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Acute Pancreatitis Caused by Dyslipidemia

An SB, Park SJ, Im SS, Sung MK, Lee BH, Lee JW, Park JH

Hyperlipidemia can be a cause of acute pancreatitis. For example, dyslipidemia classified Fredrickson/WHO classification type I, V can induce acute pancreatitis spontaneously. Secondary hyperlipidemia (DM, alcohol, estrogen, etc.) also can...
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Recent Insights into Insulin-Like Growth Factor Binding Protein 2 Transcriptional Regulation

Shin M, Kang HS, Park JH, Bae JH, Song DK, Im SS

Insulin-like growth factor binding proteins (IGFBPs) are major regulators of insulin-like growth factor bioavailability and activity in metabolic signaling. Seven IGFBP family isoforms have been identified. Recent studies have shown...
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Phloretin Ameliorates Succinate-Induced Liver Fibrosis by Regulating Hepatic Stellate Cells

Le CT, Nguyen G, Park SY, Dong HN, Cho YK, Lee JH, Im SS, Choi DH, Cho EH

Background: Hepatic stellate cells (HSCs) are the major cells which play a pivotal role in liver fibrosis. During injury, extracellular stimulators can induce HSCs transdifferentiated into active form. Phloretin showed...
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High Sodium Intake, as Assessed by Urinary Sodium Excretion, Is Associated with Nonalcoholic Fatty Liver Disease or Sarcopenia

Han E, Kim MK, Im SS, Kim HS, Kwon TK, Jang BK

Background/Aims: We explored whether high sodium intake, assessed by urinary excretion, determines the risk of sarcopenia and nonalcoholic fatty liver disease (NAFLD). Methods: We analyzed 10,036 adult participants with normal kidney...
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HNF1 and/or HNF3 may contribute to the tissue specific expression of glucokinase gene

Cha JY, Kim HI, Im SS, Li TZ, Ahn YH

  • KMID: 1085740
  • Exp Mol Med.
  • 2001 Jun;33(2):59-63.
A possible role of hepatocyte nuclear factor 1 (HNF1) or HNF3, a predominant trans-acting factors of hepatic or pancreatic beta-cells, was examined on the tissue specific interdependent expression of glucokinase...
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Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter

Im SS, Kim JW, Kim TH, Song XL, Kim SY, Kim HI, Ahn YH

  • KMID: 755748
  • Exp Mol Med.
  • 2005 Apr;37(2):101-110.
In the present study, we show that the expression of type 2 glucose transporter isoform (GLUT2) could be regulated by PPAR-gamma in the liver. Rosiglitazone, PPAR-gamma agonist, activated the GLUT2...
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