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Serum Insulin-like Growth Factor-1(IGF-1) and Insulin-like Growth Factor Binding Proteins in Hyperthyroidism and Hypothyroidism

Song HM, Park SS, Park TS, Baek HS, Lee DY

  • KMID: 2461604
  • J Korean Soc Endocrinol.
  • 1996 Mar;11(1):52-60.
Backgrounds: Thyroid hormones play a fundamental role in the initiation and maintenance of somatic growth in mammalian species, and the insulin-like growth factors(IGFs) occupy a position of central importance in...
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Recent Insights into Insulin-Like Growth Factor Binding Protein 2 Transcriptional Regulation

Shin M, Kang HS, Park JH, Bae JH, Song DK, Im SS

Insulin-like growth factor binding proteins (IGFBPs) are major regulators of insulin-like growth factor bioavailability and activity in metabolic signaling. Seven IGFBP family isoforms have been identified. Recent studies have shown...
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Profiles of Insulin-like Growth Factor[IGF]s , their Binding Protein[IGFBP]s and IGFBP-3 Protease Activity in Peritoneal Fluid of Patients with Endometriosis

Kim JK, Suh CS, Kim SH, Choi YM, Moon SY, Kang SB, Lee JY

  • KMID: 2269603
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):1011-1017.
OBJECTIVES: To test if IGF[insulin-like growth factor] components in peritoneal fluid[PF] of patients with endometriosis may be involved in the growth of ectopic endometrium. METHODS: In peritoneal fluid[PF] obtained from...
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Influence of Activin and Follistatin on Expression of Insulin-like Growth Factor (IGF)-I, II, Insulin-like Growth Factor Binding Protein (IGFBP)-1, 2, and 3 mRNA in Cultured Mouse Granulosa Cells

Chae HD, Hong SH, Cho YH, Oh YM, Lee BH, Kim SH, Kim CH, Kang BM

  • KMID: 2076847
  • Korean J Obstet Gynecol.
  • 2003 Mar;46(3):592-599.
OBJECTIVE: To investigate the influence of activin and follistatin on the expression of IGF (insulin-like growth factor)-I, II, IGFBP (insulin-like growth factor binding protein)-1, 2, and 3 mRNA in cultured...
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Evaluation of Serum Insulin-Like Growth Factor(IGF)-I, Insulin-Like Growth Factor Binding Protein(IGFBP)-2 and IGFBP-3 Levels in Healthy Korean Children

Yang GH, Jung HL, Kim DS, Shim JW, Shim JY, Park MS

  • KMID: 1979728
  • Korean J Pediatr.
  • 2005 Mar;48(3):298-305.
PURPOSE: We performed this study to evaluate the mean serum levels of insulin-like growth factor (IGF)-I, insulin-like growth factor binding protein(IGFBP)-2 and IGFBP-3 in healthy Korean children according to age...
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Insulin-Like Growth Factors and Their Bindign Proteins in Uterine Leiomyoma Pretreated with Gonadtropin Releasing Hormone Agonist

Kim KC, Kim JG, Lee JY

  • KMID: 1999282
  • J Korean Soc Endocrinol.
  • 1997 Sep;12(3):364-375.
BACKGROUND: Uterine leiomyoma is the most common pelvic tumor, occurring in 20-25% of women in reproductive age. Gonadotropin releasing hormone agonist (GnRHa) has been reognized as a temporary medical management...
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The Expression of Insulin-like Growth Factor (IGF), IGF- Binding Protein (IGFBP) and the Role of IGFBP-3 in the Korean Gastric Cancer Cell Lines

Lee DY, Yi HK, Yang DH, Hwang PH

  • KMID: 2174986
  • J Korean Cancer Assoc.
  • 2001 Apr;33(2):121-129.
PURPOSE: Insulin-like growth factor (IGF)-I and II are potent mitogens, postulated to exert autocrine and paracrine effects on growth regulation in human gastric cancer. In this study, we evaluated the...
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The Effects of a Gonadotropin Releasing Hormone agonist on Insulin-like Growth Factor Binding Proteins(IGFBPs) Production in Explant Cultures of Human Uterine Myoma and Normal Myometrium

Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee JY

  • KMID: 2260784
  • Korean J Obstet Gynecol.
  • 1997 Apr;40(4):758-766.
Gonadotropin releasing hormone agonist(GnRHa) has been used as a temporaruy medical management for uterine myoma. Insulin-like growth factors(IGFs) has been supposed to play an etiological role in myoma growth and...
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Insulin-like Growth Factor Binding Proteins(IGFBPs) Profiles in CordSera of Appropriate-for gestational Age, Small-for-gestational Age,Large-for-gestational Age Infant and Preterm Infant

Kim JG, Ku SY, Kim SH, Choi YM, Shin CJ, Moon SY, Lee JY

  • KMID: 2271653
  • Korean J Obstet Gynecol.
  • 1997 Mar;40(3):581-590.
The insulin-like growth factor(IGF) system consists of IGFs, their receptor and binding proteins(IGFBPs). The IGFs are important growth factors in the regulation of fetal growth. Since IGFBPs control IGF actions,...
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The relationship between serum insulin - like growth factor binding proteins profiles and bone mineral density in women without ovarian function

Moon SY, Choi YM, Kim SH, Lee JY, Kim JG, Shin CS, Suh CS, Kim SY

  • KMID: 2261271
  • Korean J Obstet Gynecol.
  • 1999 Jan;42(1):125-131.
The insulin-like growth factor(IGF)s are believed to play an important role in the maintenance of bone mass. The IGFs are found complexed with high affinity to a family of IGF-binding...
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Influence of Tumor Necrosis Factor-alpha on Expression of Insulin-like Growth Factor-II, Insulin-like Growth Factor Binding Protein-1, 2, 3, 5 in Cultured Human Luteinized Granulosa Cells

Hong SH, Hong SH, Kim SH, Chae HD, Kim CH, Kang BM

  • KMID: 2013163
  • Korean J Obstet Gynecol.
  • 2006 Mar;49(3):633-643.
OBJECTIVE: To investigate the influence of tumor necrosis factor (TNF)-alpha on the expression of insulin-like growth factor (IGF)-II, insulin-like growth factor binding protein (IGFBP)-1, 2, 3, and 5 mRNA in...
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Expression of the Insulin-like Growth Factor Binding Proteins (IGFBPs) in Colon Cancer

Kim CD, Lee JE, Kang BY, Lee RA, Kim KH

PURPOSE: The purpose of this study was to demonstrate the hypothesis that tussue IGFBP-2,-3, and -4 levels would differ between colon cancer tissue and adjacent normal tissue and to determine...
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Study of the Mechanism for the Growth Inhibitory Effects of Conjugated Linoleic Acid on Caco-2 Colon Cancer Cells

Oh EJ, Oh YS, Lee HS, Park HS, Yoon JH

  • KMID: 2269651
  • Korean J Nutr.
  • 2003 Apr;36(3):270-279.
Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of linoleic acid (LA) and exhibits anticarcinogenic activity in a variety of animal models. We have previously observed...
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Antepartal insulin-like growth factor concentrations indicating differences in the metabolic adaptive capacity of dairy cows

Piechotta , Holzhausen L, Araujo MG, Heppelmann M, Sipka A, Pfarrer C, Schuberth , Bollwein H

Cows with different Insulin-like Growth Factor-I (IGF-I) concentrations showed comparable expression levels of hepatic growth hormone receptor (GHR). Suppressor of cytokine signaling 2 (SOCS2), could be responsible for additional inhibition...
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Exploring upregulated genes during osteogenic differentiation of hMSCs

Ahn S, Rim J, Kwon J, Lee E, Jang H

  • KMID: 1485991
  • J Korean Assoc Oral Maxillofac Surg.
  • 2008 Feb;34(1):11-18.
Human bone marrow mesenchymal stem cells are thought to be multipotent cells, which are present in adult marrow, that can replicate as undifferentiated cells and that have the potential to...
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