- Interaction between thyroglobulin and ADAMTS16 in premature ovarian failure
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Pyun JA, Kim S, Kwack K
- KMID: 1805494
- Clin Exp Reprod Med.
- 2014 Sep;41(3):120-124.
- doi: 10.5653/cerm.2014.41.3.120
OBJECTIVE: The aim of the present study was to examine whether interactions between polymorphisms in the thyroglobulin and ADAM metallopeptidase with thrombospondin type 1 motif, 16 (ADAMTS16) genes are associated... -
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- Screening study for genetic polymorphisms affecting pharmacokinetics of simvastatin
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Im S, Kim BH, Lee K, Kwack K, Yim SV
- KMID: 2383599
- Transl Clin Pharmacol.
- 2016 Mar;24(1):43-54.
- doi: 10.12793/tcp.2016.24.1.43
Simvastatin reduces plasma cholesterol by inhibiting HMG-CoA reductase (HMGR) and is widely used in the treatment of hypercholesterolemia. To screening the possible genetic factors affecting the pharmacokinetics (PK) of simvastatin,... -
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- No Association between Single Nucleotide Polymorphisms in Urocanase Domain Containing 1 (UROC1) and Autism Spectrum Disorders (ASDs) in the Korean Population
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Park J, Ro M, Nam M, Bang HJ, Yang JW, Choi KS, Kim SK, Chung JH, Kwack K
- KMID: 2291656
- J Korean Acad Child Adolesc Psychiatry.
- 2012 Mar;23(1):8-13.
OBJECTIVES: Urocanase domain containing 1 (UROC1) has never been studied in prior studies on autism spectrum disorders (ASDs). UROC1 causes urocanic aciduria, one of the symptoms of which is mental... -
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- Erythropoietin-producing Human Hepatocellular Carcinoma Receptor B1 Polymorphisms are Associated with HBV-infected Chronic Liver Disease and Hepatocellular Carcinoma in a Korean Population
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Kim KY, Lee SK, Kim MH, Cheong JY, Cho SW, Yang KS, Kwack K
- KMID: 2166419
- Genomics Inform.
- 2008 Dec;6(4):192-201.
Erythropoietin-producing human hepatocellular carcinoma receptor B1 (EPHB1) is a member of the Eph family of receptor tyrosine kinases that mediate vascular system development. Eph receptor overexpression has been observed in... -
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- Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate
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Jin LH, Kim BH, Lee JH, Lee K, Kwack K, Yim SV
- KMID: 2406997
- Transl Clin Pharmacol.
- 2017 Dec;25(4):166-172.
- doi: 10.12793/tcp.2017.25.4.166
Talniflumate is a phthalidyl ester of niflumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis. To screen the... -
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- Polymorphisms in RAS Guanyl-releasing Protein 3 are Associated with Chronic Liver Disease and Hepatocellular Carcinoma in a Korean Population
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Oh AR, Lee SK, Kim MH, Cheong JY, Cho SW, Yang KS, Kwack K
- KMID: 2166418
- Genomics Inform.
- 2008 Dec;6(4):181-191.
RAS guanyl-releasing protein 3 (RasGRP3), a member of the Ras subfamily of GTPases, functions as a guanosine triphosphate (GTP)/guanosine diphosphate (GDP)-regulated switch that cycles between inactive GDP- and active GTP-bound... -
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- Screening study for genetic polymorphisms affecting pharmacokinetics of pioglitazone
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Yun JY, Kim BH, Lee JH, Lee K, Kwack K, Yim SV
- KMID: 2413842
- Transl Clin Pharmacol.
- 2016 Dec;24(4):194-202.
- doi: 10.12793/tcp.2016.24.4.194
Pioglitazone is known to have antidiabetic effects through decreasing peripheral, hepatic and vascular insulin resistance by the stimulation of PPAR gamma. To address the possible genetic factors affecting the pharmacokinetics... -
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- Efficient gene delivery in differentiated human embryonic stem cells
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Kim JH, Do HJ, Choi SJ, Cho HJ, Park KH, Yang HM, Lee SH, Kim DK, Kwack K, Oh SK, Moon SY, Cha KY, Chung HM
- KMID: 1033099
- Exp Mol Med.
- 2005 Feb;37(1):36-44.
Human embryonic stem (hES) cells are capable of differentiating into pluralistic cell types, however, spontaneous differentiation generally gives rise to a limited number of specific differentiated cell types and a... -
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- Sex-specific differences in the association of a common aldehyde dehydrogenase 2 gene polymorphism and alcohol consumption with stroke risk in a Korean population: a prospective cohort study
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Shin C, Kwack K, Cho NH, Kim SH, Baik I
- KMID: 2313813
- Nutr Res Pract.
- 2015 Feb;9(1):79-86.
- doi: 10.4162/nrp.2015.9.1.79
BACKGROUND/OBJECTIVES: It is well-known that alcohol consumption is associated with stroke risk as well as with aldehyde dehydrogenase 2 gene (ALDH2) polymorphisms. However, it is unclear whether ALDH2 polymorphisms are... -
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- Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study
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Pyun JA, Kim S, Park K, Baik I, Cho NH, Koh I, Lee JY, Cho YS, Kim YJ, Go MJ, Shim E, Kwack K, Shin C
- KMID: 2166490
- Genomics Inform.
- 2012 Jun;10(2):88-98.
- doi: 10.5808/GI.2012.10.2.88
Lipoprotein lipase (LPL) plays an essential role in the regulation of high-density lipoprotein cholesterol (HDLC) and triglyceride levels, which have been closely associated with cardiovascular diseases. Genetic studies in European... -
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