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Crosstalk between the heart and peripheral organs in heart failure

Jahng JW, Song E, Sweeney G

Mediators from peripheral tissues can influence the development and progression of heart failure (HF). For example, in obesity, an altered profile of adipokines secreted from adipose tissue increases the incidence...
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Highly Palatable Food during Adolescence Improves Anxiety-Like Behaviors and Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Rats that Experienced Neonatal Maternal Separation

Lee JH, Kim JY, Jahng JW

BACKGROUND: This study was conducted to examine the effects of ad libitum consumption of highly palatable food (HPF) during adolescence on the adverse behavioral outcome of neonatal maternal separation. METHODS: Male...
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cAMP/PKA Agonist Restores the Fasting-Induced Down-Regulation of nNOS Expression in the Paraventricular Nucleus

Yoo SB, Lee S, Lee JY, Kim BT, Lee JH, Jahng JW

Gene expression of neuronal nitric oxide synthase (nNOS) changes in the hypothalamic paraventricular nucleus (PVN) depending on feeding conditions, which is decreased during food deprivation and restored by refeeding, and...
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Effects of oropharyngeal taste stimuli in the restoration of the fasting-induced activation of the HPA axis in rats

Yoo SB, Lee JH, Ryu V, Jahng JW

INTRODUCTION: This study examined the regulatory mechanism underlying the meal-induced changes in the hypothalamic-pituitary-adrenal gland (HPA) axis activity. MATERIALS AND METHODS: Male Sprague-Dawley rats (250-300 g) were hired for two different...
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Absorbable Guided Bone Regeneration Membrane Fabricated from Dehydrothermal Treated Porcine Collagen

Pang KM, Choung HW, Kim SP, Yang EK, Kim KH, Kim SM, Kim MJ, Jahng JW, Lee JH

  • KMID: 1449184
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Mar;33(2):112-119.
PURPOSE: Collagen membranes are used extensively as bioabsorbable barriers in guided bone regeneration. However, collagen has different effects on tissue restoration depending on the type, structure, degree of cross-linking and...
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5-hydroxy-L-tryptophan Suppressed Food Intake in Rats Despite an Increase in the Arcuate NPY Expression

Moon YW, Choi SH, Yoo SB, Lee JH, Jahng JW

This study was conducted to define the underlying mechanism of hypophagia induced by increased central serotonergic action. Rats received 3 daily injections of 5-hydroxy-L-tryptophan (5-HTP), a serotonin precursor, at a...
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Effects of Saccharin Intake on Hippocampal and Cortical Plasticity in Juvenile and Adolescent Rats

Park JS, Yoo SB, Kim JY, Lee SJ, Oh SB, Kim JS, Lee JH, Park K, Jahng JW, Choi SY

The sensory system is developed and optimized by experiences given in the early phase of life in association with other regions of the nervous system. To date, many studies have...
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Experience of Neonatal Maternal Separation May Lead to a Long-term Modulation in the Neuronal Activity of Nucleus Accumbens in the Offspring

Ryu V, Yoo SB, Kim BT, Lee JH, Jahng JW

Dysfunction of the nucleus accumbens (NAcb) is implicated in the development of anhedonia, a core symptom of major depressive disorder. In order to define the neural basis of depression-like behaviors...
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Bone Regeneration with MMP sensitive hyaluronic acid-based hydrogel, rhBMP-2 and nanoparticles in rat calvarial critical size defect(CSD) model

Park JC, Yu SB, Chung YI, Tae GY, Kim JJ, Park YD, Jahng JW, Lee JH

  • KMID: 2398980
  • J Korean Assoc Oral Maxillofac Surg.
  • 2009 Jun;35(3):137-145.
As an efficient controlled release system for rhBMP-2, a functional nanoparticle-hydrogel complex, incorporated with matrix metalloproteinase( MMP) sensitive peptide cross-linker, was developed and used as a bone transplant. In vivo...
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Sinus floor grafting using calcium phosphate nano-crystal coated xenogenic bone and autologous bone

Pang KM, Li B, Alrashidan M, Yoo SB, Sung MA, Kim SM, Jahng JW, Kim MJ, Ko JS, Lee JH

  • KMID: 2136961
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2009 May;31(3):243-248.
PURPOSE: Rehabilitation of the edentulous posterior maxilla with dental implants often poses difficulty because of insufficient bone volume caused by pneumatization of the maxillary sinus and by crestal bone resorption....
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The Brainstem Area Postrema may Not be Involved in Lithium-induced Activation of the Hypothalamic-pituitary-adrenal Axis

Jahng JW, Spencer CM, Davidson A, Lee JH, Houpt TA

The brainstem area postrema (AP) has been suggested to be one potential site of lithium's action. In order to determine whether the AP, as a central action site of lithium,...
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Effect of nerve growth factor gene injection on the nerve regeneration in rat lingual nerve crush-injury model

