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Insular Carcinoma: An Aggressive Subtype of Differentiated Thyroid Neoplasms

Nam SJ, Lee SD, Oh YR, Yang JH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):229-234.
PURPOSE: Insular carcinoma is a rare subtype of thyroid cancer which is first described by Carcangiu in 1984. It is intermediate in aggressiveness between well differentiated and anaplastic thyroid carcinoma. But its origin,...
Efficacy of Local Radiotherapy as a Salvage Modality for Hepatocellular Carcinoma Which is Refractory to TACE ( Transcatheter Arterial Chemoembolization )

Park HC, Seong J, Lim JJ, Kim GE, Han KH, Chon CY, Moon YM, Lee DY, Lee JT, Suh CO

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):220-228.
PURPOSE: Transcatheter arterial chemoembolization (TACE) has been actively performed for the treatment of unresectable or inoperable hepatocellular carcinoma. However, for the patients with treatment failure after TACE, few options are available for salvage....
Accuraey of Cancer Death Certificates in KOREA: A comparison between diagnoses in the central cancer registry and certified underlying causes of death

Lee DH, Shin HR, Ahn DH, Chun BY, Kam S, Ahn YO

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):210-219.
PURPOSE: We evaluated the accuracy of death certificates for persons who registered in the Central Cancer Registry in 1993 and died from 1993 to 1995. MATERIALS AND METHODS: The study consisted...
Tumor - specific Virus Replication and Cytotoxicity of E1B 55 kD - deleted Adenovirus

Kim J, Lee B, Kim J, Ahn JB, Park JO, Yoo NC, Kim JH, Roh JK, Min JS, Kim BS, Lee H

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):200-209.
PURPOSE: To overcome the limitations of cancer gene therapy using replication-incom- petent adenovirus, we generated E1B 55 kD-deleted adenovirus (YKL-1) by polymerase chain reaction (PCR) and homologous recombination. We then investigated tumor-specific virus replication...
Construction of MAGE - 3 Expressing Plasmid for Development of DNA Vaccine Encoding MAGE - 3 Cancer Antigen

Park JW, Lee MH, Yoon SJ, Baek WK, Suh SI, Suh MH, Lee KD, Yu TH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):191-199.
PURPOSE: The spectrum of melanoma antigen gene (MAGE)-expressing tumor is very wide and the gene of MAGE express antigens that are targets for specific recognition by cytotoxic T lymphocytes derived from tumor-bearing patients....
A Clinical Study of Pediatric Myelodysplastic Syndrome: Application of International Prognostic Scoring System and the Review of the Korean Literature

Kook H, Kim CJ, Yoon WS, Ryu NE, Chung KJ, Hwang TJ

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):178-190.
PURPOSE: Myelodysplastic syndrome (MDS) in children needs to be elucidated in terms of clinical characteristics, natural history, the most effective treatment and prognostic factors, as the disease is very rare and its definition...
Results of Treatment with ProMACE - CytaBOM Regimen for Aggressive Non - Hodgkins Lymphoma

Eo WK

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):168-177.
PURPOSE: Despite intensive search for the optimal combination chemotherapy for aggres- sive non-Hodgkins lymphoma (NHL), the CHOP regimen is still the standard therapy. We investigated the clinical efficacy of ProMACE-CytaBOM, a third generation...
Radiation-induced Apoptotic Signaling Pathway in HL - 60 Cells

Ahn SJ, Park RK, Lee SR, Chung WK, Nah BS, Nam TK, Chung HT, Moon SR, Kang HK, Park SJ

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):156-167.
PURPOSE: The mechanical insights of death of cancer cells by ionizing radiation are not yet clearly defined. Recent evidences have demonstrated that radiation therapy may induce cell death via activation of signaling pathway...
Stereotactic Radiotherapy for the Treatment of Brain Metastases

Kim DY, Ahn YC, Huh SJ, Lee JI, Nam DH, Hong SC, Shin HJ, Park K, Kim JH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):148-155.
PURPOSE: To evaluate the clinical results of stereotactic radiosurgery (SRS) and frac- tionated stereotactic radiotherapy (FSRT) for metastatic brain tumors. MATERIALS AND METHODS: Nineteen patients with brain metastases (34 lesions) were treated with...
Expression of Prostatic Carcinoma Oncogene PTI - 1 in Prostatic Carcinoma , Prostatic Intraepithelial Neoplasia and Benign Prostatic Hyperplasia Using in situ PCR

