- Demographics, Usage Patterns, and Safety of Male Users of Clomiphene in the United States
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Guo DP, Zlatev DV, Li S, Baker LC, Eisenberg
- KMID: 2471828
- World J Mens Health.
- 2020 Apr;38(2):220-225.
- doi: 10.5534/wjmh.190028
PURPOSE: The aim of this study was to characterize the demographics, usage patterns and complication rates of clomiphene use in male patients. MATERIALS AND METHODS: We retrospectively analyzed male patients from... -
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- Vitamin D and Male Fertility: An Updated Review
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Cito G, Cocci A, Micelli E, Gabutti A, Russo GI, Coccia ME, Franco G, Serni S, Carini M, Natali A
- KMID: 2471823
- World J Mens Health.
- 2020 Apr;38(2):164-177.
- doi: 10.5534/wjmh.190057
To date, the key role of vitamin D in male reproductive system has been suggested, since the expression of vitamin D receptors and metabolizing enzymes was demonstrated in the testis... -
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- Microtubular Dysfunction and Male Infertility
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Gunes S, Sengupta P, Henkel R, Alguraigari A, Sinigaglia MM, Kayal M, Joumah A, Agarwal A
- KMID: 2465406
- World J Mens Health.
- 2020 Jan;38(1):9-23.
- doi: 10.5534/wjmh.180066
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of... -
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- Misuse of testosterone replacement therapy in men in infertile couples and its influence on infertility treatment
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Song SH, Sung S, Her YS, Oh M, Shin DH, Lee J, Baek J, Lee WS, Kim DS
- KMID: 2469593
- Clin Exp Reprod Med.
- 2019 Dec;46(4):173-177.
- doi: 10.5653/cerm.2019.00290
OBJECTIVE: We investigated the clinical characteristics of men with testosterone replacement therapy (TRT)-induced hypogonadism and its effect on assisted reproductive technology (ART) in infertile couples. METHODS: This study examined the records... -
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- Improvement of Human Sperm Vacuolization and DNA Fragmentation Co-Cultured with Adipose-Derived Mesenchymal Stem Cell Secretome: In Vitro Effect
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Bader R, Ibrahim JN, Mourad A, Moussa M, Azoury J, Azoury J, Alaaeddine N
- KMID: 2465879
- Int J Stem Cells.
- 2019 Nov;12(3):388-399.
- doi: 10.15283/ijsc19047
BACKGROUND AND OBJECTIVES: Oxidative stress (OS) is known to be an important factor of male infertility. Adipose-derived mesenchymal stem cells (AD-MSCs) are known to have immune-modulatory and anti-oxidant effects through... -
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- The impact of two doses of coenzyme Q10 on semen parameters and antioxidant status in men with idiopathic oligoasthenoteratozoospermia
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Alahmar AT
- KMID: 2458498
- Clin Exp Reprod Med.
- 2019 Sep;46(3):112-118.
- doi: 10.5653/cerm.2019.00136
OBJECTIVE: Oxidative stress contributes to male infertility, and antioxidants have been recommended for treating idiopathic oligoasthenoteratozoospermia (OAT). There is, however, a lack of agreement on the type, dosing, and use... -
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- Investigation of the association of idiopathic male infertility with polymorphisms in the methionine synthase (MTR) gene
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Tanoomand , Hajibemani A, Abouhamzeh B
- KMID: 2458497
- Clin Exp Reprod Med.
- 2019 Sep;46(3):107-111.
- doi: 10.5653/cerm.2018.00423
OBJECTIVE: Spermatogenesis is a complex process that is regulated by a number of genes, some of which are involved in folate-dependent 1-carbon metabolism. Methionine synthase (encoded by MTR) is a... -
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- Validation of a smartphone-based, computer-assisted sperm analysis system compared with laboratory-based manual microscopic semen analysis and computer-assisted semen analysis
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Cheon WH, Park HJ, Park MJ, Lim MY, Park JH, Kang BJ, Park NC
- KMID: 2455966
- Investig Clin Urol.
