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Effect of Statin Use on Liver Cancer Mortality Considering Hypercholesterolemia and Obesity in Patients with Non-Cirrhotic Chronic Hepatitis B

Kim GA, Shim JJ, Lee JS, Kim BH, Kim JW, Oh CH, Oh CM, Oh IH, Park SY

Little is known about the benefits of statin use on liver cancer mortality among patients with chronic hepatitis B (CHB) considering hypercholesterolemia and obesity. A nationwide retrospective cohort study was...
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Efficacy and safety of alirocumab in Korean patients with hypercholesterolemia and high cardiovascular risk: subanalysis of the ODYSSEY-KT study

Nam CW, Kim DS, Li J, Baccara-Dinet MT, Li I, Kim JH, Kim CJ

BACKGROUND/AIMS: Efficacy and safety data of alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9), is not yet well established in the Korean population. We assessed...
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Lipoprotein X Detected in a Case of Hypercholesterolemia Associated With Chronic Cholangiohepatitis

Ha J, Lee SG, Kim JH

No abstract available.
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Hypercholesterolemia Is Associated with a Shorter Time to Castration-Resistant Prostate Cancer in Patients Who Have Undergone Androgen Deprivation Therapy

Jeon JC, Park J, Park S, Moon KH, Cheon SH, Park S

PURPOSE: The goal of this study was to investigate the association between hypercholesterolemia and the time required for progression to castration-resistant prostate cancer (CRPC) in patients who have undergone androgen...
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Dietary chitosan enhances hepatic CYP7A1 activity and reduces plasma and liver cholesterol concentrations in diet-induced hypercholesterolemia in rats

Moon MS, Lee MS, Kim CT, Kim Y

  • KMID: 2313310
  • Nutr Res Pract.
  • 2007 Sep;1(3):175-179.
The present study was performed to elucidate the hypocholesterolemic action of chitosan on the diet-induced hypercholesterolemia in rats. Male Sprague-Dawley rats (n=24) were fed with chitosan-free diet (Control), diets containing...
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Hypercholesterolemia; Management of Korean Patients in New Millennium

Kim CJ, Lee KJ

  • KMID: 2081275
  • Korean J Med.
  • 2007 Jun;72(6):580-592.
Cardioprotective effect and the safety of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) has been established in many large-scaled randomized controlled trials encompassing both primary and secondary prevention. Therefore, the market of...
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Effects of Ethanol Extract of Onion on the Lipid Profiles in Patients with Hypercholesterolemia

Nam KH, Baik HW, Choi TY, Yoon SG, Park SW, Joung H

  • KMID: 2259924
  • Korean J Nutr.
  • 2007 Apr;40(3):242-248.
It is known that onion increases antioxidative and antibiotic capacity, and decreases blood pressure and cholesterol levels. The study was carried out to investigate whether ethanol extract of onion can...
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Treatment Gap in the Management of Hypercholesterolemia in Korea: Return on Expenditure Achieved for LIpid TherapY (REALITY)

Kim SH, Park JS, Zo JH, Kim MA, Kim HS

BACKGROUND AND OBJECTIVES: Several studies have showed a large 'treatment gap' between clinical practice and the guidelines for treating hypercholesterolemia. There is little information on the real practice of managing...
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Ten centers' study on the present state of treatment for hypercholesterolemia in patients with coronary artery disease

Sung J, Kim SH, Kim YD, Baek SH, Ahn Y, Lim DS, Cho HK, Chae SC, Han KH, Kim HS

  • KMID: 2081149
  • Korean J Med.
  • 2005 Oct;69(4):371-378.
BACKGROUND: Previous studies showed 'treatment gap' phenomenon in the treatment of hyperlipidemia, meaning failure to adhere to the recommendation in the treatment guideline. In Korea, systematic research on this issue...
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The safety and efficacy of ezetimibe and simvastatin combination therapy in Korean patients with primary hypercholesterolemia

Bae JW, Kim HS, Lee SC, Han KH, Jeon ES

  • KMID: 2252431
  • Korean J Med.
  • 2005 May;68(5):487-497.
BACKGROUND: The prevalence of hypercholesterolemia in Korea is growing. In spite of the wide use of HMG-CoA reductase inhibitors (statins), some patients don't reach optimal cholesterol reduction and suffer hepatotoxicity...
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Changes in Coronary Flow Reserve Assessed by Transthoracic Echocardiography after Lipid-Lowering Therapy in Patients with Hypercholesterolemia