Gao EF, Chung HJ, Ahn KM, Kim SM, Kim YH, Jahng JW, Lee JH

  • KMID: 2058616
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2006 Sep;28(5):375-395.
PURPOSE: Lingual nerve (LN) damage may be caused by either tumor resection or injury such as wisdom tooth extraction, Although autologous nerve graft is sometimes used to repair the damaged...
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The most appropriate antimitotic treatment of Ara-C in schwann cell-enriched culture from dorsal root ganglia of new born rat

Kim SM, Jahng JW, Lee JH

  • KMID: 2190357
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Feb;32(1):42-51.
Schwann cell, one of important components of peripheral nervous system, interact with neurons to mutually support the growth and replication of embryonal nerves and to maintain the different functions of...
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Change of taste preference and taste bud after unilateral lingual nerve transection in rat

Kim YT, Jeon SH, Yeom HR, Kang JH, Ahn KM, Kim SM, Jahng JW, Park KP, Lee JH

  • KMID: 1575888
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Dec;31(6):515-525.
PURPOSE OF STUDY: Lingual nerve damage can be caused by surgery or trauma such as physical irriatation, radiation, chemotherapy, infection and viral infection. Once nerve damage occurred, patients sometimes complain...
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Long-term analysis of reconstructed temporomandibular joint and mandible using free fibular flap

Ahn KM, Chung HJ, Ryom HR, Kim HJ, Kim YT, Hwang SJ, Myoung H, Kim MJ, Kim SM, Jahng JW, Lee JH

  • KMID: 2043808
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Oct;31(5):409-416.
PURPOSE OF STUDY: The temporomandibular joint (TMJ) occupies a key functional role in mastication and contributes to normal deglutition, speech as well as cosmesis. When a large amount of mandible...
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Sciatic nerve regeneration using calcium phosphate coated conduit and brain-derived neurotrophic factor gene-transfected schwann cell in rat

Choi WJ, Ahn KM, Hwang SJ, Choung PH, Kim MJ, Kim NY, Yoo SB, Jahng JW, Kim HM, Kim JS, Kim YH, Kim SM, Oh SJ, Kim SJ, Yang BE, Lee JH

  • KMID: 2190384
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Jun;31(3):199-218.
PURPOSE OF STUDY: Peripheral nerve regeneration depends on neurotrophism of distal nerve stump, recovery potential of neuron, supporting cell like Schwann cell and neurotrophic factors such as BDNF. Peripheral nerve...
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Fabrication of myomucosal flap using cultured oral epithelium in rabbit model

Shin YM, Chung HJ, Ahn KM, Park HJ, Sung MA, Kim SM, Hwang SJ, Kim MJ, Jahng JW, Kim SP, Yang EK, Song KY, Lee JH

  • KMID: 2044661
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2005 May;27(3):226-237.
PURPOSE: Extensive defect of oral and maxillofacial area is usually reconstructed with composite flap including skin paddle. However, if the defects are lined with only skin components, the mucosa's role...
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Serotonin transporter mRNA expression in the dorsal raphe nucleus of a tumor bearing mouse

Jahng JW, Choi SH, Cha MJ, Kim NY, Hwang SJ, Lee JH

  • KMID: 1033103
  • Exp Mol Med.
  • 2005 Feb;37(1):65-69.
This study was conducted to determine if an oral squamous cell carcinoma alters mRNA expression of serotonin transporter (5-HTT) in the central nervous system. KB cell line derived from a...
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Peripheral nerve regeneration using polyglycolic acid conduit and brain-derived neurotrophic factor gene transfected Schwann cells in rat sciatic nerve

Choi WJ, Ahn KM, Gao EF, Shin YM, Kim YT, Hwang SJ, Kim NY, Kim MJ, Jo SW, Kim BS, Kim YH, Kim SM, Oh SJ, Kim SJ, Jahng JW, Lee JH

  • KMID: 2400591
  • J Korean Assoc Oral Maxillofac Surg.
  • 2004 Dec;30(6):465-473.
PURPOSE: The essential triad for nerve regeneration is nerve conduit, supporting cell and neurotrophic factor. In order to improve the peripheral nerve regeneration, we used polyglycolic acid(PGA) tube and brain-derived...
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Fasting-induced Down-regulation of NADPH-diaphorase in the Magnocellular PVN of Rats

Lee JY, Kang DW, Kim DG, Jahng JW

In this study, we examined if glucocorticoids are required for the fasting-induced decrease of neuronal nitric oxide synthase (nNOS) in the magnocellular division of the paraventricular nucleus (PVN). Rats were...
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