent antiviral activity against hepatitis B virus (HBV). Clevudine is expected to have similar pattern of resistance profile... -
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- Efficacy of Lamivudine Re-treatment and Relapse Patterns after Initial Lamivudine Treatment for Chronic Hepatitis B Infection
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Park JH, Park NH, Shin JW, Bang SJ, Kim DH, Joo KR, Kim DH
- KMID: 863154
- Korean J Hepatol.
- 2003 Sep;9(3):188-197.
BACKGROUND/AIMS: The post-treatment relapse patterns and efficacy of lamivudine re-treatment for relapsed patients have not been clarified. The aims of this study were to evaluate the relapse patterns after discontinuing... -
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- Predictive Factors and Efficacy of Lamivudine Treatment in Chronic Hepatitis B Infection
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Park NH, Shin JW, Park JH, Bang SJ, Kim DH, Joo KR, Kim DH
- KMID: 772561
- Korean J Gastroenterol.
- 2003 Oct;42(4):303-312.
BACKGROUND/AIMS: Lamivudine, an oral nucleoside analogue, effectively suppresses hepatitis B virus (HBV) replications and improves liver enzymes as well as liver histology. The aim of this study was to evaluate... -
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- Predictive Factors and Clinical Outcome of Viral Breakthrough during Lamivudine Treatment for Chronic Hepatitis B Infection
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Park NH, Shin JW, Park JH, Bang SJ, Kim DH, Joo KR, Kim DH
- KMID: 1085302
- Korean J Hepatol.
- 2003 Dec;9(4):293-303.
BACKGROUND/AIMS: Long-term treatment with lamivudine causes breakthrough, but the clinical course after lamivudine breakthrough is not well known. The aims of this study were to evaluate the clinical course... -
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- Pretreatment ALT Level and Histologic Activity as Predictors of HBeAg Loss in Lamivudine Treatment for Chronic Hepatitis B
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Kweon YO, Kang KH
- KMID: 760529
- Korean J Hepatol.
- 2004 Mar;10(1):31-41.
BACKGROUND/AIMS: Lamivudine is a potent inhibitor of hepatitis B virus replication, but an increased incidence of YMDD mutation may be associated with its long term use. Thus, the decision... -
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- Therapeutic Efficacy of Lamivudine in Patients With Hepatitis B Virus-Related Decompensated Cirrhosis in Korea
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Jung S, Suh DJ, Park HJ, Park YH, Song HG, Lee HC, Chung YH, Lee YS
- KMID: 863117
- Korean J Hepatol.
- 2002 Dec;8(4):418-427.
BACKGROUND/AIMS: Although several clinical trials have suggested that lamivudine treatment can be very effective in patients with decompensated HBV-associated cirrhosis, its role and clinical efficacy are still uncertain because... -
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- Adequacy of Immediate Lamivudine Trial for Chronic Hepatitis B Patients with Acute Exacerbation
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Lee CK, Suh JH, Cho YS, Won SY, Park IS
- KMID: 760528
- Korean J Hepatol.
- 2004 Mar;10(1):22-30.
BACKGROUND/AIMS: It has been unclear whether immediate antiviral therapy or observation under the expectation of spontaneous inactivation of hepatitis B virus (HBV), is more appropriate for the treatment of... -
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- Clinical and Virologic Characteristics of Lamivudine Resistance in HBV-associated Chronic Liver Disease
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Kim SS, Chung MG, Ju KT, Park DK, Kwon OS, Koo YS, Kim YK, Choi DJ, Hwang YJ, Kim JH
- KMID: 863116
- Korean J Hepatol.
- 2002 Dec;8(4):405-417.
BACKGROUND/AIMS: Lamivudine therapy in chronic hepatitis B has been shown to be effective in inhibiting HBV replication. However, lamivudine resistance has been developed with prolonged use. We studied to... -
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- Comparison of lamivudine-induced HBsAg loss rate according to age in children with chronic hepatitis B
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Kim JM, Choe BH, Chu MA, Cho SM
- KMID: 1381438
- Korean J Hepatol.
- 2009 Jun;15(2):168-178.
- doi: 10.3350/kjhep.2009.15.2.168
BACKGROUND/AIMS: The aim of this study was to establish the characteristics of children with hepatitis B e antigens (HBeAg) positive chronic hepatitis B who were cleared of hepatitis B surface... -
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- Efficacy and Safety of Adefovir Dipivoxil in Patients with Decompensated Liver Cirrhosis with Lamivudine Resistance Compared to Patients with Compensated Liver Disease
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Moon W, Choi MS, Moon YM, Paik SW, Lee JH, Koh KC, Yoo BC, Rhee JC, Shim SG
- KMID: 760590
- Korean J Hepatol.
