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Metformin-loaded Citric Acid Cross-linked Agarose Films in the Prevention of Postoperative Abdominal Adhesion

Moon JH, Park JH, Jeong JH, Sung NS, Jeong YG, Song KC, Ahn JP, Lee NS, Han SY

Postoperative abdominal adhesion (PAA) causes significant long-term postoperative morbidity. Although numerous physical anti-adhesion barriers (AAB) are used as therapeutical interventions, none of them has achieved sustained success. As a potential...
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Bioactive characteristics of an implant surface coated with a pH buffering agent: an in vitro study

Pae HC, Kim SK, Park JY, Song YW, Cha JK, Paik JW, Choi SH

PURPOSE: The purpose of this study was to evaluate the effectiveness of conventional sandblasted, large-grit, acid-etched (SLA) surface coated with a pH buffering solution based on surface wettability, blood protein...
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The effects of saline soaking on the removal torque of titanium implants in rabbit tibia after 10 days

Park JH, Cho SA

PURPOSE: The aim of this study was to confirm if Laser-treated implants were soaked in 0.9% NaCl solution for 2 weeks could increase the surface hydrophilicity, and the Remoal Torque...
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Fabrication of rough surface on titanium using electrochemical treatment in NaCl electrolyte

Kim B, Lee WY, Park YJ, Song HJ

It is difficult to get sufficient roughness on titanium implant surface using traditional electrochemical treatments. In this study, we have developed a new method which provides a hybrid structured titanium...
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Surface characterization of calcium phosphate coating formed on chitosan and alkali-treaDted titanium metal

Park KH, Lee WY, Song HJ, Park YJ

The calcium phosphate coating on various pretreated metals was prepared by soaking in modified simulated body fluid (m-SBF) solution. The coating structure and its surface morphologies were determined by x-ray...
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A Comparison of the Effects of Silica and Hydroxyapatite Nanoparticles on Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone)/Chitosan Nanofibrous Scaffolds for Bone Tissue Engineering

Raeisdasteh Hokmabad V, Davaran S, Aghazadeh , Alizadeh E, Salehi R, Ramazani A

BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(ε-caprolactone)-poly(ethylene...
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Influence of Cell Surface Hydrophobicity on Adhesion and Biofilm Formation in Candida albicans and Several Bacterial Species

Park SJ, Lee KH

The purpose of this study is to investigate the correlation of cell surface hydrophobicity (CSH) and biofilm formation or adhesion in Candida albicans (C. albicans) and several pathogenic bacteria. All...
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Influence of Implant Surface Coated with pH Buffering Agent on Early Osseointegration

Kang JH, Kim SK, Pae HC, Park JY, Cha JK, Choi SH

PURPOSE: Surface treatment with pH buffering agent has been developed to achieve higher and faster osseointegration. The aim of this study was to evaluate its influence by measuring removal torque...
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Root canal irrigants influence the hydrophobicity and adherence of Staphylococcus epidermidis to root canal dentin: an in vitro study

Nagendrababu V, Sheriff Sultan O, Kannathasan S, Patel AS, Chitra E, Neelakantan P, Davamani F

OBJECTIVES: To determine the effect of root canal irrigants on the hydrophobicity and adherence of Staphylococcus epidermidis (S. epidermidis) to root canal dentin in vitro. MATERIALS AND METHODS: Root dentin blocks...
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Surface Coating of Polytetrafluoroethylene with Extracellular Matrix and Anti-CD34 Antibodies Facilitates Endothelialization and Inhibits Platelet Adhesion Under Sheer Stress

Chen L, He H, Wang M, Li X, Yin H

Expanded polytetrafluoroethylene (ePTFE) polymers do not support endothelialization because of nonconductive characteristics towards cellular attachment. Inner surface modification of the grafts can improve endothelialization and increase the long-term patency rate...
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Development of a Novel Subunit Vaccine Targeting Fusobacterium nucleatum FomA Porin Based on In Silico Analysis

Jeong K, Sao P, Park MJ, Lee H, Kim SH, Rhee JH, Lee SE

Selecting an appropriate antigen with optimal immunogenicity and physicochemical properties is a pivotal factor to develop a protein based subunit vaccine. Despite rapid progress in modern molecular cloning and recombinant...
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Characteristics of contact and distance osteogenesis around modified implant surfaces in rabbit tibiae

Choi JY, Sim JH, Yeo IS

PURPOSE: Contact and distance osteogenesis occur around all endosseous dental implants. However, the mechanisms underlying these processes have not been fully elucidated. We hypothesized that these processes occur independently of...
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The Influence of Urinary Catheter Materials on Forming Biofilms of Microorganisms

Lee KH, Park SJ, Choi S, Uh Y, Park JY, Han KH

Biofilms are commonly associated with an increased risk of catheter-associated infection. To study the efficacy of materials designed to reduce biofilm formation, microbial biofilms on clinically used urinary catheter were...
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Database construction of small–molecule inhibitors as bovine viral diarrhea virus (BVDV) RNA-dependent RNA polymerase: a cheminformatics approach

Chai HH, Choi BH, Park JE, Kim UH, Cho YM, Lim D

Bovine viral diarrhea virus (BVDV) is a major pathogen that may be one of the main reasons for economic losses in the livestock industry. BVDV is a well-characterized member of...
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Effect of Sub-minimal Inhibitory Concentration of Chlorhexidine on Biofilm Formation and Coaggregation of Early Colonizers, Streptococci and Actinomycetes

Lee SY, Lee SY

Chlorhexidine has long been used in mouth washes for the control of dental caries, gingivitis and dental plaque. Minimal inhibitory concentration (MIC) is the lowest concentration of an antimicrobial substance...
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Biocompatibility study of lithium disilicate and zirconium oxide ceramics for esthetic dental abutments

Brunot-Gohin C, Duval JL, Verbeke S, Belanger K, Pezron I, Kugel G, Laurent-Maquin D, Gangloff S, Egles C

PURPOSE: The increasing demand for esthetically pleasing results has contributed to the use of ceramics for dental implant abutments. The aim of this study was to compare the biological response...
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Comparative Study of Poly(L-Lactic Acid) Scaffolds Coated with Chitosan Nanoparticles Prepared via Ultrasonication and Ionic Gelation Techniques

Salehi M, Naseri-Nosar M, Azami M, Nodooshan , Arish J

In this study, an attempt was made to develop bi-functional constructs serving both as scaffolds and potential delivery systems for application in neural tissue engineering. The constructs were prepared in...
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Prospective randomized clinical trial of hydrophilic tapered implant placement at maxillary posterior area: 6 weeks and 12 weeks loading

Kim SB, Yun PY, Kim SY, Yi YJ, Kim JY, Kim YK

PURPOSE: Early loading of implant can be determined by excellent primary stability and characteristic of implant surface. The implant system with recently improved surface can have load application 4-6 weeks...
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Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Toxoplasma gondii Apical Membrane Antigen 1 (AMA1)

Vetrivel U, Muralikumar S, Mahalakshmi B, Lily Therese K, Madhavan H, Alameen M, Thirumudi

Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. It causes encephalitis, uveitis, chorioretinitis, and congenital infection. T. gondii invades the host cell by...
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Effect of Sub-Minimal Inhibitory Concentrations of Antibiotics on Biofilm Formation and Coaggregation of Streptococci and Actinomycetes

Lee SY, Lee SY

Minimal inhibitory concentration (MIC) is the lowest antibiotic concentration that inhibits the visible growth of bacteria. Sub-minimal inhibitory concentration (Sub-MIC) is defined as the concentration of an antimicrobial agent that...
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