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Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain

Lee HG, Kim YO, Choi JI, Han XH, Shin YU, Yoon MH

Background: There is still unmet need in treating neuropathic pain and increasing awareness regarding the use of drug combinations to increase the effectiveness of treatment and reduce adverse effects in...
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Effective ketogenic diet in CACNA1A-related ‘epilepsy of infancy with migrating focal seizures’

Na H, Lee S, Kim YO

Genetic causes of developmental and epileptic encephalopathy (DEE) have been rapidly uncovered from mid-2010s. The mutations of gene enconding calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A) are recently...
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Alteration in Cngb1 Expression upon Maternal Immune Activation in a Mouse Model and Its Possible Association with Schizophrenia Susceptibility

Lee H, Kang SW, Jeong H, Kwon JT, Kim YO, Kim HJ

Objective: The cyclic nucleotide-gated channel (Cng) regulates synaptic efficacy in brain neurons by modulating Ca2+ levels in response to changes in cyclic nucleotide concentrations. This study investigated whether the expression...
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Cohen–Gibson syndrome in a family: The first familial case report

Kang YJ, Kim YO

Cohen–Gibson syndrome (CGS) was first reported by Cohen et al., who identified the mutation of the gene encoding the embryonic ectoderm development (EED) in a patient with phenotypes similar to...
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West syndrome with hyperkinesia and cortical visual impairment: A case report of GRIN1 encephalopathy

Choi SA, Kim YO

West syndrome (WS) presenting with infantile spasms, developmental delay, and hypsarrhythmia has genetic etiology in some patients. Movement disorders or visual impairment that share genetic underpinnings with infantile spasms can...
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A Rare Case of Pulmonary Arteriovenous Malformation Caused by Hereditary Hemorrhagic Telangiectasia in a Hemodialysis Patient

Bahk S, Bu SH, Kim HD, Won Y, Lee HG, Kim YO

Hereditary hemorrhagic telangiectasia (HHT) is an uncommon autosomal dominant disorder resulting in vascular malformation, such as pulmonary arteriovenous malformation (PAVM). Here, we report a rare case of pulmonary arteriovenous malformation...
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Combined hydrocortisone, ascorbic acid, and thiamine therapy for septic shock with complicated intraabdominal infection: before and after cohort study

Kim YO, Yoo KS, Yoon KW, Park HJ, Park CM

Purpose: The aim of this study was to assess the efficacy of intravenous hydrocortisone, ascorbic acid, and thiamine (HAT) combination therapy in complicated intraabdominal infection (cIAI) patients with septic shock. Methods:...
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A Case of Laryngeal Lymphoepithelial Carcinoma

Choi DG, Kim YO, Lee HS

Laryngeal lymphoepithelial carcinoma (LEC) is a rare tumor with only 34 cases in the published literature. Epidemiologically, laryngeal LEC is extremely rare in Asian. Originally, LEC is a common type...
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Mirror Movements in a Pediatric Patient with a Basal Ganglia Germinoma

Cheo H, Kim SK, Lee KH, Baek HJ, Kim YO

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Analysis for factors of brain death donor processing for face and hand transplantation in Korea: how much time will be available from brain death to transplantation?

Hong JW, Chung SW, Ahn SJ, Lee WJ, Lew DH, Kim YO

Background: Face and hand transplantation has naturally evolved from reconstruction and transplantation. However, few institutes or nations perform face transplantation. Difficulties in performing face transplantation limit approvals by the institution...
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Staged reconstruction of a chronically infected large skull defect using free tissue transfer and a patient-specific polyetheretherketone implant

Moon SJ, Jeon HB, Kim EH, Lew DH, Kim YO, Hong JW

Reconstructions of extensive composite scalp and cranial defects are challenging due to high incidence of postoperative infection and reconstruction failure. In such cases, cranial reconstruction and vascularized soft tissue coverage...
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Antinociceptive role of neurotensin receptor 1 in rats with chemotherapy-induced peripheral neuropathy

Yin M, Kim YO, Choi JI, Jeong S, Yang SH, Bae HB, Yoon MH

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect of anti-cancer drugs. Neurotensin receptors (NTSRs) are widely distributed within the pain circuits in the central nervous system. The purpose...
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Applicative Factors of Helmet Molding Therapy in Late-diagnosed Positional Plagiocephaly

Kim MJ, Kang MK, Deslivia MF, Kim YO, Choi JW

Background: Although the benefits of helmet therapy for positional plagiocephaly are strongly correlated with age, the effective period remains controversial. However, most physicians agree that effective results can be obtained...
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Association between Blood Pressure and Renal Progression in Korean Adults with Normal Renal Function

Lee KP, Kim YS, Yoon SA, Han K, Kim YO

Background: Although hypertension (HTN) is a well-established major risk factor for renal progression in patients with chronic kidney disease (CKD), few studies investigating its role in renal deterioration in the...
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Renal Artery Stenosis Presenting at Sudden Flash Pulmonary Edema in a Patient with Solitary Kidney

Choi J, Kim YO, Won Y, Na SJ

Flash pulmonary edema is characterized by a sudden episode of dyspnea resulting from acute pulmonary venous congestion, which resolves rapidly. We report a case of renal artery stenosis presenting as...
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Safety and feasibility of ultrasound-guided insertion of peripherally inserted central catheter performed by an intensive care trainee

Lee Y, Ryu JA, Kim YO, Gil E, Song YM

Background: We investigated the safety and feasibility of ultrasound-guided peripherally inserted central venous catheter (PICC) placements performed by intensive care medical trainees in comparison to PICC placements performed by intensivists. Methods:...
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Benign Convulsions with Mild Gastroenteritis

Kim YO

Benign convulsions with mild gastroenteritis (CwG) are a well-known type of benign seizures that occur in infants and children aged between 6 months and 3 years and are associated with...
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Periventricular nodular heterotopia in a child with a mild Mowat–Wilson phenotype caused by a novel missense mutation of ZEB2

Kim YO, Lee YY, Kim MK, Woo YJ

Periventricular nodular heterotopia (PNH) is a malformation of cortical development in which normal neurons inappropriately cluster in periventricular areas. Patients with Mowat–Wilson syndrome (MWS) typically present with facial gestalt, complex...
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Influence of clozapine on neurodevelopmental protein expression and behavioral patterns in animal model of psychiatric disorder induced by low-level of lead

Lee H, Lee M, Kim HK, Kim YO, Kwon JT, Kim HJ

Exposure to lead during pregnancy is a risk factor for the development of psychiatric disorders in the offspring. In this study, we investigated whether exposure to low levels of lead...
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Analysis of factors involved in brain-death donor processing for face transplantation in Korea: How much time is available from brain death to transplantation?

Hong JW, Chung SW, Ahn SJ, Lee WJ, Lew DH, Kim YO

BACKGROUND: Face transplantation has naturally evolved from reconstructive procedures. However, few institutions perform face transplantations, because it is time-consuming and it is necessary to justify non-vital organ transplantation. We investigated...
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