- 2005 Jun;11(2):125-134.
BACKGROUND/AIMS: Adefovir dipivoxil is effective in patients with lamivudine-resistant hepatitis B virus (HBV). However, little is known about its role in Korean patients with decompensated liver cirrhosis. We retrospectively... -
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- Efficacy of Lamivudine in Patients with Hepatitis B e Antigen-Negative Chronic Liver Diseases
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Jeong ID, Park NH, Kim BC, Park JH, Seo KW, Kim DH, Joo KR, Kim DH
- KMID: 863140
- Korean J Hepatol.
- 2003 Jun;9(2):69-78.
BACKGROUND/AIMS: Lamivudine therapy is effective in inhibiting HBV replications in patients with HBeAg-negative chronic liver disease. However, the sustained response rate appears to be particularly poor, because the vast... -
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- Lamivudine versus Entecavir for Newly Diagnosed Hepatitis B Virus-Related Hepatocellular Carcinoma
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Kim JH, Sinn DH, Kim K, Kim H, Gwak GY, Paik YH, Choi MS, Lee JH, Koh KC, Paik SW
- KMID: 2412100
- Gut Liver.
- 2016 Nov;10(6):939-947.
- doi: 10.5009/gnl15527
BACKGROUND/AIMS: Antiviral therapy is a key component in the management of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients. However, whether the potent drug entecavir is more effective than a... -
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- Correlation of HBV DNA Level and Viral Breakthrough During Lamivudine Therapy for Chronic Hepatitis B
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Park HS, Lee DH, Heo J, Kim GH, Kang DH, Song GA, Cho M
- KMID: 760644
- Korean J Hepatol.
- 2006 Jun;12(2):173-183.
BACKGROUND/AIMS: Lamivudine is an effective therapy in chronic hepatitis B patients, but the emergence of resistant hepatitis B virus (HBV) mutants is a major concern. This study was performed... -
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- Hepatitis B surface antigen levels at 6 months after treatment can predict the efficacy of lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B
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Kim JH, Moon HW, Ko SY, Choe WH, Kwon SY
- KMID: 2069764
- Clin Mol Hepatol.
- 2014 Sep;20(3):274-282.
- doi: 10.3350/cmh.2014.20.3.274
BACKGROUND/AIMS: Quantitation of hepatitis B surface antigen (HBsAg) is an increasingly popular method to determine the treatment response in chronic hepatitis B (CHB) patients. The clinical value of HBsAg level... -
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- Factors affecting initial virologic response and emergence of resistant mutants after adefovir treatment in lamivudine-resistant chronic hepatitis B patients
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Cho JH, Cheong JY, Kang JK, Park JS, Lee MH, Lim NK, Hong SP, Kim SO, Yoo WD, Cho SW
- KMID: 1073330
- Korean J Hepatol.
- 2008 Mar;14(1):58-66.
- doi: 10.3350/kjhep.2008.14.1.58
BACKGROUND/AIMS: Adefovir dipivoxil (adefovir) effectively inhibits both wild-type and lamivudine-resistant hepatitis B virus (HBV) replication. The development of adefovir resistance is both delayed and infrequent compared with lamivudine resistance.... -
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- Lamivudine Therapy for Korean Children with Chronic Hepatitis B
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Koh H, Baek SY, Chung KS
- KMID: 1786205
- Yonsei Med J.
- 2007 Dec;48(6):927-933.
- doi: 10.3349/ymj.2007.48.6.927
PURPOSE: Lamivudine is known to be very effective in suppressing hepatitis B virus replication and virus induced necroinflammation. The aim of this study was to evaluate lamivudine therapy efficacy,... -
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- Detection of YMDD Motif Mutants by Oligonucleotide Chips in Lamivudine-Untreated Patients with Chronic Hepatitis B Virus Infection
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Heo J, Cho M, Kim HH, Shin YM, Jang HJ, Park HK, Kim CM, Kim GH, Kang DH, Song GA, Yang US
- KMID: 2157683
- J Korean Med Sci.
- 2004 Aug;19(4):541-546.
- doi: 10.3346/jkms.2004.19.4.541
Lamivudine, a nucleoside analogue, has been used widely as an effective antiviral agent for the treatment of patients with chronic hepatitis B virus (HBV) infection. However, the YMDD motif mutation... -
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