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A Case of Lymphoplasmacytic Lymphoma/Waldenström's Macroglobulinemia with IgM-κ and IgA-λ Biclonal Gammopathy

Shin WY, Bang HI, Kim J, Park R, Shin JW, Choi TY

  • Lab Med Online.
  • 2019 Oct;9(4):263-268.
  • doi: 10.3343/lmo.2019.9.4.263
Lymphoplasmacytic lymphoma (LPL) is a low-grade B-cell neoplasm, composed of small B lymphocytes, plasmacytoid lymphocytes, and plasma cells, usually involving bone marrow and sometimes lymph nodes or spleen. LPL with...
Acute Monoblastic Leukemia with t(11;17)(q23;q21): Fusion of the KMT2A(MLL) and MLLT6(AF17) Genes

Park CG, Mun SH, Lee AJ, Jeon CH, Suh HS, Kim SG

  • Lab Med Online.
  • 2019 Oct;9(4):258-262.
  • doi: 10.3343/lmo.2019.9.4.258
The KMT2A (formerly MLL) gene is associated with at least 10% of all cases of acute leukemia. More than 80 translocation partner genes of KMT2A have been discovered to date,...
A Case of Anti-Le(bH) Antibody Identified in a Patient with Ulcerative Colitis

Hong J, Kim MS, Kim JS, Park H, Ko DH, Hwang SH, Oh HB

  • Lab Med Online.
  • 2019 Oct;9(4):254-257.
  • doi: 10.3343/lmo.2019.9.4.254
A 67-year-old man previously diagnosed with ulcerative colitis complained of difficulty in defecation and underwent balloon dilatation of rectum, but the procedure failed. The patient was transferred to a surgical...
Therapeutic Plasma Exchange in a Patient with Hemophagocytic Lymphohistiocytosis

Roh J, Kim S, Nah H, Lee K, Kim HO

  • Lab Med Online.
  • 2019 Oct;9(4):249-253.
  • doi: 10.3343/lmo.2019.9.4.249
A 22-year old female patient with systemic lupus erythematosus presenting microangiopathic hemolytic anemia was treated with therapeutic plasma exchange 23 times. The patient's condition and laboratory findings (aspartate aminotransferase, alanine...
A Case of Chryseobacterium hominis Isolated from Human Blood Drawn Through Peripherally Inserted Central Catheter

Won D, Byun JH, Kim M, Yong D

  • Lab Med Online.
  • 2019 Oct;9(4):246-248.
  • doi: 10.3343/lmo.2019.9.4.246
Chryseobacterium hominis is non-fermenting Gram-negative rod that was first identified as a novel species in 2007. Here, we report the first clinical case of C. hominis bacteremia, which was confirmed...
Diagnostic Challenge: Primary Bone Marrow Diffuse Large B-cell Lymphoma Mimicking Systemic Autoimmune Diseases

Oh J, Kim Y, Lee ST, Lee KA

  • Lab Med Online.
  • 2019 Oct;9(4):242-245.
  • doi: 10.3343/lmo.2019.9.4.242
No abstract available.
Efficacy of Annexin A1 Immunostaining in Bone Marrow for the Diagnosis of Hairy Cell Leukemia

Park CH, Kim HY, Shin SY, Kim HJ, Jung CW, Kim JW, Kim SH

  • Lab Med Online.
  • 2019 Oct;9(4):236-241.
  • doi: 10.3343/lmo.2019.9.4.236
Splenic B-cell lymphomas (SBCLs) show characteristically pronounced splenomegaly without significant lymphadenopathy. Distinguishing hairy cell leukemia (HCL) from other SBCLs (splenic marginal zone lymphoma [SMZL], variant HCL [v-HCL], and splenic diffuse...
Iodine Deficiency in Neonates: Where Do We Stand After a Quarter Century of Initiating Iodization Programs?

Jafri L, Majid H, Ahmed S, Siddiqui I, Ghani F, Khan AH

  • Lab Med Online.
  • 2019 Oct;9(4):232-235.
  • doi: 10.3343/lmo.2019.9.4.232
An observational study was conducted at the Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, to assess the iodine status using the World Health Organization (WHO), United Nations...
Frequently Delayed Diagnosis and Misdiagnosis in MYH9-related Disorders: Data from Genetically Confirmed Cases of Korean Patients

Park CH, Kim YE, Lee KO, Kim SH, Oh KH, Kim I, Oh D, Kim HJ

  • Lab Med Online.
  • 2019 Oct;9(4):224-231.
  • doi: 10.3343/lmo.2019.9.4.224
MYH9-related disorders (MYH9RD) are autosomal-dominant disorders characterized by macrothrombocytopenia with or without leukocyte inclusion bodies or extra-hematological features, such as sensorineural deafness and renal impairment. MYH9RD can be misdiagnosed as...
Evaluation of the Automated Cross-Matching Instrument, ORTHO VISION, for Use in Blood Banks

Koo M, Lim J, Kim SY, Kim JM, Koo SH, Kwon GC

  • Lab Med Online.
  • 2019 Oct;9(4):218-223.
  • doi: 10.3343/lmo.2019.9.4.218
BACKGROUND: Automated systems are used widely for pre-transfusion tests in blood banks, in an attempt to reduce effort and human error. We evaluated the clinical performance of an automated blood...
Result Patterns and Characteristics of HBeAg and HBV DNA in Patients with Chronic Hepatitis B

Choi EJ, Kim JH, Han MS

  • Lab Med Online.
  • 2019 Oct;9(4):210-217.
  • doi: 10.3343/lmo.2019.9.4.210
BACKGROUND: Discrepancies in the results between hepatitis B e-antigen (HBeAg) and hepatitis B virus (HBV) DNA levels pose difficulties in the management of chronic hepatitis B (CHB). This study aims...
Distribution of adeG, adeB, adeE, adeY, abeM, and adeJ Efflux Pump Genes in Clinical Isolates of Acinetobacter Species from Korea

Choi IS, Choi JA, Jang SJ, Park G, Jeong SH, Kim CM, Lee OJ, Kang SH, Moon DS

  • Lab Med Online.
  • 2019 Oct;9(4):201-209.
  • doi: 10.3343/lmo.2019.9.4.201
BACKGROUND: The aim of the present study was to determine the frequency of six efflux pump genes in Acinetobacter clinical isolates collected from South Korean hospitals. METHODS: In this study, we...

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