- Xylazole inhibits NO-cGMP pathway in fetal rat nerve cells
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Wang X, Wu Y, Liu L, Bai H, Zhang Z, Zhao M, Ma T, Song X, Jia L, Lv L, Yu Y, Xu X, Chen H, Gao L
- KMID: 2525540
- J Vet Sci.
- 2022 Jan;23(1):e16.
- doi: 10.4142/jvs.21188
Background: Xylazole (Xyl) is a veterinary anesthetic that is structurally and functionally similar to xylazine. However, the effects of Xyl in vitro remain unknown. Objectives: This study aimed to investigate the... -
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- miR-379 Inhibits Cell Proliferation, Invasion, and Migration of Vascular Smooth Muscle Cells by Targeting Insulin-Like Factor-1
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Li K, Wang Y, Zhang A, Liu B, Jia L
- KMID: 2374211
- Yonsei Med J.
- 2017 Jan;58(1):234-240.
- doi: 10.3349/ymj.2017.58.1.234
PURPOSE: MicroRNAs are small non-coding RNAs that play important roles in vascular smooth muscle cell (VSMC) function. This study investigated the role of miR-379 on proliferation, invasion, and migration of... -
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- Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma
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Liu Y, Jia L, Liu ZC, Zhang H, Zhang PJ, Wan Q, Wang R
- KMID: 756208
- Exp Mol Med.
- 2009 Sep;41(9):648-655.
- doi: 10.3858/emm.2009.41.9.071
Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial hypocontractility is the major underlying mechanism,... -
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- Baveno-VII criteria to predict decompensation and initiate non-selective beta-blocker in compensated advanced chronic liver disease patients
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Wong YJ, Zhaojin C, Tosetti G, Degasperi E, Sharma S, Agarwal S, Chuan L, Huak CY, Jia L, Xiaolong Q, Saraya A, Primignani M
- KMID: 2538210
- Clin Mol Hepatol.
- 2023 Jan;29(1):135-145.
- doi: 10.3350/cmh.2022.0181
Background/Aims: The utility of Baveno-VII criteria of clinically significant portal hypertension (CSPH) to predict decompensation in compensated advanced chronic liver disease (cACLD) patient needs validation. We aim to validate the... -
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- Synergistic Effect of Bone Marrow-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma in Streptozotocin-Induced Diabetic Rats
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Lian Z, Yin X, Li H, Jia L, He X, Yan Y, Liu N, Wan K, Li X, Lin S
- KMID: 2265691
- Ann Dermatol.
- 2014 Feb;26(1):1-10.
- doi: 10.5021/ad.2014.26.1.1
BACKGROUND: Diabetic wounds are a major clinical challenge, because minor skin wounds can lead to chronic, unhealed ulcers and ultimately result in infection, gangrene, or even amputation. Studies on bone... -
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