- The Effect of 17beta- Estradiol on the Messenser Ribonucleic Acid ( mRNA ) Expression of Insulin-like Growth Factor Binding Proteins in Normal Myometrium and Uterine Leiomyoma
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Kim SS, Kim JK, Lee JY
- KMID: 1855595
- Korean J Obstet Gynecol.
- 1998 Jan;41(1):17-27.
Uterine leiomyoma is the most common female reproductive tract tumor during reproductive years. Estrogen has been implicated the most important factor in leimyoma growth. Recently studies have also implicated insulin-like... -
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- Insulin-Like Growth Factor Binding Proteins Profiles in Sera of Patients with Uterine Myoma Before and After Hystrectomy
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Noh KR, Kim JK
- KMID: 2260954
- Korean J Obstet Gynecol.
- 1998 May;41(5):1273-1283.
It has been suggested that insulin-like growth factor (IGF) system plays an pivotal role in the growth of uterine myoma. Recent reports have shown that serum IGF-I levels are normal... -
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- The Effect of Sex Steroid Hormone on the Expression of Insulin-Like Growth Factor Binding Preteins mRNA in the Explant Cultured from Human Uterine Myoma and Adjacent Normal Myometrium
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Lee JY, Kim JK, Seo CS, Kim SH, Choi YM, Moon SY
- KMID: 1853224
- J Korean Soc Endocrinol.
- 1998 Mar;13(1):34-44.
BACKGROUND: Sex steroid hormones are believed to play an important role in the genesis and growth of uterine myoma. Several studies suggest a possible role of insulin-like growth factor(IGF) as... -
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- The levels of insulin-like growth factor-binding proteins and their protease activity in serum and follicular fluid during the controlled ovarian hyperstimulation cycle
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Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee YH, Lee JY
- KMID: 2269998
- Korean J Obstet Gynecol.
- 2000 Mar;43(3):488-496.
OBJECTIVES: To evaluate changes in serum insulin-like growth factor binding protein(IGFBP)s profiles during the controlled hyperstimulation cycle and to compare IGFBPs profiles and their protease activity in follicular fluid(FF) from polycystic ovary... -
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- Insulin-Like Growth Factors and Their Bindign Proteins in Uterine Leiomyoma Pretreated with Gonadtropin Releasing Hormone Agonist
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Kim KC, Kim JG, Lee JY
- KMID: 1999282
- J Korean Soc Endocrinol.
- 1997 Sep;12(3):364-375.
BACKGROUND: Uterine leiomyoma is the most common pelvic tumor, occurring in 20-25% of women in reproductive age. Gonadotropin releasing hormone agonist (GnRHa) has been reognized as a temporary medical management... -
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- The Expression of Insulin-like Growth Factor (IGF), IGF- Binding Protein (IGFBP) and the Role of IGFBP-3 in the Korean Gastric Cancer Cell Lines
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Lee DY, Yi HK, Yang DH, Hwang PH
- KMID: 2174986
- J Korean Cancer Assoc.
- 2001 Apr;33(2):121-129.
PURPOSE: Insulin-like growth factor (IGF)-I and II are potent mitogens, postulated to exert autocrine and paracrine effects on growth regulation in human gastric cancer. In this study, we evaluated the... -
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- The Effects of a Gonadotropin Releasing Hormone agonist on Insulin-like Growth Factor Binding Proteins(IGFBPs) Production in Explant Cultures of Human Uterine Myoma and Normal Myometrium
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Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2260784
- Korean J Obstet Gynecol.
- 1997 Apr;40(4):758-766.
Gonadotropin releasing hormone agonist(GnRHa) has been used as a temporaruy medical management for uterine myoma. Insulin-like growth factors(IGFs) has been supposed to play an etiological role in myoma growth and... -
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- The Tumor Suppressor Function of PTEN/MMAC1 through the Regulation of IGFs and IGFBPs
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Yi HK, Hwang DJ, Kim SY, Lee DY, Hwang PH
- KMID: 1875814
- Korean J Pediatr.
- 2004 Aug;47(8):884-891.
PURPOSE: PTEN/MMAC1, a novel tumor suppressor gene, is mutated in a variety of advanced and metastatic cancers. It acts as a phosphatase, and thereby, regulates the PI-3 kinase/Akt pathway. In... -
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- The Role of Insulin-like Growth Factor I(IGF-I), and IGF Binding Protein (IGFBP) in Mouse Lung Cancer Cells
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Cho CH, Kim SK, Kwak SM, Chang J, Kim SK, Chung KY
- KMID: 2160197
- Tuberc Respir Dis.
- 2001 May;50(5):549-556.
