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Inhibition of lyosphosphatidic acid receptor 1 signaling in periodontal ligament stem cells reduces inflammatory paracrine effect in primary astrocyte cells

Kim DH, Seo EJ, Kim YH, Jang IH

Lysophosphatidic acid (LPA) is a bioactive lipid messenger involved in the pathogenesis of chronic inflammation and various diseases. Recent studies have shown an association between periodontitis and neuroinflammatory diseases such...
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Increased SOX2 expression in three-dimensional sphere culture of dental pulp stem cells

Seo EJ, Jang IH

Mesenchymal stem cells in the dental pulp exhibit a tendency for differentiation into various dental lineages and hold great potential as a major conduit for regenerative treatment in dentistry. Although...
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The role of lysophosphatidic acid receptor 1 in inflammatory response induced by lipopolysaccharide from Porphyromonas gingivalis in human periodontal ligament stem cells

Kim DH, Seo EJ, Tigyi GJ, Lee BJ, Jang IH

Lysophosphatidic acid (LPA) is a lipid messenger mediated by G protein-coupled receptors (LPAR1-6). It is involved in the pathogenesis of certain chronic inflammatory and autoimmune diseases. In addition, it controls...
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Clear cell odontogenic carcinoma: a mini review

Kim YH, Seo EJ, Park JK, Jang IH

Clear cell odontogenic carcinoma (CCOC), a very rare neoplasm located mostly in the mandible, has been regarded as a benign tumor. However, due to the accumulation of case reports, CCOC...
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Performance Evaluation of Newly Developed Korean Antimicrobial Susceptibility Testing Panels for MicroScan System Using Clinical Isolates from Teaching Hospitals in Korea

Kang DY, Hong JS, Park BY, Jang IH, Kim D, Lee H, Jeong SH

BACKGROUND: Antimicrobial resistant continues to pose a threat to public health. Therefore, rapid and accurate antimicrobial susceptibility testing is very important. The objectives of this study were to evaluate the...
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Performance Evaluation of SENTiFIT 270 and FOB Gold Reagent for Detecting Fecal Occult Blood

Kang DY, Kim D, Kim K, Jang IH, Jeong SH

BACKGROUND: Fecal occult blood tests have been widely used to screen for colorectal cancer. SENTiFIT 270 (Sentinel diagnostics, Italy) is a fecal occult blood test with an immunochemical method that...
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Differentiation of CD31-Positive Vascular Endothelial Cells from Organoid Culture of Dental Pulp Stem Cells

Seo EJ, Park JK, Jeong H, Kang JS, Kim HR, Jang IH

The mesenchymal stem cells (MSCs) that reside in dental tissues hold a great potential for future applications in regenerative dentistry. In this study, we used human dental pulp cells, isolated...
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Trib2 regulates the pluripotency of embryonic stem cells and enhances reprogramming efficiency

Do EK, Park JK, Cheon HC, Kwon YW, Heo SC, Choi EJ, Seo JK, Jang IH, Lee SC, Kim JH

Embryonic stem (ES) cells are pluripotent cells characterized by self-renewability and differentiation potential. Induced pluripotent stem (iPS) cells are ES cell-equivalent cells derived from somatic cells by the introduction of...
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Role of TAZ in Lysophosphatidic Acid-Induced Migration and Proliferation of Human Adipose-Derived Mesenchymal Stem Cells

Mo WM, Kwon YW, Jang IH, Choi EJ, Kwon SM, Kim JH

Transcriptional co-activator with a PDZ-binding motif (TAZ) is an important factor in lysophosphatidic acid (LPA)-induced promotion of migration and proliferation of human mesenchymal stem cells (MSCs). The expression of TAZ...
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Crucial role of HMGA1 in the self-renewal and drug resistance of ovarian cancer stem cells

Kim DK, Seo EJ, Choi EJ, Lee SI, Kwon YW, Jang IH, Kim SC, Kim KH, Suh DS, Seong-Jang K, Lee SC, Kim JH

Cancer stem cells are a subpopulation of cancer cells characterized by self-renewal ability, tumorigenesis and drug resistance. The aim of this study was to investigate the role of HMGA1, a...
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The Relationship Among Obesity, Benign Prostatic Hyperplasia and Erectile Dysfunction in Korea Men

