- Heme Oxygenase-1: Its Therapeutic Roles in Inflammatory Diseases
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Pae HO, Chung HT
- KMID: 2167992
- Immune Netw.
- 2009 Feb;9(1):12-19.
- doi: 10.4110/in.2009.9.1.12
Heme oxygenase (HO)-1 is an inducible enzyme that catalyzes the first and rate-limiting step in the oxidative degradation of free heme into ferrous iron, carbon monoxide (CO), and biliverdin (BV),... -
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- A case of erythropoietic protoporphyria
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Bong HW, Lee JH, Lee YS, Kim JH
- KMID: 1693796
- Korean J Dermatol.
- 1993 Oct;31(5):817-822.
Erythropoietic protoporphyria, sometimes also called erythrohepitic protoporphyria or simple protoporphyria, is a heritable detect of heme synthesis in which the last enzyme of the heme synthetic pathway, ferrochelatase(or heme synthetase),... -
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- Heme products post-radiofrequency ablation obscure tumor recurrence on MR but not on PET-CT
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Ehsan SR, Gooden CE, Schuster D
- KMID: 2052016
- Nucl Med Mol Imaging.
- 2012 Jun;46(2):152-154.
No abstract available. -
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- Effects of Oxidative Stress and Antioxidant on the Expression of Heme Oxygenase-1 in Human RPE
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Kim YJ, Chin HS
- KMID: 2212543
- J Korean Ophthalmol Soc.
- 2009 Aug;50(8):1247-1253.
- doi: 10.3341/jkos.2009.50.8.1247
PURPOSE: To evaluate the effects of oxidative stress and antioxidantson heme oxygenase-1 (HO-1) in cultured human retinal pigment epithelial (RPE) cells. METHODS: Cultured RPE cells were challenged with different concentrations... -
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- Effect of heme oxygenase induction by NO donor on the aortic contractility
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Kim CK, Sohn UD, Lee SY
- KMID: 1606843
- Korean J Physiol Pharmacol.
- 2001 Feb;5(1):87-92.
Carbon monoxide (CO) binds to soluble guanylate cyclase to lead its activation and elicits smooth muscle relaxation. The vascular tissues have a high capacity to produce CO, since heme oxygenase-2 (HO-2) is constitutively... -
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- Effect of the Heme Oxygenase Inhibitor on the Hypoxic Ischemic Brain Injury in the Neonatal Rat
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Bang JY, Park PH
- KMID: 1862249
- Korean J Anesthesiol.
- 2006 Jun;50(6):706-713.
- doi: 10.4097/kjae.2006.50.6.706
BACKGROUND: The heme oxygenase system catalyzes the conversion of heme to free iron, carbon monoxide and bilirubin. This study was purposed to evaluate the effect of the heme oxygenase inhibitor,... -
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- Low Dose Carbon Monoxide Inhalation Prevents Chronic Allograft Nephropathy following Kidney Transplantation in Rats. Heme Oxygenase-1 Derivatives Study I
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Yoon M
- KMID: 2211161
- J Korean Surg Soc.
- 2008 May;74(5):323-329.
PURPOSE: Carbon monoxide (CO), a product of heme catalysis by heme oxygenase (HO-1, HO-2, HO-3), induces cytoprotection against ischemia/reperfusion (I/R) injury in a variety of organs such as the heart,... -
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- The Effect of ABO Blood Groups, Hemoglobinopathy, and Heme Oxygenase-1 Polymorphisms on Malaria Susceptibility and Severity
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Kuesap J, Na-Bangchang K
- KMID: 2412735
- Korean J Parasitol.
- 2018 Apr;56(2):167-173.
- doi: 10.3347/kjp.2018.56.2.167
Malaria is one of the most important public health problems in tropical areas on the globe. Several factors are associated with susceptibility to malaria and disease severity, including innate immunity... -
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- Role of Carbon Monoxide in Neurovascular Repair Processing
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Choi YK
- KMID: 2429047
- Biomol Ther.
- 2018 Mar;26(2):93-100.
- doi: 10.4062/biomolther.2017.144
Carbon monoxide (CO) is a gaseous molecule produced from heme by heme oxygenase (HO). Endogenous CO production occurring at low concentrations is thought to have several useful biological roles. In... -
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- Immunohistochemical localization of heme oxygenase isozymes in the aged rat retina
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Lee HY
- KMID: 1558433
- Korean J Anat.
- 2001 Apr;34(2):169-179.
Heme oxygenase (HO)-1 and -2 isozymes are important markers for the oxidative stress. We localized HO-1 and HO-2 immunoreactivities and assessed the effect of aging on distribution of HO in... -
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- Ischemia/reperfusion Lung Injury Increases Serum Ferritin and Heme Oxygenase-1 in Rats
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Park YY
- KMID: 2071669
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):181-187.