- doi: 10.4046/trd.2001.50.5.549
BACKGROUND: IGF-I is an important mitogen in many types of malignancies. Tumors also express many IGF binding proteins, which modulate IGF action. The purpose of this study was to evaluaste... -
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- Insulin-like Growth Factor Binding Proteins(IGFBPs) Profiles in CordSera of Appropriate-for gestational Age, Small-for-gestational Age,Large-for-gestational Age Infant and Preterm Infant
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Kim JG, Ku SY, Kim SH, Choi YM, Shin CJ, Moon SY, Lee JY
- KMID: 2271653
- Korean J Obstet Gynecol.
- 1997 Mar;40(3):581-590.
The insulin-like growth factor(IGF) system consists of IGFs, their receptor and binding proteins(IGFBPs). The IGFs are important growth factors in the regulation of fetal growth. Since IGFBPs control IGF actions,... -
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- The Effect of Interleukin-1 on The Production of Insulin-Like Growth Factors and Their Binding Proteins in Human Granulosa-Luteal Cells
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Lee JY, Min EG, Kim JK, Suh CS, Kim SH, Choi YM, Moon SY
- KMID: 2261050
- Korean J Obstet Gynecol.
- 1998 Jul;41(7):1795-1804.
The relationship between the immune system and the endocrine system in the ovary has become of an challenging and exciting subject to reproductive scientists. The intraovarian regulators such as insulin-like... -
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- Expression of Human Insulin-Like Growth Factor Binding Protein ( IGFBP )-4 , 5 , 6 mRNA and Immunohistochemical Localization of IGFBP-4 in Human Fallopian Tube
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Choi DS, Lee JY
- KMID: 2260965
- Korean J Obstet Gynecol.
- 1998 May;41(5):1369-1383.
The fallopian tube is a dynamic structure where the epithelium undergoes sex steroid hormone-dependent specific changes and in which gamete transport, maturation, fertilization, and early embryo development and transport occur.... -
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- Study of the Mechanism for the Growth Inhibitory Effects of Conjugated Linoleic Acid on Caco-2 Colon Cancer Cells
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Oh EJ, Oh YS, Lee HS, Park HS, Yoon JH
- KMID: 2269651
- Korean J Nutr.
- 2003 Apr;36(3):270-279.
Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of linoleic acid (LA) and exhibits anticarcinogenic activity in a variety of animal models. We have previously observed... -
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- Antepartal insulin-like growth factor concentrations indicating differences in the metabolic adaptive capacity of dairy cows
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Piechotta , Holzhausen L, Araujo MG, Heppelmann M, Sipka A, Pfarrer C, Schuberth , Bollwein H
- KMID: 2155617
- J Vet Sci.
- 2014 Sep;15(3):343-352.
- doi: 10.4142/jvs.2014.15.3.343
Cows with different Insulin-like Growth Factor-I (IGF-I) concentrations showed comparable expression levels of hepatic growth hormone receptor (GHR). Suppressor of cytokine signaling 2 (SOCS2), could be responsible for additional inhibition... -
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- A differential gene expression profiles by cDNA microarrays in endometrioid endometrial carcinoma: a preliminary study
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Chung MJ, Chung EJ, Lee TH, Cho YL, Park IS, Lee YS
- KMID: 2244551
- Korean J Gynecol Oncol.
- 2007 Sep;18(3):219-226.
OBJECTIVE: Endometrial carcinoma is the most common gynecological malignant disease in industrialized countries. However, the molecular bases for endometrial tumoriogenesis are not clearly elucidated. Our hypothesis is that there may... -
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- Increased Activity of Insulin-like Growth Factor binding Protein-4 Protease in H-mole Patients
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Seo WS, Byun DW, Mok JO, Yoon JS, Kim YJ, Park HK, Kim CH, Kim SJ, Suh KI, Yoo MH, Lee HH, Rah SK
- KMID: 2200522
- J Korean Soc Endocrinol.
- 2004 Aug;19(4):346-357.
BACKGROUND: Hydatidiform mole (H-mole) is characterized by the neoplastic proliferation of trophoblasts. Only 1~10% of patients with partial H-mole will develop a trophoblastic tumor, but 18~29% of those with complete... -
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- Growth impairment of primary chondrocyte cells by serum of rats with chronic renal failure
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Mak RH, Chang SL, Pak YK
- KMID: 1097106
- Exp Mol Med.
- 2004 Jun;36(3):243-250.
Insulin-like growth factor (IGF)/IGF binding protein (IGFBP) abnormalities may be important in the pathogenesis of growth failure in chronic renal failure (CRF). We induced experimental CRF by 5/6 nephrectomy in... -
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- Gene Alterations of Ovarian Cancer Cells Expressing Estrogen Receptors by Estrogen and Bisphenol A Using Microarray Analysis
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Hwang KA, Park SH, Yi BR, Choi KC
- KMID: 2053658
- Lab Anim Res.
- 2011 Jun;27(2):99-107.
- doi: 10.5625/lar.2011.27.2.99
Since endocrine disrupting chemicals (EDCs) may interfere with the endocrine system(s) of our body and have an estrogenicity, we evaluated the effect(s) of bisphenol A (BPA) on the transcriptional levels... -
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