- 2019 Sep;60(5):380-387.
- doi: 10.4111/icu.2019.60.5.380
PURPOSE: This study aimed to evaluate the clinical efficacy of a portable smartphone-based system for computer-assisted semen analysis (CASA) compared with the results of manual microscopic semen analysis (SA) and... -
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- Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility
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Agarwal A, Parekh N, Panner Selvam MK, Henkel R, Shah R, Homa ST, Ramasamy R, Ko E, Tremellen , Esteves S, Majzoub A, Alvarez JG, Gardner DK, Jayasena C, Ramsay JW, Cho CL, Saleh R, Sakkas D, Hotaling J, Lundy SD, Vij S, Marmar J, Gosalvez J, Sabanegh E, Park HJ, Zini A, Kavoussi P, Micic S, Smith R, Busetto GM, Bakırcıoğlu ME, Haidl G, Balercia G, Puchalt NG, Ben-Khalifa M, Tadros N, Kirkman-Browne J, Moskovtsev S, Huang X, Borges E, Franken D, Bar-Chama , Morimoto Y, Tomita K, Srini VS, Ombelet W, Baldi E, Muratori M, Yumura Y, La Vignera S, Kosgi R, Martinez M, Evenson DP, Zylbersztejn DS, Roque M, Cocuzza M, Vieira M, Ben-Meir A, Orvieto R, Levitas E, Wiser A, Arafa M, Malhotra V, Parekattil SJ, Elbardisi , Carvalho L, Dada R, Sifer C, Talwar P, Gudeloglu , Mahmoud AM, Terras K, Yazbeck C, Nebojsa B, Durairajanayagam D, Mounir A, Kahn LG, Baskaran S, Pai RD, Paoli D, Leisegang , Moein MR, Malik S, Yaman O, Samanta L, Bayane F, Jindal SK, Kendirci M, Altay B, Perovic D, Harlev A
- KMID: 2455407
- World J Mens Health.
- 2019 Sep;37(3):296-312.
- doi: 10.5534/wjmh.190055
Despite advances in the field of male reproductive health, idiopathic male infertility, in which a man has altered semen characteristics without an identifiable cause and there is no female factor... -
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- Does conventional freezing affect sperm DNA fragmentation?
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Le MT, Nguyen TT, Nguyen TT, Nguyen TV, Nguyen TA, Nguyen QH, Cao TN
- KMID: 2452645
- Clin Exp Reprod Med.
- 2019 Jun;46(2):67-75.
- doi: 10.5653/cerm.2019.46.2.67
OBJECTIVE: Sperm cryopreservation has been widely used in assisted reproductive technology, as it offers great potential for the treatment of some types of male infertility. However, cryopreservation may result in... -
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- Beta-carotene prevents the spermatogenic disorders induced by exogenous scrotal hyperthermia through modulations of oxidative stress, apoptosis, and androgen biosynthesis in mice
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Yon JM, Kim JS, Lin C, Park SG, Gwon LW, Lee JG, Baek IJ, Nahm SS, Nam SY
- KMID: 2451639
- Korean J Vet Res.
- 2019 Jun;59(2):59-67.
- doi: 10.14405/kjvr.2019.59.2.59
We investigated whether β-carotene (β-CA) or ellagic acid (EA), originating from various fruits and vegetables, has a preventive effect against male infertility induced by exogenous scrotal hyperthermia. ICR adult mice... -
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- C-Type Natriuretic Peptide/Natriuretic Peptide Receptor 2 Is Involved in Cell Proliferation and Testosterone Production in Mouse Leydig Cells
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Yang L, Lei L, Zhao Q, Gong Y, Guan G, Huang S
- KMID: 2443234
- World J Mens Health.
- 2019 May;37(2):186-198.