- doi: 10.4196/kjpp.2009.13.3.181
Intestinal ischemia/reperfusion (I/R) is one of common causes of acute lung injury (ALI). Early and accurate diagnosis of patients who are like to develop serious acute respiratory distress syndrome (ARDS)... -
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- Heme Oxygenase-1 Induced by Aprotinin Inhibits Vascular Smooth Muscle Cell Proliferation Through Cell Cycle Arrest in Hypertensive Rats
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Choi HC, Lee KY, Lee DH, Kang YJ
- KMID: 2071686
- Korean J Physiol Pharmacol.
- 2009 Aug;13(4):309-313.
- doi: 10.4196/kjpp.2009.13.4.309
Spontaneous hypertensive rats (SHR) are an established model of genetic hypertension. Vascular smooth muscle cells (VSMC) from SHR proliferate faster than those of control rats (Wistar-Kyoto rats; WKY). We tested... -
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- A Case of Porphyria with reversible MRI findings
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Kang SY, Ma HI, Kwak KH, Lee SA
- KMID: 2342655
- J Korean Neurol Assoc.
- 1998 Apr;16(2):241-244.
The porphyrias are inherited or acquired disorders of specific enzymes in the heme biosynthetic pathway. Porphyrias have diverse neurologic manifestations with unknown mechanism. Some authors have proposed ischemic vasculopathy... -
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- Possible Role of Heme Oxygenase-1 and Prostaglandins in the Pathogenesis of Cerebral Malaria: Heme Oxygenase-1 Induction by Prostaglandin D2 and Metabolite by a Human Astrocyte Cell Line
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Kuesap J, Na-Bangchang K
- KMID: 1102782
- Korean J Parasitol.
- 2010 Mar;48(1):15-21.
- doi: 10.3347/kjp.2010.48.1.15
Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium... -
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- Acute Intermittent Porphyria and Pregnancy
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Ryu JH, Choi EA, Choi HM, Kim TY, Cho JS, Park YW, Kim JW
- KMID: 1924482
- Korean J Obstet Gynecol.
- 1997 Feb;40(2):414-418.
The Porphyria are a group of inherited and acquired disorders characterized by partial defects in the heme biosynthetic pathway. Among the hepatic forms, acute intermittent porphyria(AIP) is the most severe... -
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- Iron Contents in Rice Food Derived from the Iron Pot, and In Vitro Study Regarding Heme Oxygenase-1 Activity
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Kim KY, An YM, Kim TW, Jun YH, Lee JE, Jang JH, Kim SK
- KMID: 2358362
- Clin Pediatr Hematol Oncol.
- 2016 Oct;23(2):77-82.
- doi: 10.15264/cpho.2016.23.2.77
BACKGROUND: Iron pots have long been used for cooking in several countries. Early studies have shown that the use of such iron pots can increase the iron content of food... -
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- Modulation of Melanogenesis by Heme Oxygenase-1 via p53 in Normal Human Melanocytes
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Lim HS, Jin S, Yun SJ
- KMID: 2152655
- Chonnam Med J.
- 2016 Jan;52(1):45-52.
- doi: 10.4068/cmj.2016.52.1.45
As a key regulator of melanogenesis, p53 controls microphthalmia-associated transcription factor (MITF) and tyrosinase expression. The anti-oxidant enzyme heme oxygenase-1 (HO-1) is induced by various forms of cellular stress and... -
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- Effects of Heme Oxygenase-1 Expression in Mycophenolic Acid Induced Apoptosis of Jurkat Cell Lines
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Lee HK, Choi SJ
- KMID: 2211964
- J Korean Surg Soc.
- 2010 Jun;78(6):343-349.
- doi: 10.4174/jkss.2010.78.6.343
PURPOSE: This study demonstrates that pharmacologic induction of heme oygenase-1 (HO-1) along with catalytic activation significantly modulated apoptosis of Jurkat cells induced by mycophenolic acid (MPA). METHODS: Cells were cultured with... -
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- Change of Expression and Activity of Heme Oxygenase-1 in Rat Corpus Cavernosum during Low-flow Priapism
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Kim WJ, Jung HK, Jung JH, Kam SC, Hwa JS, Hyun JS
- KMID: 2298704
- Korean J Androl.
- 2004 Aug;22(2):81-86.
PURPOSE: The inducible isoform of heme oxygenase(HO), HO-1, responds to hypoxia. HO-1 regulates vascular smooth muscle tone through carbon monoxide production. To investigate the possible role of HO-1 in low-flow... -
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- Neuroprotective Effects of Betaxolol Mediated by Heme Oxygenase-1 Induction in RGC-5
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Cha JB, Kwon MY, Chung SW, Woo JM
- KMID: 2213854
- J Korean Ophthalmol Soc.
- 2016 Jan;57(1):113-119.
- doi: 10.3341/jkos.2016.57.1.113
PURPOSE: To evaluate the neuroprotective effects of betaxolol (betaxolol hydrochloride) under hypoxic conditions using retinal ganglion cells (RGC-5) and determine whether heme oxygenase-1 (HO-1) expression exerts cytoprotective effects. METHODS: In this... -
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