- Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice
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Imai J, Yahata T, Ichikawa H, Ibrahim AA, Yazawa M, Sumiyoshi , Inagaki Y, Matsushima M, Suzuki T, Mine T, Ando K, Miyata T, Hozumi K
- KMID: 2501387
- Intest Res.
- 2020 Apr;18(2):219-228.
- doi: 10.5217/ir.2019.00037
Background/Aims: Intestinal fibrosis is a major complication of Crohn’s disease (CD). The profibrotic protein transforming growth factor-β (TGF-β) has been considered to be critical for the induction of the fibrotic... -
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- Implantation of Bone Marrow Stromal Cell Sheets Derived from Old Donors Supports Bone Tissue Formation
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Akahane M, Shimizu T, Inagaki Y, Kira T, Egawa T, Okuda A, Onishi T, Imamura T, Tanaka Y
- KMID: 2405970
- Tissue Eng Regen Med.
- 2018 Feb;15(1):89-100.
- doi: 10.1007/s13770-017-0088-4
The purpose of this study was to evaluate the osteogenesis ability of osteogenic matrix cell sheets (OMCS) derived from old donor cells. Bone marrow stromal cells (BMSC) were obtained from... -
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- Serum matrix metalloproteinase-1 level represents disease activity as opposed to fibrosis in patients with histologically proven nonalcoholic steatohepatitis
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Ando W, Yokomori H, Tsutsui N, Yamanouchi E, Suzuki Y, Oda M, Inagaki Y, Otori K, Okazaki I
- KMID: 2429084
- Clin Mol Hepatol.
- 2018 Mar;24(1):61-76.
- doi: 10.3350/cmh.2017.0030
BACKGROUND/AIMS: Nonalcoholic steatohepatitis (NASH) is prevalent in both economically developed and developing countries. Twenty percent of NASH progresses to cirrhosis with/without hepatocellular carcinoma, and there is an urgent need to... -
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