- Perinatal brain damage caused by cerebral hypoxia-ischemia
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Shin SM
- KMID: 1690685
- J Korean Pediatr Soc.
- 1993 Jan;36(1):1-8.
No abstract available. -
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- Hypoxia in Hepatocellular Carcinoma
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Myung SJ, Yoon JH
- KMID: 760700
- Korean J Hepatol.
- 2007 Mar;13(1):9-19.
Hepatocellular carcinoma (HCC) is characterized by hypervascularity, indicating that angiogenesis plays a vital role in HCC growth and progression. A number of anti-angiogenic therapies are being utilized in clinical trials... -
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- A Clinical Report for a Hypoxic Cerebral Hypoxia managed by Combination therapy with Thiopental Sodium and Low-grade Hypothermia
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Lee SM, Kim KM
- KMID: 2349519
- Korean J Anesthesiol.
- 1986 Oct;19(5):511-516.
The capacity of hypothermia to protect the brain during a period of decreased or absent oxygen delivery(hypoxia) is well established both experimentally and clinically. And also experimentally, barbiturates, which... -
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- Hypoxia-inducible factor 1, hepatocellular carcinoma and angiogenesis
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Kim JW
- KMID: 1717321
- Korean J Hepatol.
- 2010 Sep;16(3):278-279.
- doi: 10.3350/kjhep.2010.16.3.278
No abstract available. -
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- Acute Hypoxia Activates an ENaC-like Channel in Rat Pheochromocytoma (PC12) Cells
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Bae YJ, Yoo JC, Park N, Kang D, Han J, Hwang E, Park JY, Hong SG
- KMID: 1432764
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):57-64.
- doi: 10.4196/kjpp.2013.17.1.57
Cells can resist and even recover from stress induced by acute hypoxia, whereas chronic hypoxia often leads to irreversible damage and eventually death. Although little is known about the response(s)... -
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- Effect of Vitamin E on Cerebral Hypoxia-Ischemia in Neonatal Rats
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Seok JE, Oh YK, Park ST
- KMID: 1946204
- J Korean Pediatr Soc.
- 2001 Jul;44(7):764-772.
PURPOSE: In order to evaluate the hypoxia-ischemia induced neurotoxic effect and the protective effect of vitamin E as an antioxidant, cell number and cell viability were measured in cerebral neurons... -
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- Changes of 5-hydroxytryptamine release by different glucose concentration from hippocampal slices exposed to hypoxia
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Kang DW, Ahn YS
- KMID: 1123182
- Yonsei Med J.
- 1995 Jun;36(3):271-277.
- doi: 10.3349/ymj.1995.36.3.271
We have previously reported that the spontaneous release of [3H]5-hydroxytryptamine(5-HT) was markedly decreased by hypoxic insult in rat hippocampal slices. In the present study, the effect of glucose on 5-HT... -
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- The Relationship between Umbilical-Cerebral Doppler Ratio and Umbilical Artery Gas Analysis
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Won HS, Shin MS, Kang JA, Lee PY, Lee IS, Kim A, Mok JE
- KMID: 1855617
- Korean J Obstet Gynecol.
- 1998 Jan;41(1):200-204.
OBJECTIVES: To assess Doppler flow imaging to determine the relationship between umbilical-cerebral Doppler ratio and fetal hypoxia. To establish the cut-off value of umbilical-cerebral artery pulsatility index ratio for prediction... -
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- Hypoxia induces Wee1 expression and attenuates hydrogen peroxide-induced endothelial damage in MS1 cells
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Hong KS, Kim HS, Kim SH, Lim DJ, Park JY, Kim SD
- KMID: 1058702
- Exp Mol Med.
- 2011 Dec;43(12):653-659.
- doi: 10.3858/emm.2011.43.12.074
In an oxygen-depleted environment, endothelial cells initiate an adaptive pattern of synthesis, which may enable them to survive hypoxic crises. Using high-resolution two-dimensional gel electrophoresis in conjunction with mass spectroscopy,... -
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- Wheatgrass extract inhibits hypoxia-inducible factor-1-mediated epithelial-mesenchymal transition in A549 cells
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Do NY, Shin HJ, Lee JE
- KMID: 2412019
- Nutr Res Pract.
- 2017 Apr;11(2):83-89.
- doi: 10.4162/nrp.2017.11.2.83
BACKGROUND/OBJECTIVES: Epithelial-mesenchymal transition (EMT) is involved in not only cancer development and metastasis but also non-cancerous conditions. Hypoxia is one of the proposed critical factors contributing to formation of chronic... -
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- Role of HIF1α Regulatory Factors in Stem Cells
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Lee HJ, Jung YH, Choi GE, Kim JS, Chae CW, Han HJ
- KMID: 2447220
- Int J Stem Cells.
