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The Expression of Fas antigen and Bax and Apoptosis in Ex Vivo Expanded Hematopoietic Progenitor Cells

Kim CK, Lee NS, Bae SB, Lee KT, Park SK, Jang KH, Cheong HJ, Kim SJ, Won JH, Park HS, Hong DS

  • KMID: 2252536
  • Korean J Hematol.
  • 2004 Jun;39(2):95-102.
BACKGROUND: During ex vivo expansion of cord blood (CB) CD34+ cells, differentiation of the expanded cells happened and hematopoietic potential of the progenitor cells decreased. In this study, we evaluate...
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Ex Vivo Expansion of Cryopreserved Cord Blood Cells

Kim S, Kim CH, Bae GB, Kim HS, Park SJ, Kim JS, Yun HJ, Jo DY

  • KMID: 2038489
  • Korean J Hematol.
  • 1997 Nov;32(3):347-359.
BACKGROUND: Cord blood (CB), which has no HLA restriction, is an alternative to bone marrow for hematopoietic stem cell transplantation. The use of cord blood, however, is limited by the...
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Serum Level of G-CSF and GM-CSF and CFU-GM Response to Hematopoietic Growth Factors in a Patient with Cyclic Neutropenia

Lee YK, Kim SH, Kim KW, Lee S, Kim HS, Chun DS, Lee KS

  • KMID: 2207356
  • J Korean Pediatr Soc.
  • 2001 Oct;44(10):1168-1175.
PURPOSE: Serum levels of G-CSF and GM-CSF were measured and CFU-GM assay using G- CSF, GM-CSF and SCF was conducted to evaluate the influence of hematopoietic growth factor on the...
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Characterization of CD34 Positive Cord Blood Cells and Ex-vivo Effects of Thrombopoietin on the Expansion of Human Umbilical Cord Blood

Lee WI, Choi YM, Suh JT, Lee HJ

  • KMID: 2300517
  • Korean J Clin Pathol.
  • 1999 Feb;19(1):118-124.
BACKGROUND: Umbilical cord blood (UCB) cells are an alternative source of hemopoietic stem cells for transplantation. However, the use of UCB is limited by the lack of number of hemopoietic...
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Influences of Hematopoietic Growth Factors on CFU-GM and CD34 Positive Cells of Mobilized Peripheral Blood Progenitors

Kwon KY

  • KMID: 2038488
  • Korean J Hematol.
  • 1997 Nov;32(3):333-346.
BACKGROUND: Peripheral blood progenitor cells (PBPC) mobilized by hematopoietic growth factors such as G-CSF or GM-CSF are increasingly being used instead of bone marrow to allow hematopoietic reconstitution after myeloablative...
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Megakaryocyte Colony Formation According to the Origin of Hematopoietic Stem Cell

Cho SB, Kim HS, Kang CM

  • KMID: 2278137
  • Korean J Pediatr Hematol Oncol.
  • 1998 Apr;5(1):138-147.
BACKGROUND: Development of hematopoietic growth factor made it possible to treat anemia and granulocytopenia following intensive chemotherapy and for thrombocytopenia, recently found thrombopoietin(TPO) is being applied experimentally in several countries....
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Comparison of Hematopoietic Stem Cell Activity in Normal Bone Marrow, in vivo G-CSF Stimulated Bone Marrow, and G-CSF-Mobilized Peripheral Blood

Rhim HS, Lee JW, Min CG, Hong HS, Min WS, Kim CC

  • KMID: 2300130
  • Korean J Blood Transfus.
  • 2000 Dec;11(2):157-167.
BACKGROUND: Classically, bone marrow (BM) has been the sole source of hematopoietic stem cell transplantation, but limitations of conventional bone marrow transplantation have stimulated a search for alternative sources of...
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Effect of Propofol Exposure on Hematopoiesis in Mouse Bone Marrow

Song HK, Jeong DC, Min TK

BACKGROUND: It is evident that inhalational anesthetics, such as nitrous oxide, possess a certain degree of myelodepressive effect in humans. However, unlike nitrous oxide, propofol is frequently recommended for the...
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The Effect of Uremic Plasma on the Proliferative Activity of CFU-GM in in-vitro Culture of Mouse Bone Marrow

Park CS, Yoo JY

  • KMID: 2274837
  • Korean J Pathol.
  • 1987 Dec;21(4):215-226.
The increased susceptibility in patients of chronic renal failure to infection has been reported to be attributed to defects in granulocyte and lymphocyte function and proliferative activity of hematopoietic cells....
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Characterization of Peripheral Blood CD34+ Cells Mobilized by Recombinant Human Granulocyte-Colony Stimulating Factor in Healthy Adult Donors

Byun JR, Chung IJ, Kwon SY, Seo JS, Choi KS, Park MR, Lee JJ, Kim HJ

  • KMID: 1849145
  • Korean J Hematol.
  • 1998 Oct;33(3):411-420.
BACKGROUND: CD34+ cells are capable of engraftment and hematopoietic reconstitution. However, expression patterns of other surface antigens such as CD13, CD33, CD38 and HLA-DR on CD34+ cells in mobilized peripheral...
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Correlation between Progenitor Cell Dose and the Rate of Engraftment in Autologous Peripheral Blood Stem Cell Transplantation and Allogeneic Bone Marrow Transplantation