Kim MA, Sohn DW, Cho YS, Kim YJ, Park YB, Choi YS

BACKGROUND: The coronary flow reserve is known to be reduced in patients with hypercholesterolemia, and has also been reported to improve after lipid-lowering therapy. Using transthoracic Doppler echocardiography, the changes...
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The Effect of Atorvastatin on Serum Lipid Levels among Patients with Hypercholesterolemia

John SS, Park JH, Chung HJ, Son JC, Kim KM, Kim BT

  • KMID: 2253677
  • J Korean Acad Fam Med.
  • 2004 Jan;25(1):46-51.
BACKGROUND: Recently, the incidence of cardiovascular diseases has increased in Korea. Hypercho-lesterolemia is a major risk factor for cardiovascular diseases. Atorvastatin (Lipitor(R)) is prescribed for the treatment of hyperlipidemia in...
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Short Term Effects of Hypercholesterolemia on Corpus Cavernosal Tissue in Rabbits

Kwak KM, Seo SI, Hwang TK

  • KMID: 2293597
  • Korean J Urol.
  • 2003 Dec;44(12):1277-1282.
PURPOSE: To study the short term effects of hypercholesterolemia on corpus cavernosal tissue, we performed isometric tension studies and RT-PCR was used to identify mRNA expression of VEGF on isolated...
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The clinical and cost effectiveness of medical nutrition therapy in persons with hypercholesterolemia

Shon CM, Nho MR, Lee YH, Lim JH

  • KMID: 2332012
  • J Korean Diet Assoc.
  • 2003 Feb;9(1):32-39.
Although medical nutrition therapy (MNT) is considered as a cornerstone of medical treatment for hypercholesterolemia, few studies have evaluated medical and economical outcome of MNT. This study was conducted to...
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The Effect of Hypercholesterolemia and Hypertension on Long-term Renal Allograft Survival

Lee MR, Kim MY, Ha J, Kim SJ

  • KMID: 2026214
  • J Korean Surg Soc.
  • 2002 Dec;63(6):493-497.
PURPOSE: In kidney transplant recipients, chronic transplant nephropathy is the major cause of graft failure after the first posttransplant year. Because histological features of chronic transplant nephropathy closely resemble those...
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Comparison of Efficacy and Safety of Simvastatin, 10 mg and 20 mg in the Treatment of Hypercholesterolemia Patients Over 60-Year Old

Choi HJ, Lee W, Han KW, Kim HM, Lee JG, Lee HH, Won KH, Kim SY

  • KMID: 1742785
  • J Korean Geriatr Soc.
  • 2002 Dec;6(4):320-329.
BACKGROUND: Elevated serum cholesterol level is a major risk factor for cardiovascular morbidity and mortality. Simvastatin is effective for treating hypercholesterolemia. The aim of the study was to evaluate efficacy...
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Treatment of Hypercholesterolemia in Elderly Patients; From the Viewpoint of Statins

Choe SC, Lee S, Kim CJ

  • KMID: 1742778
  • J Korean Geriatr Soc.
  • 2002 Dec;6(4):253-260.
No abstract available.
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The Change of Cholesterol Level and IL-6, CRP in Unstable Angina Patients with Hypercholesterolemia after Low Dose Simvastatin Therapy

Chung SJ, Bae KS, Park SH

BACKGROUND AND OBJECTIVES: Cardiovascular mortality in patients with atherosclerosis can be reduced by treatment with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. This proven effect is probably due, not only to...
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Effect of Hypercholesterolemia and Age on Endothelial Function in Women

Park TJ, Seo BG, Choi DJ, Park SJ, Chin BC, Lee JH, Mun IG, Park JR

BACKGROUND AND OBJECTIVES: It is known that both hypercholesterolemia and aging cause endothelial dysfunction, but which has the greater effect is less well known. A useful, non-invasive method for the...
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Comparison of efficacy and safety of simvastatin, 10 mg and 20 mg in the treatment of hypercholesterolemia

Lee JG, Kim HM, Lee HH, Choi HJ, Park CH, Seo MD, Jeong JC, Cho HK, Choi SS, Lee JH, Kim SY, Lee WS

  • KMID: 2080859
  • Korean J Med.
  • 2002 Jul;63(1):46-53.
BACKGROUND: Elevated serum cholesterol level is a major risk factor for cardiovascular morbidity and mortality. Simvastatin is effective for treating hypercholesterolemia. The aim of the study was to evaluate efficacy...
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