- 2019 Mar;12(1):8-20.
- doi: 10.15283/ijsc18109
Hypoxia-inducible factor 1 (HIF1) is a master transcription factor that induces the transcription of genes involved in the metabolism and behavior of stem cells. HIF1-mediated adaptation to hypoxia is required... -
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- Predicting Intraventricular Hemorrhage by the Nucleated Erythrocytes Counts in Preterm Neonates
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Jeon YS, Shin JS, Cheoh KC
- KMID: 1838610
- J Korean Soc Neonatol.
- 1998 Jun;5(1):35-39.
PURPOSE: Prolonged fetal hypoxia stimulates erythropoiesis in fetal life and induces increased nucleated erythrocytes(NRBC) counts at the early newborn period. To evaluate the relationship between prolonged fetal hypoxia and neonatal... -
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- Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy
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Yu T, Tang B, Sun X
- KMID: 2419104
- Yonsei Med J.
- 2017 May;58(3):489-496.
- doi: 10.3349/ymj.2017.58.3.489
Hypoxia is frequently observed in solid tumors and also one of the major obstacles for effective cancer therapies. Cancer cells take advantage of their ability to adapt hypoxia to initiate... -
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- Regulatory Role of Hypoxia Inducible Factor in the Biological Behavior of Nucleus Pulposus Cells
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Li H, Liang CZ, Chen QX
- KMID: 2158211
- Yonsei Med J.
- 2013 Jul;54(4):807-812.
- doi: 10.3349/ymj.2013.54.4.807
Intervertebral disc (IVD) degeneration is implicated as a major cause of low back pain. The alternated phenotypes, reduced cell survival, decreased metabolic activity, loss of matrix production and dystrophic mineralization... -
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- Serial MRI of Hypoxic Brain Damage after Hydrogen Sulfide Exposure
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Lee JH, Jeon BJ, Lee DS, Yoo BG, Kim MK, Kim MJ, Huh SY
- KMID: 2129327
- J Korean Neurol Assoc.
- 2015 Nov;33(4):334-337.
- doi: 10.17340/jkna.2015.4.18
Hydrogen sulfide is a colorless gas and frequently lethal occupational hazard that causes tissue hypoxia with prominent neurological signs. Depending on the amount of exposure, many neurotoxic effects such as... -
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- Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors
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Chen L, Endler A, Shibasaki
- KMID: 1099861
- Exp Mol Med.
- 2009 Dec;41(12):849-857.
- doi: 10.3858/emm.2009.41.12.103
The mechanisms that regulate angiogenesis in hypoxia or hypoxic microenvironment are modulated by several pro- and antiangiogenic factors. Hypoxia-inducible factors (HIFs) have been established as the basic and major inducers... -
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- E-selectin Mrna and Protein Expression Increase Transiently After Unilateral Cerebral hypoxia-ischemia in Neonatal Rats
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Eun BL
- KMID: 2177120
- J Korean Child Neurol Soc.
- 1998 May;5(2):228-234.
BACKGROUND AND PURPOSE: The selectins play a role in the initiation of endothelium-leukocyte interaction; endothelial expression of E-selectin is induced by ischemia-reperfusion-like conditions in vitro. Neutrophils accumulate in post-hypoxic-ischemic neonatal... -
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- Therapeutic Effect of Nimodipine in Neonatal Rat Model of Cerebral Hypoxia-Ischemia
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Hong IH, Kim HM
- KMID: 2207695
- J Korean Pediatr Soc.
- 1999 Nov;42(11):1552-1558.
PURPOSE: Recent studies suggest that nimodipine, a potent calcium-channel blocker, may improve neurological outcome after experimental hypoxia-ischemic brain injury. This study was conducted to evaluate the therapeutic effect of nimodipine... -
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- Power Spectral Analysis of Heart Rate Variability during Acute Hypoxia in Fetal Lamb
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Min SW, Ko H, Kim KW, Kim SD, Kim CS, Lee KH, Hwang EY
- KMID: 2033317
- Korean J Anesthesiol.
- 1997 Mar;32(3):336-347.
- doi: 10.4097/kjae.1997.32.3.336
BACKGROUND: The aim of the present study was to investigate the changes in the patterns of power spectrum of R-R interval variability on fetal lamb EKG during acute fetal hypoxia. METHODS:... -
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- The Neuroprotective Effects of the Platelet-Activating Factor Antagonist BN 52021 on Hypoxic-ischemic Brain Injury in the Immature Rat
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Eun BL
- KMID: 2329201
- J Korean Child Neurol Soc.
- 1997 Oct;5(1):9-22.
PURPOSE: Platelet-activating factor (PAF) is overproduced in ischemic brain. Although post-ischemic PAF antagonist administration protects the mature brain in some models, little is known about the effects of PAF antagonists... -
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