Woo HY, Kim HR, Seong KW, Lee HK, Oh WI, Kim DW

  • KMID: 2253974
  • Korean J Blood Transfus.
  • 2000 Jun;11(1):35-47.
BACKGROUND: Bone marrow transplantation (BMT) or peripheral blood stem cell transplantation (PBSCT) following high dose chemotherapy has been an important therapeutic option for patients with hematologic malignancies or some solid...
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The Effect of Cord Blood Plasma on Hematopoietic Colony Formation

Min HG, Jeong DC, Han H, Kim HK, Oh CK

  • KMID: 2278190
  • Korean J Pediatr Hematol Oncol.
  • 1999 Oct;6(2):339-346.
PURPOSE: Umbilical cord blood transplantation is a alternative method as new hematopoietic stem cell transplantation and has been performed clinically in indicated disease. However, it have the problems for...
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Effects of Hematopoietic Growth Factors on the Bone Marrow and Mobilized Peripheral Progenitors from the Same Person

Kwon KY

  • KMID: 2143380
  • Korean J Hematol.
  • 1997 Aug;32(2):221-233.
BACKGROUND: Peripheral blood progenitor cell (PBPC) is now widely used as alternate source to bone marrow for transplantation. The objectives of this study are to compare the clonogenic potential of...
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Evaluation of Hematopoietic Abnormalities and Apoptosis in Myelodysplastic Syndromes Using Long Term Bone Marrow Culture System and In Situ Nick End Labeling Method

Won JH, Hong DS, Park HS, Lee JS

  • KMID: 2251588
  • Korean J Med.
  • 1997 Oct;53(4):469-481.
OBJECTIVES: The myelodysplastic syndromes (MDS) are a group of acquired clonal hematopoietic disorders characterized by peripheral cytopenias and a hypercellular or normocellular dysplastic bone marrow. The mechanisms responsible for development...
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Distribution and Characteristics of CD133+, CD34+ Cells in Counterflow Centrifugal Elutriation Fraction of Cord Blood and Bone Marrow

Park HJ, Chung NG, Kim SY, Jeong DC, Jang PS, Cho B, Kim HK

  • KMID: 2037384
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):17-25.
PURPOSE: Many studies for hematopoietic stem cell have investigated CD133, instead of CD34, as a new surrogate stem cell marker. Counterflow centrifugal elutriation (CCE) is a physical separation of a...
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Comparison of Amicus and CS-3000 Plus for the Collection of Peripheral Blood Stem Cells

Lee JS, Cho D, Shin MG, Ryang DW, Lee JJ, Kim HJ, Chae HJ, Shin JH, Suh SP

  • KMID: 2300076
  • Korean J Blood Transfus.
  • 2006 Jun;17(1):39-47.
BACKGROUND: The efficient collection of peripheral blood stem cells (PBSC) from donors who donate for allogeneic transplants as well as from patients undergoing autologous transplants is essential for a successful...
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Short & Long-term Repopulating Capacity of Cord Blood Cells That Are Stored Overnight before Cryopreservation

Jung YS, Kim SJ, Kim KH, Kim HJ, Kim SH, Kim HJ, Lee SC, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Hong DS, Park HS, Won JH

  • KMID: 1466814
  • Korean J Blood Transfus.
  • 2009 Apr;20(1):14-22.
BACKGROUND: Umbilical cord blood (UCB) is generally stored overnight and it undergoes a CD34 positive selection process the next day for reducing the cost and due to the convenience. We...
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Comparison of Hematopoietic Stem Cell Containing Fractions between Cryopreserved-thawed Cord Blood and Mobilized Peripheral Blood

Koh SH, Choi HS, Park ES, Kang HJ, Ahn HS, Shin HY

  • KMID: 2072544
  • Korean J Pediatr Hematol Oncol.
  • 2005 Oct;12(2):310-316.
PURPOSE: Discordance with expectation there are a few differences in hematopoietic stem cells according to their source. The purpose of this study is to compare the cryopreservative potential of hematopoiectic...
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Direct Comparsion of Long-Term Culture-Initiating Cells in Bone Marrow, Umbilical Cord Blood and Peripheral Blood Stem Cells

Kim JA, Hong DS, Kim SJ, Kim DW, Lee JW, Han CW, Min WS, Park HS, Kim CC, Kim DJ

  • KMID: 1534092
  • Korean J Hematol.
  • 1999 Feb;34(1):71-79.
BACKGROUND: Classically bone marrow (BM) is the major source of hematopoietic stem cells for the transplantation. Recently, hematopoietic stem cells circulating in peripheral nlood and umbilical cord stem cells have...
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Hematopoietic Recovery of Peripheral Blood Stem Cells Stored at 4degrees C

Cho SG, Oh EJ, Lee JM, Kim HK, Lee KS, Kim CC

  • KMID: 2175031
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):647-654.
PURPOSE: Cryopreservation has been the standard method of storing hematopoietic cells for the past 20 years, but this prdegrees Cedure is laborious and expensive. So, we evaluated the hematopoietic recovery of stored...
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