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Plasma Fibroblast Growth Factor 23 Concentration Is Associated with Intracranial Cerebral Atherosclerosis in Acute Ischemic Stroke Patients

Chang Y, Kim J, Woo HG, Ryu DR, Oh HJ, Song TJ

BACKGROUND AND PURPOSE: Fibroblast growth factor 23 (FGF23) is associated with atherosclerosis via nitric-oxide-associated endothelial dysfunction and calcium-phosphate-related bone mineralization. This study aimed to determine the association of the plasma...
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Simultaneous Nonaneurysmal Subarachnoid Hemorrhage and Acute Cerebral Infarction in a Patient with Intracranial Atherosclerosis

Bae H, Park J, Kang S, Yun U, Ha SW, Kim SM

No abstract available.
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Characteristics of Acute Cerebral Infarction in Patients with Familial Hypercholesterolemia

Kim J, Park SH, Kim JM, Lee SH, Park KY

BACKGROUND: The patients with familial hypercholesterolemia (FH) suffer from early onset atherosclerotic vascular disease due to high level of cholesterol and subsequent vascular inflammation, especially in the form of coronary...
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Cigarette Smoking Preferentially Affects Intracranial Vessels in Young Males: A Propensity-Score Matching Analysis

Song Y, Lee D, Suh DC, Kim JG, Kim JK, Han M, Liu H, Zhao L, Kim EH, Jung SC, Lee DG, Koo HJ, Kim MJ, Baek S, Hwang SM, Kim BJ, Kim YJ, Cho HJ, Kim SJ, Jeon SB, Kim JS

PURPOSE: Cigarette smoking (CS) is one of the major risk factors of cerebral atherosclerotic disease, however, its level of contribution to extracranial and intracranial atherosclerotic stenosis (ECAS and ICAS) was...
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Efficiency of Air Bubble Removal in Preparation of Low-Profile Angioplasty Balloon Catheter: Bench-Top Comparison of Six Methods

Choi JH, Hwang SM, Lee DH

PURPOSE: Complete removal of air bubbles from balloons for neurovascular angioplasty is cumbersome. We compared the preparation difficulty, air removal efficiency, and air collection pattern of six different balloon catheter...
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Intracranial Arterial Calcificationes Can Reflect Cerebral Atherosclerosis Burden

Kim JM, Park KY, Bae JH, Han SH, Jeong HB, Jeong D

BACKGROUND AND PURPOSE: We investigated whether the intracranial arterial calcification status reflects the overall cerebral atherosclerosis burden. METHODS: Patients with acute cerebral infarction who were admitted to a single university hospital...
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Correlation of Adventitial Vasa Vasorum with Intracranial Atherosclerosis: A Postmortem Study

Zheng L, Yang WJ, Niu CB, Zhao HL, Wong KS, Leung TW, Chen XY

BACKGROUND AND PURPOSE: Vasa vasorum (VV) have been believed to be rare or non-existent in small-caliber intracranial arteries. In a series of human cerebral artery specimens, we identified and examined...
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Intracranial Large Artery Disease of Non-Atherosclerotic Origin: Recent Progress and Clinical Implications

Bang OY, Toyoda K, Arenillas , Liu L, Kim JS

Intracranial large artery disease (ILAD) is the major cause of stroke worldwide. With the application of recently introduced diagnostic techniques, the prevalence of non-atherosclerotic ILAD is expected to increase. Herein,...
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The Added Prognostic Value of Intracranial Artery Morphology to Predict Non-Cardioembolic Ischemic Stroke

Han NH, Jang J, Byun H, Lee K, Koo J, Choi HS, Jung SL, Ahn KJ, Kim BS

PURPOSE: To assess the added prognostic value of the morphologic characteristics of intracranial arteries in the risk modeling of a future non-cardioembolic stroke. MATERIALS AND METHODS: This retrospective study included 86...
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Ethnic Differences in Intracranial Artery Tortuosity: A Possible Reason for Different Locations of Cerebral Atherosclerosis

Kim BJ, Lee KM, Lee SH, Kim HG, Kim EJ, Heo SH, Chang DI, Kim JS

No abstract available.
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Angioplasty, Stenting and Other Potential Treatments of Atherosclerotic Stenosis of the Intracranial Arteries: Past, Present and Future

Wabnitz A, Chimowitz

Although there is an intuitive appeal to treat symptomatic stenotic intracranial arteries with endovascular therapies such as angioplasty and stenting, current data from randomized trials show intensive medical therapy is...
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Medical Treatment of Intracranial Atherosclerosis: An Update

Kim JS, Bang OY

For patients with symptomatic intracranial atherosclerosis (ICAS), antithrombotic agents are the mainstay of therapy. Anticoagulation (warfarin) is not widely used since it is not more effective than aspirin and carries...
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Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging

Yang WJ, Wong KS, Chen XY

Intracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of...
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Intracranial Atherosclerosis: Where Are We Now?

Kim JS

No abstract available.
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Diagnostic and Therapeutic Strategies for Acute Intracranial Atherosclerosis-related Occlusions

Lee JS, Hong JM, Kim JS

Intracranial atherosclerosis-related occlusion (ICAS-O) is frequently encountered at the time of endovascular revascularization treatment (ERT), especially in Asian countries. However, because baseline angiographic findings are similar between ICAS-O and embolism-related...
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Endovascular Therapy for Acute Basilar Artery Occlusion: Comparison between Patients with and without Underlying Intracranial Atherosclerotic Stenosis

Kim GS, Kim SK, Baek BH, Lee YY, Yoon W

PURPOSE: To compare the characteristics and outcomes of multimodal endovascular therapy (EVT) in patients with acute basilar artery occlusion (BAO) with and without underlying intracranial atherosclerotic stenosis (ICAS). MATERIALS AND METHODS:...
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Discrepancy between Angiography and Operative Findings of Small Side Wall Aneurysms in Atherosclerotic Parent Arteries

Sim SY

Preoperative evaluation of precise aneurysmal geometry is important for the treatment of intracranial aneurysms. We present two cases of unclippable side wall aneurysms due to their extremely low dome height,...
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Comparison of Four Methods calculating Ankle Brachial Indexes for Coexistent Intracranial and Extracranial Artery Stenoses in the Patients with Ischemic Stroke

Do Y, Park JH, Lee DK, An HK, Kwak SG, Do JK

BACKGROUND: The ankle brachial index (ABI) is a useful screening tool for peripheral arterial disease. It has been documented that the cerebral atherosclerosis is more frequent in stroke patients with...
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Intake of antioxidants and B vitamins is inversely associated with ischemic stroke and cerebral atherosclerosis

Choe H, Hwang JY, Yun JA, Kim JM, Song TJ, Chang N, Kim YJ, Kim Y

BACKGROUND/OBJECTIVES: This study was conducted to examine relationships between dietary habits and intakes of antioxidants and B vitamins and the risk of ischemic stroke, and to compare dietary factors according...
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Risk Factors for the Rupture of Bifurcation Intracranial Aneurysms Using CT Angiography

Wang GX, Zhang D, Wang ZP, Yang LQ, Zhang L, Wen L

PURPOSE: To investigate the clinical and morphological characteristics in relation to risk of bifurcation intracranial aneurysm rupture. MATERIALS AND METHODS: Data from 202 consecutive patients with 219 bifurcation aneurysms (129 ruptured...
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