Lee TJ, Park ES, Yoo JH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):136-147.
PURPOSE: Prostatic tumor induced gene-1 (PTI-1) is a mutated human EF-la and putative prostatic carcinoma tumor-inducing oncogene, that is differently expressed in prostatic cancer and benign prostatic hyperplasia. And, it is more sensitive...
Relationship of HPV Detection and p53 Expression in Urinary Bladder Cancer

Kee KH, Shin HM, Kim YC

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):129-135.
PURPOSE: The purpose of this study was to investigate the relationship between aberrant p53 expression and the presence of human papillomavirus DNA in transitional cell carcinomas of the urinary bladder. MATERIALS AND...
Chromosomal Aberrations in Ovarian Carcinoma Cell Line, SNU - S , Using Chromosome Painting

Kang JS, Kim DW, Chun YH, Park SH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):120-128.
PURPOSE: The characterization of all recognizable chromosomal rearrangements was dis- turbed by technical limitation of conventional cytogenetic methods. Recently, the strong usefullness of generation of chromosome specific painting probes in identification of marker...
Expressions of Cell Cycle Control Genes in Human Uterine Cervical Cancer Cells

Ahn JG, Lee TS, Cho JW, Baek WK, Suh SI, Suh MH, Park JW, Cha SD

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):110-119.
PURPOSE: Recently, many aspects of biological functions of cyclins, cyclin-dependent kinases (CDKs), CDK inhibitors and Rb gene have been reported, and the cell cycle control genes are considered to act important roles in...
Detection of Human Papillomavirus DNA and p53 , p21 Gene Expression in CIN3 and Uterine Cervical Cancer

Na JH, Choi HS

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):100-109.
PURPOSE: Though the etiology of this cancer has not been elucidated, it has been suggested that certain types of human papillomavirus (HPV) and alteration of the p53 gene are closely associated with...
The Role of Transbronchial Needle Aspiration for Diagnosis of Bronchogenic Carcinoma

Kim KY, Park JY, Cha SI, Park KS, Kang TK, Kim CH, Jung TH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):93-99.
PURPOSE: Transbronchial needle aspiration (TBNA) has been used for the diagnosis and staging of bronchogenic carcinoma through the flexible bronchoscope. The aim of this study was to investigate the diagnostic role of TBNA...
Combination Chemotherapy with VP - 16 , Ifosfamide , and Cisplatin ( VIP ) in the Advanced Non - Small Cell Lung Cancer

Cho YS, Kim SY, Kim JH, Yoon HJ, Cho KS

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):86-92.
PURPOSE: We conducted a phase II study in previously untreated patients with unresectable stage IIIB or IV non-small cell lung cancer to evaluate the response rate and toxicity of the combination chemotherapy regimen...
The Significance of Bone Marrow Micrometastasis ( BMM ) in Breast Carcinoma

Kang SH, Lee SJ, Kim SW, Kwun KB

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):76-85.
PURPOSE: This study was performed to determine the incidence of BMM and to correlate the presence of these micrometastases with prognosis and othet clinicopathologic features. Materials AND Methods: BMM was evaluated in 220 breast...
Personal Experience of 1,000 Breast Cancer Surgeries in Korea

Ahn SH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):68-75.
PURPOSE: A specialized breast surgeon is important to give comprehensive treatments to breast cancer patients. The purpose of this study was to evaluate the characteristics and treatment results of breast cancer patients in...
Expression Pattern and Prognostic Correlation of BAG - 1 Protein in Breast Cancer

Cho SH, Lee DY, Kim BJ, Hong SH

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):60-67.
PURPOSE: The objective of this study was to understand the expression of BAG-1 in the human breast cancer. MATERIALS AND METHODS: We studied its expression in one hundred and thirteen patients diagnosed...
Clinical Significance of Urokinase - type Plasminogen Activator Receptor ( uPAR ) Expression in Breast Cancer Tissues

Gong SJ, Rha SY, Jung HC, Park JO, Yoo NC, Roh JK, Yang WI, Lee KS, Min JS, Kim BS, Chung HC

  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):53-59.
PURPOSE: Cancer invasion is induced by several proteolytic enzyme systems associated with the destruction of basement membrane and extracellular matrix. Urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor-1 (PAI-1) have been reported as...

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