- doi: 10.5534/wjmh.180041
PURPOSE: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secretion in mouse Leydig cells. MATERIALS AND METHODS: Mouse testis of different postnatal stages... -
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- Traditional Chinese Medicine as a Remedy for Male Infertility: A Review
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Zhou SH, Deng YF, Weng ZW, Weng HW, Liu ZD
- KMID: 2443233
- World J Mens Health.
- 2019 May;37(2):175-185.
- doi: 10.5534/wjmh.180069
Male infertility (MI) is a complex multifactorial disease, and idiopathic infertility accounts for 30% of cases of MI. At present, the evidence for the effectiveness of empirical drugs is limited,... -
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- Recovery of Spermatogenesis Following Cancer Treatment with Cytotoxic Chemotherapy and Radiotherapy
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Okada K, Fujisawa M
- KMID: 2443232
- World J Mens Health.
- 2019 May;37(2):166-174.
- doi: 10.5534/wjmh.180043
The survival rates of boys and men with cancer have increased due to advances in cancer treatments; however, maintenance of quality of life, including fertility preservation, remains a major issue.... -
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- Finasteride and Erectile Dysfunction in Patients with Benign Prostatic Hyperplasia or Male Androgenetic Alopecia
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Shin YS, Karna KK, Choi BR, Park JK
- KMID: 2443231
- World J Mens Health.
- 2019 May;37(2):157-165.
- doi: 10.5534/wjmh.180029
Finasteride is primarily used to treat benign prostatic hyperplasia (BPH) and male androgenetic alopecia (MAA). Five-alpha reductase inhibitors (5α-RIs) could induce male sexual dysfunction due to their effects on testosterone... -
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- Epigenetics of Male Fertility: Effects on Assisted Reproductive Techniques
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Giacone F, Cannarella R, Mongioì L, Alamo A, Condorelli RA, Calogero A, La Vignera S
- KMID: 2443230
- World J Mens Health.
- 2019 May;37(2):148-156.
- doi: 10.5534/wjmh.180071
During the last decades the study of male infertility and the introduction of the assisted reproductive techniques (ARTs) has allowed to understand that normal sperm parameters do not always predict... -
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- Review of Guidelines for the Evaluation and Treatment of Leukocytospermia in Male Infertility
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Brunner RJ, Demeter JH, Sindhwani
- KMID: 2443228
- World J Mens Health.
- 2019 May;37(2):128-137.
- doi: 10.5534/wjmh.180078
Leukocytospermia is an ill-defined and poorly understood condition affecting up to 30% of male factor infertility. Current guidelines on leukocytospermia vary significantly, although it has been linked to increased rates... -
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- Metabolic Syndrome and Male Fertility
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Martins AD, Majzoub A, Agawal A
- KMID: 2443227
- World J Mens Health.
- 2019 May;37(2):113-127.
- doi: 10.5534/wjmh.180055
Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global... -
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- Evaluation of sperm DNA fragmentation using multiple methods: a comparison of their predictive power for male infertility
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Javed A, Talkad MS, Ramaiah MK
- KMID: 2469602
- Clin Exp Reprod Med.
- 2019 Mar;46(1):14-21.
- doi: 10.5653/cerm.2019.46.1.14
OBJECTIVE: The usual seminal profile has been customarily used for diagnosing male infertility based on an examination of semen samples. However, sperm DNA fragmentation has also been causally linked to... -
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- Testicular Fine-Needle Aspiration for Sperm Retrieval in Azoospermia: A Small Step toward the Technical Standardization
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Cito G, Coccia ME, Sessa F, Cocci A, Verrienti , Picone R, Fucci R, Criscuoli , Serni S, Carini M, Natali A
- KMID: 2429722
- World J Mens Health.
- 2019 Jan;37(1):55-67.
- doi: 10.5534/wjmh.180077
PURPOSE: The aim was to describe our preliminary experience performing testicular fine-needle aspiration (TEFNA) with a larger needle in infertile patients with obstructive azoospermia, and to provide a systematic literature... -
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