Suh JS, Cho JH, Jeong WS, Ha US, Bae JH, Kim TH, Kim JH, Lee SH, Cho HJ, Yoo KH, Lee HL, Jang IH, Lee SW, Chung JH

PURPOSE: Pathogenically, both erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) are closely related to vascular problems, and vascular problems are closely associated with obesity. This study evaluated the relationships...
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Annual Report on External Quality Assessment Scheme for Clinical Microbiology in Korea (2014)

Ko YJ, Kim MN, Kim EC, Shin JH, Lee NY, Kim S, Jeong SH, Kim JS, Kim CK, Bae HG, Yoon NS, Joo SI, Hwang YY, Kim K, Jang IH, Heo J, Clinical Microbiology Subcommittee, Korean Association of External Quality Assessment Service

Annual proficiency surveys were performed in March, June and September 2014 by clinical microbiology division of The Korean Association of Quality Assurance for Clinical Laboratory. Parasitology part has been newly...
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Detection of Carbapenemases in Clinical Enterobacteriaceae Isolates Using the VITEK AST-N202 Card

Bae IK, Kang HK, Jang IH, Lee W, Kim K, Kim JO, Jeong SH, Lee K

BACKGROUND: The rapid and accurate detection of carbapenemase-producing Enterobacteriaceae (CPE) in clinical microbiology laboratories is essential for the treatment and control of infections caused by these microorganisms. This study was...
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Epidemiology and Characteristics of Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa

Hong DJ, Bae IK, Jang IH, Jeong SH, Kang HK, Lee K

Metallo-beta-lactamase-producing Pseudomonas aeruginosa (MPPA) is an important nosocomial pathogen that shows resistance to all beta-lactam antibiotics except monobactams. There are various types of metallo-beta-lactamases (MBLs) in carbapenem-resistant P. aeruginosa including...
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Evaluation of Blood Culture System for Culture of Body Fluids

Park SD, Uh Y, Jang IH, Hong M, Lee HG, Lee KS, Lee DH

BACKGROUND: Invasive and life-threatening infections such as meningitis, pericarditis, peritonitis, empyema, and septic arthritis are diagnosed via culture of relevant body fluids (BFs). The blood culture system (BCS) has been...
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Annual Report on External Quality Assessment Scheme in Clinical Microbiology in Korea (2013)

Ko YJ, Kim MN, Kim EC, Shin JH, Lee NY, Kim S, Jeong SH, Kim JS, Kim CK, Bae HG, Yoon NS, Joo SI, Hwang YY, Kim K, Jang IH, Heo J, Clinical Microbiology Subcommitte, The Korean Association of Quality Assurance for Clinical Laboratory

Annual external quality assessment was performed three times for clinical microbiology division of The Korean Association of Quality Assurance for Clinical Laboratory. For each trial, three sets composed of different...
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Factors Influencing the False Positive Signals of Continuous Monitoring Blood Culture System

Uh Y, Jang IH, Park SD, Kim KS, Seo DM, Yoon KJ, Choi HK, Kim YK, Kim HY

BACKGROUND: The false positive signals of a continuous monitoring blood culture system (CMBCS) increase the reporting time and laboratory cost. This study aimed to determine the highly relevant variables that...
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First Report of Nocardia farcinica Bursitis in a Patient with Diabetes Mellitus

Park SD, Kim HJ, Jang IH, Uh Y, Kim J, Yoon KJ, Oh JR

No abstract available.
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Molecular Characteristics of blaOXA-23-Producing Acinetobacter baumannii Isolated from a University Hospital

Jang IH, Park SD, Uh Y, Lee GS, Kim JB, Choi I

BACKGROUND: Multi-drug resistant (MDR) Acinetobacter baumannii has emerged as a significant infectious agent in hospitals worldwide. The purpose of this study was to determine the molecular characterization of MDR A....
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The Prevalence of Vaginal Microorganisms in Pregnant Women with Preterm Labor and Preterm Birth

Choi SJ, Park SD, Jang IH, Uh Y, Lee A

BACKGROUND: To investigate the risk factors for vaginal infections and antimicrobial susceptibilities of vaginal microorganisms among women who experienced preterm birth (PTB), we compared the prevalence of vaginal microorganisms between...
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