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Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp

Kang SG, Lee DY, Kang ML, Yoo HS

A normal prion protein (PrPc) is converted to a proteaseresistant isoform by an apparent self-propagating activity in transmissible spongiform encephalopathy, a neurodegenerative disease. The cDNA encoding open reading frame (ORF)...
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