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Association of Sub-Threshold Amyloid Retention With Neuropsychological Performance in Cognitively Normal Older Adults Without the APOE ε4 Allele

Choi JW, Wang SM, Um YH, Na HR, Kim NY, Lim HK, Lee CU, Kang DW

Objective: Recent evidence shows that the quantitative value of amyloid-beta (Aβ) deposition below the threshold of Aβ positivi-ty carries biological and clinical significance regarding future cognitive decline. We evaluated whether...
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Standardization of the pathologic diagnosis of appendiceal mucinous neoplasms

Kang DW, Kim Bh, Kim JM, Kim J, Chang HJ, Chang MS, Sohn JH, Cho MY, Jin SY, Chang HK, Han HS, Kim JY, Kim HS, Park DY, Park HY, Lee SJ, Lee W, Lee HS, Kang YN, Choi Y, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

Although the understanding of appendiceal mucinous neoplasms (AMNs) and their relationship with disseminated peritoneal mucinous disease have advanced, the diagnosis, classification, and treatment of AMNs are still confusing for pathologists...
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Association between Dementia and Clinical Outcome after COVID-19: A Nationwide Cohort Study with Propensity Score Matched Control in South Korea

Wang SM, Park SH, Kim NY, Kang DW, Na HR, Um YH, Han S, Park SS, Lim HK

Objective Despite a high prevalence of dementia in older adults hospitalized with severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2), or so called COVID-19, research investigating association between preexisting diagnoses...
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Patent Foramen Ovale Closure in Old Stroke Patients: A Subgroup Analysis of the DEFENSE-PFO Trial

Kwon H, Lee PH, Song JK, Kwon SU, Kang DW, Kim JS

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Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control

Wang SM, Park SS, Park SH, Kim NY, Kang DW, Na HR, Bae YY, Lee JW, Han S, Lim HK

Objective: No previous study examined impact of dementia in the outcome of allogeneic hematopoietic stem cell transplantation (HSCT). We aimed to investigate overall survival (OS) of patients with dementia after...
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Development of Random Forest Algorithm Based Prediction Model of Alzheimer’s Disease Using Neurodegeneration Pattern

Kim J, Lee M, Lee MK, Wang SM, Kim NY, Kang DW, Um YH, Na HR, Woo YS, Lee CU, Bahk WM, Kim D, Lim HK

Objective Alzheimer’s disease (AD) is the most common type of dementia and the prevalence rapidly increased as the elderly population increased worldwide. In the contemporary model of AD, it is...
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Bee venom reduces burn-induced pain via the suppression of peripheral and central substance P expression in mice

Kang DW, Choi JG, Kim J, Park JB, Lee JH, Kim HW

Background: Scalding burn injuries can occur in everyday life but occur more frequently in young children. Therefore, it is important to develop more effective burn treatments. Objectives: This study examined the...
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Association of Alcohol Intake and Fracture Risk in Elderly Varied by Affected Bones: A Nationwide Longitudinal Study

Wang SM, Han KD, Kim NY, Um YH, Kang DW, Na HR, Lee CU, Lim HK

Objective Previous studies investigating association of alcohol intake and fracture risk in elderly yielded conflicting results. We first examined the association between alcohol intake and total fracture risk in elderly...
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Reliability and Clinical Utility of Machine Learning to Predict Stroke Prognosis: Comparison with Logistic Regression

Jang SK, Chang JY, Lee JS, Lee EJ, Kim YH, Han JH, Chang DI, Cho HJ, Cha JK, Yu KH, Jung JM, Ahn SH, Kim DE, Sohn SI, Lee JH, Park KP, Kwon SU, Kim JS, Kang DW, KOSNI Investigators

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Risk Factors Related to Poor Threshold, Discrimination, and Identification Scores in Patients with Chronic Rhinosinusitis with Olfactory Dysfunction

Kang DW, Min HK, Kwon OE, Kim SW, Min JY

Background and Objectives Although patients with chronic rhinosinusitis (CRS) present a similar degree of olfactory dysfunction, their impairments in threshold, discrimination, and identification test results may vary. We investigated factors...
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Differential Impact of Cigarette Smoking on Fracture Risks in Subjective Cognitive Decline and Dementia: A Nationwide Longitudinal Study

Um YH, Wang SM, Han Kd, Kim NY, Kang DW, Na HR, Lee CU, Lim HK

Objective We aimed to explore the differential impact of cigarette smoking on fracture risks in SCD and dementia. Methods A nationwide population-based cohort study design was used. Out of all the...
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IgG Seroprevalence of COVID-19 among Individuals without a History of the Coronavirus Disease Infection in Daegu, Korea

Song SK, Lee DH, Nam JH, Kim KT, Do JS, Kang DW, Kim SG, Cho MR

Background: Seroprevalence studies of coronavirus disease 2019 (COVID-19) from many countries have shown that the number of undiagnosed missing cases is much larger than that of confirmed cases, irrespective of...
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A Case of Ischemic Stroke in Young Patient Associated with Marijuana Use

Ha SY, Kang DW, Lee SH

A 21-year-old female patient complaining of hemiparesis was diagnosed with right middle cerebral artery infarction. No risk factor was found, despite an extensive young-age stroke work-up, except her history of...
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Effects of Moderate Intensity Exercise on the Cortical Thickness and Subcortical Volumes of Preclinical Alzheimer’s Disease Patients: A Pilot Study

Um YH, Wang SM, Kim NY, Kang DW, Na HR, Lee CU, Lim HK

Objective We aimed to explore the impact of moderate intensity exercise on the cortical thickness and subcortical volumes of preclinical Alzheimer’s disease (AD) patients. Methods Sixty-three preclinical AD patients with magnetic...
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Efficacies of Cognitive Interventions in the Elderly with Subjective Cognitive Decline: A Prospective, Three-Arm, Controlled Trial

Hong YJ, Lee JH, Choi EJ, Han N, Kim JE, Park SH, Kim HJ, Kang DW

Background and Purpose A cognitive intervention (CI) is thought to improve cognition and delay cognitive decline via neuronal plasticity and cognitive resilience. Subjective cognitive decline (SCD) might be the first symptomatic...
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Changes in High-Density Lipoprotein Cholesterol and Risks of Cardiovascular Events: A Post Hoc Analysis from the PICASSO Trial

Lee EJ, Kwon SU, Park JH, Kim YJ, Hong KS, Yu S, Hwang YH, Lee JS, Lee J, Rha JH, Heo SH, Ahn SH, Seo WK, Park JM, Lee JH, Kwon JH, Sohn SI, Jung JM, Kim HY, Kim EG, Kim SH, Cha JK, Park MS, Nam HS, Kang DW, on Behalf of PICASSO Investigators

Background and purpose Whether pharmacologically altered high-density lipoprotein cholesterol (HDL-C) affects the risk of cardiovascular events is unknown. Recently, we have reported the Prevention of Cardiovascular Events in Asian Patients...
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Standardized Pathology Report for Colorectal Cancer, 2nd Edition

Kim Bh, Kim JM, Kang GH, Chang HJ, Kang DW, Kim JH, Bae JM, Seo AN, Park HS, Kang YK, Lee KH, Cho MY, Do IG, Lee HS, Chang HK, Park DY, Kang HJ, Sohn JH, Chang MS, Jung ES, Jin SY, Yu E, Han HS, Kim YW, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of the ‘Standardized Pathology Report for Colorectal Cancer,’ which was developed by the Gastrointestinal Pathology Study Group (GIP) of the Korean Society of Pathologists, was published 13...
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Pancreatic High-Grade Neuroendocrine Neoplasms in the Korean Population: A Multicenter Study

Kim H, An S, Lee K, Ahn S, Park DY, Kim JH, Kang DW, Kim MJ, Chang MS, Jung ES, Kim JM, Choi YJ, Jin SY, Chang HK, Cho MY, Kang YK, Kang M, Ahn S, Kim YW, Hong SM, on behalf of the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

Purpose The most recent 2017 World Health Organization (WHO) classification of pancreatic neuroendocrine neoplasms (PanNENs) has refined the three-tiered 2010 scheme by separating grade 3 pancreatic neuroendocrine tumors (G3 PanNETs) from...
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Effects of Gamma-Glutamyl Transferase on Stroke Occurrence Mediated by Atrial Fibrillation

Yang W, Kang DW, Lee SH

BACKGROUND AND PURPOSE: Gamma-glutamyl transferase (GGT) is reported to be associated with stroke independently of the conventional risk factors. However, the underlying mechanism remains to be identified. This study focused...
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Treatment of intractable orofacial infection: Case reports

Kang DW, Yun PY, Kim YK

In severe cases, intractable infections in the orofacial area can lead to breathing difficulties due to closed airway, mediastinitis, and spread of infection along the blood vessels. Moreover, these conditions...
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